Production of Nonverbal Acoustic Signals and Resulting Physiological Responses

NCT05238285 | Recruiting

• 2 other identifiers: 20CH2592020-A03457-32:
• Study Type: observational
• Target: 2,000
• Locations: 1 country
• Sites: 1

Brief Summary

Like many other animals, humans produce nonverbal vocal signals including screams, grunts, roars, cries and laughter across a variety of contexts. However, despite their importance in the human vocal repertoire, the mechanisms and functions of non-verbal signals remain little studied and poorly understood in humans.Our studies aim to improve our understanding of the nature and function of non-verbal signals.

Conditions

Self-Perception

Keywords

acoustic analysis; physiological responses; psycho-acoustic tests

Outcome Measures

Primary Outcomes (1)

• Vocal analysis

  Participants will receive instructions on what to say or what type of non-verbal vocalisation to produce during the manipulation. The vocalisations thus produced by the participants will be systematically recorded and analysed using software adapted to acoustic analysis Measurement of acoustic variables such as fundamental frequency (pitch), vocal tract resonances (formants) and vocal disturbances (jitter, shimmer), the nonlinearities and chaotic/noise properties of vocalisations

  During the vocal production

Secondary Outcomes (5)

• Heart rate (bpm)

  During the vocal production

• Skin conductance (Siemens)

  During the vocal production

• Skin temperature (°C)

  During the vocal production

• Nociception Level Index (NOL)

  During the vocal production

• Pupillary diameter (millimeter)

  During the vocal production

Study Arms (1)

Healthy adult population aged 18 to 80 years

Participants will be asked to produce vocal sounds of different nature according to the non-verbal parameters of interest for the given study.

Behavioral: Production of vocal sounds

Interventions

Production of vocal sounds BEHAVIORAL

Participants will be asked to produce vocal sounds of different nature according to the non-verbal parameters of interest for the given study. For example, they can read a script containing vowels ('a', 'e', 'i', 'o', 'u'), short sentences ('hello, how are you'), longer passages of standardised reading texts, and can also be asked to speak freely about any topic ('freedom of speech'). They can be asked to play a role or to imitate a particular emotional state. For example, "imagine that you have just been told that you have won a million euros in the lottery. Produce a vocalisation to express your excitement" or "talk to your dog your dog by imagining that he has done a negative action and then do the same thing by imagining that this time imagining that the action was positive".

Healthy adult population aged 18 to 80 years

Eligibility Criteria

• Age: 18 Years - 80 Years
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

Healthy adult population aged 18 to 80 years

You may qualify if:

• \- Participant should be affiliated or entitled to a social security scheme

You may not qualify if:

• Pregnant women
• Voice production disorders
• Hearing impairment, speech production disorders or major health problems.
• Chronic smoker (more than 10 cigarettes per day)

Sponsors & Collaborators

• University of Lyon: collaborator
• Centre Hospitalier Universitaire de Saint Etienne: lead

Study Sites (1)

Centre Hospitalier Universitaire de Saint-Etienne

Saint-Etienne, 42055, France

RECRUITING

Study Officials

• ROLAND PEYRON, MDPHD

  Centre Hospitalier Universitaire de Saint Etienne

  PRINCIPAL INVESTIGATOR

• Nicolas MATHEVON, PhD

  University of Saint-Etienne, France

  STUDY DIRECTOR

Central Study Contacts

ROLAND PEYRON, MDPhD

CONTACT

(0)477127805; roland.peyron@chu-st-etienne.fr

Nicolas MATHEVON, PhD

CONTACT

04 77 48 50 22; nicolas.mathevon@univ-st-etienne.fr

Study Design

• Study Type: observational
• Observational Model: OTHER
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: February 2, 2022
• First Posted: February 14, 2022
• Study Start: March 8, 2023
• Primary Completion (Estimated): April 1, 2027
• Study Completion (Estimated): April 1, 2027
• Last Updated: May 6, 2026

Record last verified: 2026-05

Data Sharing

• IPD Sharing: Will not share

Locations

FR (1)