SCD Fit Homebase Program

NCT05228756 | Withdrawn

• 1 other identifier: 300008284
• Study Type: interventional
• Target: N/A
• Locations: 0 countries
• Sites: N/A

Brief Summary

The purpose of this project is to develop novel approaches to promote health and longevity while enhancing quality of life among persons with Sickle cell disease (SCD). Therefore, investigators are aiming to adapt an evidence-based exercise intervention for adults with SCD informed by culturally- relevant and biologic factors.

Conditions

Cardiovascular Diseases; Sickle Cell Disease; Exercise

Outcome Measures

Primary Outcomes (1)

• Feasibility will be measured

  Outcome will be to collect preliminary data on feasibility of the exercise intervention using rates of recruitment and retention

  One year

Secondary Outcomes (1)

• Acceptability will be measured

  One year

Other Outcomes (1)

• Tolerability will be measured

  One year

Study Arms (1)

Resistance Band exercise for Sickle Cell Disease

OTHER

Participants will complete 16 exercise session at home wearing an accelerometer

Other: Accelerometer

Interventions

Accelerometer OTHER

Participants will complete 16 exercise sessions at home wearing an accelerometer

Resistance Band exercise for Sickle Cell Disease

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• Eligible participants will include ambulatory adult patients of all SCD genotypes who are in care at UAB's sickle cell center and provide consent to participate in the study.
• Eligible participants include adults with SCD of any genotype older than 18 yrs. of age followed by the UAB sickle cell center.
• Participants must be in steady-state disease defined as not having a vaso-occlusive crisis or SCD-related hospitalization within four weeks of enrollment.

You may not qualify if:

• Participants will be excluded if they have severe avascular necrosis of the hip, are pregnant, or have absolute contraindications to exercise according to the American Heart Association (AHA) and American College of Sports Medicine guidelines

Sponsors & Collaborators

• University of Alabama at Birmingham: lead

MeSH Terms

Conditions

Cardiovascular Diseases; Anemia, Sickle Cell; Motor Activity

Condition Hierarchy (Ancestors)

Anemia, Hemolytic, Congenital; Anemia, Hemolytic; Anemia; Hematologic Diseases; Hemic and Lymphatic Diseases; Hemoglobinopathies; Genetic Diseases, Inborn; Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Behavior

Study Officials

• Foluso Ogunsile, MD

  University of Alabama at Birmingham

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: NA
• Masking: NONE
• Purpose: OTHER
• Intervention Model: SINGLE GROUP
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Assistant Professor

Study Record Dates

• First Submitted: December 9, 2021
• First Posted: February 8, 2022
• Study Start: November 1, 2022
• Primary Completion: December 1, 2023
• Study Completion: December 1, 2023
• Last Updated: October 19, 2022

Record last verified: 2022-10