Sickle Cell Disease
795
131
185
397
Key Insights
Highlights
Success Rate
83% trial completion
Published Results
167 trials with published results (21%)
Research Maturity
397 completed trials (50% of total)
Clinical Risk Assessment
Based on trial outcomes
Moderate Risk
Score: 49/100
10.6%
84 terminated out of 795 trials
82.5%
-4.0% vs benchmark
11%
89 trials in Phase 3/4
42%
167 of 397 completed with results
Key Signals
Data Visualizations
Phase Distribution
Trial Status
Trial Success Rate
Benchmark: 86.5%
Based on 397 completed trials
Clinical Trials (795)
Transplantation of Clustered Regularly Interspaced Short Palindromic Repeats Modified Hematopoietic Progenitor Stem Cells (CRISPR_SCD001) in Patients With Severe Sickle Cell Disease
Dietary Intake and Dietary Behaviors in Adults With Sickle Cell Disease
A Study Evaluating the Efficacy, Safety, Pharmacokinetics, and Pharmacodynamics of Crovalimab as Adjunct Treatment in Prevention of Vaso-Occlusive Episodes (VOE) in Sickle Cell Disease (SCD)
Study of a Single Dose of a 21-valent Pneumococcal Conjugate Vaccine in Children and Adolescents With Sickle Cell Disease
Functional Ovarian Reserve in Sickle Cell Disease
Collection of Human Biospecimens for Basic and Clinical Research Into Globin Variants
Secondary Pulmonary Hypertension in Adults With Sickle Cell Anemia
Managed Access Programs for SEG101, Crizanlizumab
Open-Label Extension Study to Pioneer Study 6058-SCD-101
Intravenous L-Citrulline for Vaso-occlusive Pain Episode in Sickle Cell Disease
Sickle Cell Disease Obstetric Multi-Disciplinary Care Programme
The Efficacy and Safety of Rilzabrutinib in Participants Aged 10 to 65 Years With Sickle-cell Disease
Alendronate for Osteonecrosis in Adults With Sickle Cell Disease
Ultrasound Acute Chest Syndrome Sickle Cell Disease
Alternative Dosing And Prevention of Transfusions (ADAPT)
Biotin-Acridine Red Cell Exchange Kinetics
Living With Sickle Cell Disease in the COVID-19 Pandemic
A Study of Immune Suppression Treatment for People With Sickle Cell Disease or β-Thalassemia Who Are Going to Receive an Allogeneic Hematopoietic Cell Transplantation (HCT)
Blood Collection for Research Related to Certain Diseases Involving Blood Vessels
Study of the Effect of Etavopivat on Cerebral Hemodynamic Response in Children With Sickle Cell Disease