Fascia Iliaca Compartment Block Versus Quadratus Lumborum Block in Total Hip Arthroplasty

NCT05228028 | Completed

• 1 other identifier: 2112-062-1282
• Study Type: interventional
• Target: 80
• Locations: 1 country
• Sites: 1

Brief Summary

Patients undergoing total hip arthroplasty are randomly assigned to two groups (fascia iliaca compartement block \[FICB\] group or quadratus lumborum block \[QLB\] group). In the FICB group, ultrasound-guided suprainguinal FICB (30 ml of 0.375% ropivacaine with 75 µg of epinephrine) is performed on the ipsilateral surgical side at the end of surgery. In the QLB group, ultrasound-guided anterior QLB (30 ml of 0.375% ropivacaine with 75 µg of epinephrine) is done on the ipsilateral surgical side at the end of surgery. A standardized multimodal analgesic regimen is used for postoperative pain control. The total use of opioids including patient-controlled analgesia and rescue analgesics is compared in both groups for 24 hours after surgery. The amount of opioids used is compared by conversion to oral morphine equivalent dose. Pain score at rest and movement during postoperative 24 hours, time to first request for analgesics, the incidence of side effects, patient satisfaction for pain control at postoperative 24 hours, quality of recovery at postoperative 24 hours, time to discharge readiness, and hospital length of stay are compared.

Conditions

Nerve Block; Pain, Postoperative

Outcome Measures

Primary Outcomes (1)

• Total opioids use for 24 hours

  Total dose of opioids used upto 24 hours after surgery (morphine milligram equivalents)

  Over the first 24 hours after surgery

Secondary Outcomes (8)

• Postoperative pain at rest (Numeric rating scale)

  At postoperative 4, 8, 12, 16, 20, 24 hours

• Postoperative pain with movement (Numeric rating scale)

  At postoperative 4, 8, 12, 16, 20, 24 hours

• Time to first request for pain medication

  From the end of surgery to discharge, an average of 4 days

• Incidence of postoperative nausea and vomiting

  Over the first 24 hours after surgery

• Patient satisfaction score with pain control at 24 hours after surgery

  At 24 hours after surgery

Study Arms (2)

fascia iliaca compartement block [FICB] group

EXPERIMENTAL

Procedure: fascia iliaca compartement block

quadratus lumborum block [QLB] group

EXPERIMENTAL

Procedure: quadratus lumborum block

Interventions

fascia iliaca compartement block PROCEDURE

Ultrasound-guided suprainguinal FICB (30 ml of 0.375% ropivacaine with 75 µg of epinephrine) is done on the ipsilateral surgical side at the end of surgery.

Also known as: FICB

fascia iliaca compartement block [FICB] group

quadratus lumborum block PROCEDURE

Ultrasound-guided anterior QLB (30 ml of 0.375% ropivacaine with 75 µg of epinephrine) is done on the ipsilateral surgical side at the end of surgery.

Also known as: QLB

quadratus lumborum block [QLB] group

Eligibility Criteria

• Age: 19 Years - 70 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• Adult patients between the ages of 19 and 70 undergoing total hip arthroplasty under spinal anesthesia
• Be able to provide written consent to participate in clinical trials, understand the procedures of this clinical trial, and be able to properly fill out patient-reported questionnaires
• ASA physical status classification 1-2

You may not qualify if:

• ASA physical status classification 3-4
• Patients who are contraindicated to nerve blocks (hypersensitivity to local anesthetics, infection at the injection site, etc.)
• Patients with chronic pain and taking pain medications, antidepressants, and anticonvulsants
• Other major medical or psychiatric conditions that will affect response to treatment
• Refusal of intravenous patient-controlled analgesia
• Patients determined to be unsuitable for this clinical trial by the researchers

Sponsors & Collaborators

• Seoul National University Hospital: lead

Study Sites (1)

Seoul National University Hospital

Seoul, 03080, South Korea

Location

MeSH Terms

Conditions

Pain, Postoperative

Condition Hierarchy (Ancestors)

Postoperative Complications; Pathologic Processes; Pathological Conditions, Signs and Symptoms; Pain; Neurologic Manifestations; Signs and Symptoms

Study Officials

• Seokha Yoo, M.D.

  Seoul National University Hospital

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: DOUBLE
• Who Masked: INVESTIGATOR, OUTCOMES ASSESSOR
• Purpose: TREATMENT
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Clinical Assistant Professor

Study Record Dates

• First Submitted: January 18, 2022
• First Posted: February 8, 2022
• Study Start: March 22, 2022
• Primary Completion: October 21, 2022
• Study Completion: December 22, 2022
• Last Updated: December 28, 2022

Record last verified: 2022-12

Data Sharing

• IPD Sharing: Will not share

Locations

KR (1)