GOUTMETALSAIN: Comparison of the Perception of Metallic Taste According to Lingual Locations in Healthy Volunteers

NCT05227157 | Completed

• 1 other identifier: RIPH-CHV-10
• Study Type: observational
• Target: 60
• Locations: 1 country
• Sites: 1

Brief Summary

This is a mono center , observational study carried out within otorhinolaryngology department in CH Valence. This is a descriptive and exploratory study in healthy volunteers. Based on the hypothesis that Metallic taste is imperfectly assessed, this study will provide a better understanding of the Metallic Taste.

Conditions

Taste Disorders; Sensation Disorders; Taste, Metallic; Taste Disorder, Glossopharyngeal Nerve

Keywords

Taste, Metallic

Outcome Measures

Primary Outcomes (1)

• evaluation of the intensity of metallic taste

  visual analogue scale (0 to 5); A score of 5 means the highest intensity of metallic taste

  5 minutes

Study Arms (1)

1: intensity of perception of metallic taste

For this study, there is only one arm: swab with iron sulfate solution at a concentration of 10g/l. Each subject complete visual scale

Other: swab with iron sulfate solution

Interventions

swab with iron sulfate solution OTHER

measurement of the intensity of perception of metallic taste by affixing a swab iron sulfate solution 10g/l at 4 places on the tongue depending on the glossopharyngeal nerve: tip of the tongue (right and left); base of the tongue (right and left). Visual analogic Scale (0 to 5)

1: intensity of perception of metallic taste

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

healthy volonteers without olfactory and gustatory disorder

You may qualify if:

• Age ≥ 18 years old
• Healthy volunteers
• Read, write and understand the French language
• Patient affiliated to a social security system
• Written and signed informed consent

You may not qualify if:

• head and Neck cancer history
• olfactory and gustatory disorder
• Refusal to participate in research
• Patient under guardianship, deprived of liberty, safeguard of justice

Sponsors & Collaborators

• Centre Hospitalier de Valence: lead

Study Sites (1)

Ch Valence

Valence, Drome, 26953, France

Location

MeSH Terms

Conditions

Taste Disorders; Sensation Disorders; Glossopharyngeal Nerve Diseases

Condition Hierarchy (Ancestors)

Neurologic Manifestations; Nervous System Diseases; Signs and Symptoms; Pathological Conditions, Signs and Symptoms; Cranial Nerve Diseases

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: January 26, 2022
• First Posted: February 7, 2022
• Study Start: December 15, 2021
• Primary Completion: April 8, 2022
• Study Completion: May 1, 2022
• Last Updated: September 8, 2025

Record last verified: 2025-09

Locations

FR (1)