Whole Body Vibration and Tonic Vibration Reflex

NCT05209945 | Completed

• 1 other identifier: WBVTVR
• Study Type: interventional
• Target: 7
• Locations: 1 country
• Sites: 1

Brief Summary

Whole-body vibration (WBV) has beneficial neuromuscular effects on muscle strength increase. Supraspinal, spinal, and peripheral mechanisms have been proposed to explain these beneficial effects. The most commonly proposed explanatory mechanism is spinal segmental reflexes. However, the neuronal circuit and receptors of the reflex response have not been defined precisely. A group of researchers found that the reflex system is the Tonic vibration reflex (TVR) under the neuromuscular effects of WBV; Other researchers claim that WBV activates a different spinal reflex than TVR. Tonic vibration reflex is a polysynaptic reflex that occurs as a result of muscle spindle activation, in which more than 100 Hz vibrations are applied to the belly or tendon of the muscle. A group of researchers argues that WBV activates the spinal reflex response, but this reflex response is different from TVR. According to them, WBV-induced reflex (WBV-IR) response latency is longer than TVR latency. WBV activates TVR at very attenuated amplitude; WBV activates a different spinal reflex with longer latency at medium and high amplitude vibration. They reported that although the H-reflex, T-reflex, and TVR latency was longer in the spastic soleus muscle than normotonic soleus muscle, where the muscle spindle and Ia afferent pathway were hyperactive. However, the WBV-IR latency was similar in both spastic and normotonic soleus muscle. According to our hypothesis, the reflex system activated by WBV changes depending on vibration frequency: if the high-frequency (100-150 Hz) WBV is applied, the tonic vibration reflex is activated; if the low-frequency (30-40 Hz) WBV is applied, the bone myoregulation reflex is activated. The purpose of this research is to test this hypothesis.

Conditions

Vibration; Exposure; Muscle Physiology

Keywords

muscle strength; vibration; tonic vibration reflex

Outcome Measures

Primary Outcomes (4)

• WBV-IR latency

  Whole-body vibration induced reflex latency

  during intervention, an average of 1 minute

• TVR latency

  Tonic vibration reflex latency

  during intervention, an average of 1 minute

• Heel vibration induced reflex latency

  Vibration was applied to the right heel. The reflex latency induced by the heel vibration was measured.

  during intervention, an average of 1 minute

• T-reflex latency

  Latency of the Achilles tendon reflex

  during intervention, an average of 1 minute

Study Arms (1)

Vibration

EXPERIMENTAL

Vibration (WBV, heel, and tendon vibration) was applied to participants

Procedure: vibration

Interventions

vibration PROCEDURE

whole-body vibration, heel and soleus tendon vibrations were applied to the human body

Vibration

Eligibility Criteria

• Age: 20 Years - 45 Years
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64)

You may qualify if:

• Being healthy
• Being a young adult (20-45 years old)
• Volunteer

You may not qualify if:

• Scar, dermatitis, etc. in the skin tissue
• Kidney stone history
• Fracture in the lower extremity, history of orthopedic surgery
• Heart disease, Hypertension
• Dizziness
• Metabolic bone diseases, including osteoporosis
• History of bone occupying lesion, neoplasia, osteomyelitis
• Degenerative, inflammatory diseases of the joints of the lower extremities
• Lower extremity thrombophlebitis
• Lower extremity motor loss, sensory loss, muscle atrophy
• Subjects who cannot tolerate whole-body vibration

Sponsors & Collaborators

• Istanbul Physical Medicine Rehabilitation Training and Research Hospital: lead

Study Sites (1)

Istanbul Physical Medicine Rehabilitation Training & Research Hospital

Istanbul, 34173, Turkey (Türkiye)

Location

MeSH Terms

Interventions

Vibration

Intervention Hierarchy (Ancestors)

Mechanical Phenomena; Physical Phenomena

Study Officials

• İLHAN KARACAN

  Istanbul Physical Medicine Rehabilitation Training & Research Hospital

  STUDY CHAIR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: NA
• Masking: NONE
• Purpose: BASIC SCIENCE
• Intervention Model: SINGLE GROUP
• Sponsor Type: OTHER GOV
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Principal Investigator

Model Details: Single Group Assignment

Study Record Dates

• First Submitted: January 3, 2022
• First Posted: January 27, 2022
• Study Start: November 27, 2021
• Primary Completion: December 30, 2021
• Study Completion: December 31, 2021
• Last Updated: January 27, 2022

Record last verified: 2022-01

Locations

TU (1)