NCT03016286

Brief Summary

Hypotheses of this study are

  1. 1.Bone myoregulation reflex (BMR) inhibits presynaptically H-reflex during whole-body vibration (WBV)
  2. 2.Cooling of ankle abolishes the inhibitor effect of BMR on soleus H-reflex Aim of this study is to test these hypotheses.

Trial Health

35
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
10

participants targeted

Target at below P25 for not_applicable

Timeline
Completed

Started Nov 2017

Shorter than P25 for not_applicable

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

January 8, 2017

Completed
2 days until next milestone

First Posted

Study publicly available on registry

January 10, 2017

Completed
10 months until next milestone

Study Start

First participant enrolled

November 1, 2017

Completed
6 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

April 17, 2018

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

April 17, 2018

Completed
Last Updated

July 13, 2017

Status Verified

July 1, 2017

Enrollment Period

6 months

First QC Date

January 8, 2017

Last Update Submit

July 11, 2017

Conditions

Effects of Vibration

Keywords

Whole body vibrationBone myoregulation reflexH-reflex

Outcome Measures

Primary Outcomes (1)

  • Presynaptic Ia inhibition level

    1 month

Study Arms (1)

WBV group

EXPERIMENTAL

whole-body vibration (WBV) group

Other: vibration

Interventions

vibrationOTHER

Whole body vibration at 25Hz frequency

Also known as: Whole body vibration
WBV group

Eligibility Criteria

Age20 Years - 45 Years
Sexmale
Healthy VolunteersYes
Age GroupsAdult (18-64)

You may qualify if:

  • Healthy male
  • Right-handed men

You may not qualify if:

  • Bone, muscle/tendon, joint, vascular, dermatologic diseases in lower extremities and spine
  • Medication that could affect the musculoskeletal system
  • Postural abnormalities (scoliosis, kyphosis, etc)
  • Systemic diseases

Contact the study team to confirm eligibility.

Sponsors & Collaborators

MeSH Terms

Interventions

Vibration

Intervention Hierarchy (Ancestors)

Mechanical PhenomenaPhysical Phenomena

Study Design

Study Type
interventional
Phase
not applicable
Allocation
NA
Masking
NONE
Purpose
BASIC SCIENCE
Intervention Model
SINGLE GROUP
Sponsor Type
OTHER GOV
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Head of PMR clinic

Study Record Dates

First Submitted

January 8, 2017

First Posted

January 10, 2017

Study Start

November 1, 2017

Primary Completion

April 17, 2018

Study Completion

April 17, 2018

Last Updated

July 13, 2017

Record last verified: 2017-07

Data Sharing

IPD Sharing
Will not share