NCT04516798

Brief Summary

This study was conducted to determine whether the spinal reflex mechanism underlying the neuromuscular effects of whole body vibration (WBV) is tonic vibration reflex. Local and whole body vibration reflex latencies were measured in young adult healthy volunteers.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
8

participants targeted

Target at below P25 for not_applicable

Timeline
Completed

Started Oct 2020

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

August 14, 2020

Completed
4 days until next milestone

First Posted

Study publicly available on registry

August 18, 2020

Completed
2 months until next milestone

Study Start

First participant enrolled

October 5, 2020

Completed
2 days until next milestone

Primary Completion

Last participant's last visit for primary outcome

October 7, 2020

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

October 7, 2020

Completed
Last Updated

October 27, 2020

Status Verified

October 1, 2020

Enrollment Period

2 days

First QC Date

August 14, 2020

Last Update Submit

October 23, 2020

Conditions

Reflex, Ankle, Decreased

Keywords

whole body vibrationtonic vibration reflexmuscle spindle

Outcome Measures

Primary Outcomes (1)

  • reflex latency

    The time between the vibration stimulus and the reflex muscle response triggered by it was defined as the latency.

    during intervention, an average of 8 minutes

Study Arms (1)

Experiment

EXPERIMENTAL

Local and whole body vibration were applied

Other: vibration

Interventions

vibrationOTHER

local and whole-body vibration were applied

Experiment

Eligibility Criteria

Age20 Years - 40 Years
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64)

You may qualify if:

  • Healthy
  • Young adult (20-40 years old)
  • Both gender
  • Volunteer

You may not qualify if:

  • Cardiac disorder (Rhythm / conduction disorder, Cardiac pacemaker, Ischemic heart disease)
  • Finding or suspected active deep vein thrombosis,
  • History of deep vein thrombosis and pulmonary embolism,
  • Orthostatic hypotension
  • Hypertension
  • Presence of fracture in the lower limb
  • Achilles Contractures
  • Active inflammatory, rheumatological or infectious disease in the lower limb
  • Peripheral nerve lesions such as polyneuropathy, radiculopathy in the lower limb
  • Those with a history of Achilles tendinopathy / bursitis
  • Those with a history of kidney stones
  • Patients with dizziness and balance problems,
  • Cases with lesions on the skin surface where electrodes were attached
  • Those with communication-cooperation problems
  • Having a history of panic attacks

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Istanbul Physical Medicine Rehabilitation Training & Research Hospital

Istanbul, 34173, Turkey (Türkiye)

Location

Related Publications (3)

  • Yildirim MA, Topkara B, Aydin T, Paker N, Soy D, Coskun E, Ones K, Bardak A, Kesiktas N, Ozyurt MG, Celik B, Onder B, Kilic A, Kucuk HC, Karacan I, Turker KS. Exploring the receptor origin of vibration-induced reflexes. Spinal Cord. 2020 Jun;58(6):716-723. doi: 10.1038/s41393-020-0419-5. Epub 2020 Jan 15.

    PMID: 31942042RESULT

  • Aydin T, Kesiktas FN, Baskent A, Karan A, Karacan I, Turker KS. Cross-training effect of chronic whole-body vibration exercise: a randomized controlled study. Somatosens Mot Res. 2020 Jun;37(2):51-58. doi: 10.1080/08990220.2020.1720635. Epub 2020 Feb 5.

    PMID: 32024411RESULT

  • Karacan I, Cakar HI, Sebik O, Yilmaz G, Cidem M, Kara S, Turker KS. A new method to determine reflex latency induced by high rate stimulation of the nervous system. Front Hum Neurosci. 2014 Jul 18;8:536. doi: 10.3389/fnhum.2014.00536. eCollection 2014.

    PMID: 25100978RESULT

MeSH Terms

Conditions

Reflex, Abnormal

Interventions

Vibration

Condition Hierarchy (Ancestors)

Neurologic ManifestationsNervous System DiseasesSigns and SymptomsPathological Conditions, Signs and Symptoms

Intervention Hierarchy (Ancestors)

Mechanical PhenomenaPhysical Phenomena

Study Officials

  • Ilhan Karacan, Assoc Prof

    Istanbul Physical Medicine Rehabilitation Training & Research Hospital

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
NA
Masking
NONE
Purpose
BASIC SCIENCE
Intervention Model
SINGLE GROUP
Model Details: Self controlled experimental study
Sponsor Type
OTHER GOV
Responsible Party
SPONSOR

Study Record Dates

First Submitted

August 14, 2020

First Posted

August 18, 2020

Study Start

October 5, 2020

Primary Completion

October 7, 2020

Study Completion

October 7, 2020

Last Updated

October 27, 2020

Record last verified: 2020-10

Data Sharing

IPD Sharing
Will not share

Locations

TU(1)