NCT05198011

Brief Summary

Completely or partially edentulous patients suffer from resorption of the alveolar bone, they always seek rehabilitation which becomes challenging. Alveolar ridge augmentation is widely done now to offer these patients functional and esthetic restoration. Many techniques have been proposed to obtain good results of ridge augmentation. Titanium Mesh (TiMe) is widely used, also digital and computer-guided surgery now plays an important role to improve the techniques and results in ridge augmentation procedures.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
14

participants targeted

Target at below P25 for not_applicable

Timeline
Completed

Started Oct 2019

Shorter than P25 for not_applicable

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

Study Start

First participant enrolled

October 1, 2019

Completed
7 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

April 30, 2020

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

April 30, 2020

Completed
1.7 years until next milestone

First Submitted

Initial submission to the registry

January 4, 2022

Completed
16 days until next milestone

First Posted

Study publicly available on registry

January 20, 2022

Completed
Last Updated

January 20, 2022

Status Verified

January 1, 2022

Enrollment Period

7 months

First QC Date

January 4, 2022

Last Update Submit

January 14, 2022

Conditions

Outcome Measures

Primary Outcomes (2)

  • Change in bone volume

    Bone volume wa measured using CBCT

    at baseline and 6 months

  • Operation time

    Time of operation for each group will be calculated

    During the procedure

Study Arms (2)

3D mandibular ridge augmentation

EXPERIMENTAL
Procedure: 3D customized Titanium Mesh (Study)

Conventional mandibular ridge augmentation

ACTIVE COMPARATOR
Procedure: Conventional ridge augmentation (Control)

Interventions

approach for planning and augmenting atrophic posterior mandibular ridge using a pre-customized TiMe on a 3D model. The 3D surgical model will be virtually created from a cone-beam computed tomography (CBCT) and printed using Fused deposition modeling (FDM) machine. The 3D model will be then used to contour the TiMe in accordance with the needed amount of augmentation then will be used to help pack and contour the graft material.

3D mandibular ridge augmentation

the conventional technique of ridge augmentation using Titanium Mesh

Conventional mandibular ridge augmentation

Eligibility Criteria

Age40 Years - 60 Years
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64)

You may qualify if:

  • Patients will have a posterior mandibular atrophic ridge
  • Distance between the crest of the ridge and the superior border of the inferior alveolar canal will be from 5 mm to 7 m
  • Adequate inter-arch space

You may not qualify if:

  • Patients who have any uncontrolled systemic disease contraindicated to oral surgery ( Diabetes, hypertension, and patients under chemotherapy treatment )
  • Patients who have any relevant bone disease.
  • Patients who are smokers

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Alexandria Faculty of Dentistry

Alexandria, Egypt

Location

MeSH Terms

Conditions

Alveolar Bone Loss

Condition Hierarchy (Ancestors)

Bone ResorptionBone DiseasesMusculoskeletal DiseasesPeriodontal AtrophyPeriodontal DiseasesMouth DiseasesStomatognathic Diseases

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
NONE
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
SPONSOR INVESTIGATOR
PI Title
Assistant lecturer of DPH and Clinical statistician

Study Record Dates

First Submitted

January 4, 2022

First Posted

January 20, 2022

Study Start

October 1, 2019

Primary Completion

April 30, 2020

Study Completion

April 30, 2020

Last Updated

January 20, 2022

Record last verified: 2022-01

Locations