Comparing the Efficacy of WeChat-based Patient Education and Conventional Patient Education in the Management of Helicobacter Pylori Eradication
1 other identifier
observational
1,017
1 country
1
Brief Summary
we conducted a retrospective study to compare the efficacy of WeChat-based patient education and conventional patient education in the management of Helicobacter pylori eradication.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P75+ for all trials
Started Jul 2019
Typical duration for all trials
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
Study Start
First participant enrolled
July 1, 2019
CompletedPrimary Completion
Last participant's last visit for primary outcome
July 31, 2021
CompletedStudy Completion
Last participant's last visit for all outcomes
December 7, 2021
CompletedFirst Submitted
Initial submission to the registry
December 25, 2021
CompletedFirst Posted
Study publicly available on registry
January 11, 2022
CompletedMarch 23, 2022
March 1, 2022
2.1 years
December 25, 2021
March 8, 2022
Conditions
Keywords
Outcome Measures
Primary Outcomes (1)
eradication rate
Six weeks after completion of treatment，numbers of patients get H.pylori eradicated supported by negative 13C-UBT results will be investigated by an independent researcher.Then eradication rate in each group will be calculated by using intention-to-treat analysis and per-protocol analysis.
2 months
Secondary Outcomes (2)
compliance
14 days
prevalence of adverse events
14 days
Study Arms (2)
WeChat group
Control group
Interventions
patients in experimental group were asked to join a WeChat group, which was governed by experienced gastroenterologists. Relevant knowledge of H. pylori eradication was released in the group chat irregularly. Patients in WeChat group were allowed to ask questions at any time during the whole treatment process, soon afterwards, suggestions were given.
Eligibility Criteria
patients aged between 18-75 years old and had been prescribed a 14-day course of bismuth-contained quadruple therapy for H. pylori infection in our outpatient clinics between 1 July 2019 and 31 July 2021. H. pylori infection was confirmed by any two positive outcomes of rapid urease test,13C-urea breath test (UBT) and histopathology. Patients who had H. pylori therapy history, using other therapeutic regimens or unwilling to take prescribed medications were excluded.
You may qualify if:
- patients aged between 18 and 75 years old and have not been treated before.
You may not qualify if:
- Patients who had H. pylori therapy history, using other therapeutic regimens or unwilling to take prescribed medications were excluded. Demographic data, treatment regimens, outcomes of therapy, adherence to therapy and adverse event were retrieved.
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Study Sites (1)
Qilu hosipital
Jinan, Shandong, 250012, China
MeSH Terms
Interventions
Intervention Hierarchy (Ancestors)
Study Design
- Study Type
- observational
- Observational Model
- COHORT
- Time Perspective
- RETROSPECTIVE
- Sponsor Type
- OTHER
- Responsible Party
- PRINCIPAL INVESTIGATOR
- PI Title
- Professor, Director of gastroenterology department of Qilu hospital
Study Record Dates
First Submitted
December 25, 2021
First Posted
January 11, 2022
Study Start
July 1, 2019
Primary Completion
July 31, 2021
Study Completion
December 7, 2021
Last Updated
March 23, 2022
Record last verified: 2022-03