Feedback, Motor Sequence Learning, and Brain Connectivity

NCT04971486 | Completed

• 1 other identifier: Pro00097070
• Study Type: interventional
• Target: 33
• Locations: 1 country
• Sites: 1

Brief Summary

Feedback delivered during motor practice can help promote motor skill learning, enhance confidence, and alter brain connectivity. However, the optimal way to provide feedback to promote learning, confidence and brain connectivity is unknown. This project will study how the feedback that is provided during practice of a movement skill can help people learn and build confidence and whether these correspond to changes in brain function. The investigators will measure motor skill performance, confidence, and resting state brain connectivity before and after a session of motor practice.

Conditions

Adult

Keywords

Motor Learning; Feedback; Brain Function

Outcome Measures

Primary Outcomes (3)

• Response Time

  Time to complete one sequence

  Change from baseline to retention at 24 hours

• Task Confidence

  Self-reported confidence in ability to complete a sequence in a given time on a scale of 0 to 10 with a 10 equating to higher confidence

  Change from baseline to retention at 24 hours

• Brain Connectivity

  Resting state connectivity between pairs of brain regions

  Change from baseline to immediately after practice

Secondary Outcomes (15)

• Peak Velocity

  Change from baseline to retention at 24 hours

• Total Path Distance

  Change from baseline to retention at 24 hours

• Time to Peak Velocity

  Change from baseline to retention at 24 hours

• Perceived Competence

  Change from baseline to retention at 24 hours

• Perceived Interest/Enjoyment

  Change from baseline to retention at 24 hours

Study Arms (2)

Performance Feedback

EXPERIMENTAL

Practice of a joystick based motor sequence task. Participants receive feedback on their response time to complete the trials in the practice block.

Behavioral: Motor Sequence Task

Performance plus Positive Feedback

EXPERIMENTAL

Practice of a joystick based motor sequence task. Participants receive feedback on their response time to complete the trials in the practice block plus positive social comparative feedback.

Behavioral: Motor Sequence Task

Interventions

Motor Sequence Task BEHAVIORAL

Participants will be seated at a laptop with the right hand on a standard joystick. The movement of the joystick will move a cursor on the computer screen. Targets will appear on the laptop screen as a circle in one of twelve spatially distinct locations. The learner must move the joystick "cursor" to inside the target before the next target will appear.

Performance Feedback; Performance plus Positive Feedback

Eligibility Criteria

• Age: 18 Years - 40 Years
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64)

You may qualify if:

• Age 18 to 40 years
• Right-hand dominant

You may not qualify if:

• Medical diagnosis or medication that affects dopamine (e.g. dopamine reuptake inhibitors)
• Musculoskeletal issues that limit upper extremity movement
• Contraindications for magnetic resonance imaging (MRI)

Sponsors & Collaborators

• University of South Carolina: lead

Study Sites (1)

University of South Carolina

Columbia, South Carolina, 29208, United States

Location

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: SINGLE
• Who Masked: PARTICIPANT
• Purpose: BASIC SCIENCE
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Associate Professor

Study Record Dates

• First Submitted: July 20, 2021
• First Posted: July 21, 2021
• Study Start: April 1, 2021
• Primary Completion: January 10, 2022
• Study Completion: January 10, 2022
• Last Updated: January 13, 2022

Record last verified: 2022-01

Data Sharing

• IPD Sharing: Will share
• Shared Documents: STUDY PROTOCOL
• Time Frame: 1 year after study completion

Locations

US (1)