Gingival Recession Treatment Using Two Different Surgical Techniques

NCT04966208 | Completed

• 1 other identifier: FDBSUREC/08042021/FA
• Study Type: interventional
• Target: 24
• Locations: 1 country
• Sites: 1

Brief Summary

Coronally the advanced flap is considered a predictable treatment of gingival recession but in certain situations, it needs a filler like subperiosteal connective tissue graft (CTG) which is considered as the gold standard treatment approach. This randomized controlled trial compares the clinical benefits and effectiveness of a xenogenic collagen matrix (mucoderm, botiss, dental, Berlin, Germany) as a filler to the subperiosteal connective tissue graft (CTG).

Conditions

Gingival Recession; Root Planing

Keywords

root coverage; mucoderm; connective tissue; grafts

Outcome Measures

Primary Outcomes (1)

• The zone of keratinized gingiva

  The distance from the tip of the papilla to the mucogingival junction minus the probing depth measured in mm using graduated periodontal probe.

  6 months after the surgery

Secondary Outcomes (4)

• Periodontal probing depth

  6 months after the surgery

• Clinical attachment loss

  6 months after the surgery

• Gingival recession

  6 months after the surgery

• Patient satisfaction of the esthetics

  6 months

Study Arms (2)

root coverage surgeries using autologous connective tissue for treatment of gingival recession

ACTIVE COMPARATOR

root coverage surgeries using tunneling technique of autologous connective tissue as a treatment of Miller class two gingival recession

Procedure: xenogeneic collagen matrix

root coverage surgeries using xenogenic collagen matrix for treatment of gingival recession

EXPERIMENTAL

root coverage surgeries using tunneling technique of mucodrm membrane ; xenogeneic collagen matrix as a treatment of Miller class two gingival recession

Procedure: xenogeneic collagen matrix

Interventions

xenogeneic collagen matrix PROCEDURE

xenogeneic collagen matrix called mucoderm used for root coverage for treatment of gingival recession instead of harvesting from the patients connective tissue

root coverage surgeries using autologous connective tissue for treatment of gingival recession; root coverage surgeries using xenogenic collagen matrix for treatment of gingival recession

Eligibility Criteria

• Age: 18 Years - 60 Years
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64)

You may qualify if:

• The selected patients for this study are non-smokers, aged 18-60 years with multiple gingival recession (Miller class 1, or 2.) for more than two adjacent affected teeth with plaque score less than 25%

You may not qualify if:

• Patients with systemic complications, psychological problems, parafunctional habits, or patients presented with Mal-posed teeth, hypermobile teeth, teeth with Miller class 3 gingival recession were excluded from this study.

Sponsors & Collaborators

• Assiut University: lead

Study Sites (1)

Assiut University

Asyut, 71111111, Egypt

Location

MeSH Terms

Conditions

Gingival Recession

Condition Hierarchy (Ancestors)

Gingival Diseases; Periodontal Diseases; Mouth Diseases; Stomatognathic Diseases; Periodontal Atrophy

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: TRIPLE
• Who Masked: PARTICIPANT, CARE PROVIDER, INVESTIGATOR
• Purpose: TREATMENT
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Lecturer of Periodontology and Oral Implantology-Faculty of Dentistry, Assiut University, Egypt.

Study Record Dates

• First Submitted: June 21, 2021
• First Posted: July 19, 2021
• Study Start: September 1, 2020
• Primary Completion: March 1, 2021
• Study Completion: June 15, 2021
• Last Updated: July 19, 2021

Record last verified: 2021-07

Data Sharing

• IPD Sharing: Will not share

Locations

EG (1)