Text Message Quit Vaping Intervention for Adolescents

NCT04919590 | Completed Results DMC

• 1 other identifier: TruthInitiativeQVSTeen
• Study Type: interventional
• Target: 1,681
• Locations: 1 country
• Sites: 1

Brief Summary

This research study, conducted by Truth Initiative, will help us learn how text messaging can help adolescents between 13 and 17 years of age quit vaping.

Conditions

Vaping; Cessation, Tobacco

Keywords

Vaping cessation; Mobile intervention; Adolescents

Outcome Measures

Primary Outcomes (1)

• Self-reported 30-day Point Prevalence Abstinence

  In the past 30 days, did you vape at all, even a puff of someone else's?

  7 months post enrollment

Study Arms (3)

This is Quitting

EXPERIMENTAL

Participants will be enrolled to receive messages from This is Quitting. Users receive one age-appropriate message per day tailored to their enrollment date or quit date, which can be set and reset via text message. Those not ready to quit receive 4 weeks of messages focused on building skills and confidence. Users who set a quit date receive messages for a week preceding it and 8 weeks afterward that include encouragement and support, skill- and self-efficacy building exercises, coping strategies, and information about the risks of vaping, benefits of quitting, and cutting down to quit. Keywords COPE, STRESS, SLIP, and MORE provide on-demand support.

Behavioral: This is Quitting

Assessment only control

OTHER

After an initial enrollment message, participants will be contacted monthly to assess e-cigarette use. At the end of the study data collection period, they will receive information on how to sign up for This is Quitting if they are interested in the program.

Other: Assessment only control

Waitlist control

OTHER

After an initial enrollment message, participants will receive no contact from study staff except for 1-month and 7-month follow-up assessments. At the end of the study data collection period, they will receive information on how to sign up for This is Quitting if they are interested in the program.

Other: Waitlist control

Interventions

This is Quitting BEHAVIORAL

Text message-based intervention for quit vaping support.

This is Quitting

Assessment only control OTHER

Assessment only

Assessment only control

Waitlist control OTHER

No contact until follow-up survey, waitlisted to receive intervention post study

Waitlist control

Eligibility Criteria

• Age: 13 Years - 17 Years
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Child (0-17)

You may qualify if:

• Age 13-17
• Past 30-day use of e-cigarettes containing nicotine
• Interest in quitting e-cigarette use in the next 30 days
• US residence

You may not qualify if:

• Failure to confirm mobile number after initial sign-up

Sponsors & Collaborators

• Truth Initiative: lead

Study Sites (1)

Truth Initiative

Washington D.C., District of Columbia, 20001, United States

Location

Related Publications (2)

• Graham AL, Cha S, Jacobs MA, Amato MS, Funsten AL, Edwards G, Papandonatos GD. A Vaping Cessation Text Message Program for Adolescent E-Cigarette Users: A Randomized Clinical Trial. JAMA. 2024 Sep 3;332(9):713-721. doi: 10.1001/jama.2024.11057.

  PMID: 39110436 BACKGROUND

• Graham AL, Cha S, Do EK, Jacobs MA, Edwards G, Papandonatos GD. Dual abstinence from nicotine vaping and cannabis use among young people: secondary analyses from two U.S.-based randomized controlled trials of vaping cessation. Subst Abuse Treat Prev Policy. 2025 Nov 3;20(1):48. doi: 10.1186/s13011-025-00679-1.

  PMID: 41177894 DERIVED

MeSH Terms

Conditions

Vaping; Tobacco Use Cessation

Condition Hierarchy (Ancestors)

Smoking; Behavior; Health Behavior

Results Point of Contact

• Title: Dr. Amanda Graham
• Organization: Truth Initiative

vapestudy@truthinitiative.org

202-525-6473‬

Publication Agreements

• PI is Sponsor Employee: Yes

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: DOUBLE
• Who Masked: PARTICIPANT, OUTCOMES ASSESSOR
• Masking Details: Participants are not explicitly told they are in the control group, although they may deduce their assignment from presence or lack of regular text message intervention. Research staff doing data collection will not be aware of the random assignments and all participants will receive the same follow-up assessments regardless of assignment.
• Purpose: TREATMENT
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: June 4, 2021
• First Posted: June 9, 2021
• Study Start: October 1, 2021
• Primary Completion: October 18, 2023
• Study Completion: October 18, 2023
• Last Updated: March 12, 2025
• Results First Posted: March 12, 2025

Record last verified: 2025-02

Data Sharing

• IPD Sharing: Will not share

Locations

US (1)