Text Message Quit Vaping Intervention for Young Adults

NCT04251273 | Completed Results DMC

• 1 other identifier: TruthInitiativeQVS
• Study Type: interventional
• Target: 2,588
• Locations: 1 country
• Sites: 1

Brief Summary

This research study, conducted by Truth Initiative, will help us learn how text messaging can help young adults between 18 and 24 years of age quit vaping.

Conditions

Tobacco Cessation

Keywords

E-cigarette Cessation; Vaping Cessation; Mobile Intervention; Digital Intervention

Outcome Measures

Primary Outcomes (1)

• Number of Participants With Self-reported 30-day Point Prevalence Abstinence (ITT)

  Number of participant who responded "No" to the question "In the past 30 days, did you vape at all, even a puff of someone else's?" Denominator is all randomized participants.

  7 months post enrollment

Secondary Outcomes (3)

• Number of Participants With Self-reported 30-day Point Prevalence Abstinence (Responder Only)

  7 month post enrollment

• Number of Participants With Self-reported 7-day Point Prevalence Abstinence (ITT)

  7 months post enrollment

• Number of Participants With Self-reported 7-day Point Prevalence Abstinence (Responder Only)

  7 months post enrollment

Study Arms (2)

This is Quitting

EXPERIMENTAL

Participants will be enrolled to receive messages from This is Quitting. Users receive one age-appropriate message per day tailored to their enrollment date or quit date, which can be set and reset via text message. Those not ready to quit receive 4 weeks of messages focused on building skills and confidence. Users who set a quit date receive messages for a week preceding it and 8 weeks afterward that include encouragement and support, skill- and self-efficacy building exercises, coping strategies, and information about the risks of vaping, benefits of quitting, and cutting down to quit. Keywords COPE, STRESS, SLIP, and MORE provide on-demand support.

Other: This is Quitting

Assessment only Control

OTHER

After an initial enrollment message, participants will be contacted periodically to assess e-cigarette use. At the end of the intervention period, they will receive information on how to sign up for This is Quitting if they are interested in the program

Other: Assessment only Control

Interventions

This is Quitting OTHER

Text message-based intervention for quit vaping support.

This is Quitting

Assessment only Control OTHER

Assessment only

Assessment only Control

Eligibility Criteria

• Age: 18 Years - 24 Years
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64)

You may qualify if:

• Age 18-24
• Past 30-day use of e-cigarettes containing nicotine
• Interest in quitting e-cigarette use in the next 30 days
• US residence

You may not qualify if:

• Failure to confirm mobile number after initial sign-up

Sponsors & Collaborators

• Truth Initiative: lead

Study Sites (1)

Truth Initiative

Washington D.C., District of Columbia, 20001, United States

Location

Related Publications (4)

• Graham AL, Jacobs MA, Amato MS, Cha S, Bottcher MM, Papandonatos GD. Effectiveness of a Quit Vaping Text Message Program in Promoting Abstinence Among Young Adult E-Cigarette Users: Protocol for a Randomized Controlled Trial. JMIR Res Protoc. 2020 May 1;9(5):e18327. doi: 10.2196/18327.

  PMID: 32356774 BACKGROUND

• Graham AL, Cha S, Papandonatos GD, Amato MS, Jacobs MA, Abroms LC, Berg CJ. E-cigarette and combusted tobacco abstinence among young adults: Secondary analyses from a U.S.-based randomized controlled trial of vaping cessation. Prev Med. 2022 Dec;165(Pt B):107119. doi: 10.1016/j.ypmed.2022.107119. Epub 2022 Jun 28.

  PMID: 35777699 BACKGROUND

• Graham AL, Amato MS, Cha S, Jacobs MA, Bottcher MM, Papandonatos GD. Effectiveness of a Vaping Cessation Text Message Program Among Young Adult e-Cigarette Users: A Randomized Clinical Trial. JAMA Intern Med. 2021 Jul 1;181(7):923-930. doi: 10.1001/jamainternmed.2021.1793.

  PMID: 33999133 RESULT

• Graham AL, Cha S, Do EK, Jacobs MA, Edwards G, Papandonatos GD. Dual abstinence from nicotine vaping and cannabis use among young people: secondary analyses from two U.S.-based randomized controlled trials of vaping cessation. Subst Abuse Treat Prev Policy. 2025 Nov 3;20(1):48. doi: 10.1186/s13011-025-00679-1.

  PMID: 41177894 DERIVED

MeSH Terms

Conditions

Tobacco Use Cessation

Condition Hierarchy (Ancestors)

Health Behavior; Behavior

Results Point of Contact

• Title: Amanda L. Graham, PhD, Principal Investigator
• Organization: Truth Initiative

vapestudy@truthinitiative.org

(202) 525-6473‬

Study Officials

• Amanda L Graham, PhD

  Truth Initiative

  PRINCIPAL INVESTIGATOR

Publication Agreements

• PI is Sponsor Employee: Yes
• Restrictive Agreement: No

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: SINGLE
• Who Masked: PARTICIPANT
• Masking Details: Participants are not explicitly told they are in the control group, although they may deduce their assignment from presence or lack of regular text message intervention.
• Purpose: TREATMENT
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Chief of Innovations

Model Details: Arm 1: Intervention - Text message intervention Arm 2: Control - Assessment only

Study Record Dates

• First Submitted: January 23, 2020
• First Posted: January 31, 2020
• Study Start: December 19, 2019
• Primary Completion: November 12, 2020
• Study Completion: November 12, 2020
• Last Updated: July 10, 2024
• Results First Posted: February 14, 2023

Record last verified: 2024-06

Data Sharing

• IPD Sharing: Will not share

Locations

US (1)