The Effects of Three Different Ultrasound-guided Nerve Blocks in VATS
The Effects of Ultrasound-guided Mid-point Transverse Process to Pleura Block, Erector Spinae Plane Block and Paravertebral Block on Postoperative Pain in Video-assisted Thoracic Surgery
1 other identifier
interventional
90
1 country
1
Brief Summary
Ultrasound-guided mid-point transverse process to pleura block, erector spinae plane block and paravertebral block are three different methods of nerve block, used for relieving postoperative pain in thoracic anesthesia. This study is to compare them on block effects, postoperative pain and analgesic consumption in video-assisted thoracic surgery.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P50-P75 for not_applicable
Started Apr 2021
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
Click on a node to explore related trials.
Study Timeline
Key milestones and dates
First Submitted
Initial submission to the registry
March 30, 2021
CompletedFirst Posted
Study publicly available on registry
April 2, 2021
CompletedStudy Start
First participant enrolled
April 5, 2021
CompletedPrimary Completion
Last participant's last visit for primary outcome
October 1, 2022
CompletedStudy Completion
Last participant's last visit for all outcomes
December 1, 2022
CompletedApril 14, 2022
April 1, 2022
1.5 years
March 30, 2021
April 13, 2022
Conditions
Keywords
Outcome Measures
Primary Outcomes (1)
postoperative morphine consumption
The dose is according to the record from PCA pump
postoperative 24 hours
Secondary Outcomes (2)
Pain score at rest
at 0, 8, 24 hour after surgery
Pain score while coughing
at 0, 8, 24 hour after surgery
Other Outcomes (2)
block level
20 minutes after block
intraoperative analgesic comsumption
intraoperative, from induction to emergence from anesthesia
Study Arms (3)
paravertebral block
ACTIVE COMPARATORPatients receive ultrasound-guided paravertebral block
ESP block
ACTIVE COMPARATORPatients receive ultrasound-guided erector spinae plane (ESP) block
MTP block
EXPERIMENTALPatients receive ultrasound-guided mid-point transverse process to pleura (MTP) block
Interventions
Patients receive ultrasound-guided paravertebral block
Patients receive ultrasound-guided mid-point transverse process to pleura (MTP) block
Eligibility Criteria
You may qualify if:
- selective lobetomy under VATS
- ASA classfication 1-3
You may not qualify if:
- history of thoracic surgery
- double lateral VATS
- allergy to local anesthetics
- coagulation disorders
- severe heart diseases, hepatic or renal insufficiency
- a history of chronic pain or chronic opioid use
- psychiatric disease or uncooperative
- BMI\>28 kg/m2
- VATS transfered to open thoractomy
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Study Sites (1)
Tongji Hospital, Huazhong University of Science and Technology
Wuhan, Hubei, 430030, China
MeSH Terms
Conditions
Condition Hierarchy (Ancestors)
Study Officials
- STUDY CHAIR
Ailin Luo, MD,PhD
Tongji Hospital
Central Study Contacts
Study Design
- Study Type
- interventional
- Phase
- not applicable
- Allocation
- RANDOMIZED
- Masking
- TRIPLE
- Who Masked
- PARTICIPANT, INVESTIGATOR, OUTCOMES ASSESSOR
- Purpose
- TREATMENT
- Intervention Model
- PARALLEL
- Sponsor Type
- OTHER
- Responsible Party
- PRINCIPAL INVESTIGATOR
- PI Title
- Associate Professor
Study Record Dates
First Submitted
March 30, 2021
First Posted
April 2, 2021
Study Start
April 5, 2021
Primary Completion
October 1, 2022
Study Completion
December 1, 2022
Last Updated
April 14, 2022
Record last verified: 2022-04