Perception of Cure Among Patients With Metastatic Cancer

NCT04820894 | Withdrawn DMC

• 3 other identifiers: 19322NCI-2021-01818P30CA033572
• Study Type: observational
• Target: N/A
• Locations: 0 countries
• Sites: N/A

Brief Summary

This study collects information about perception of cure among patients with cancer that has spread to other places in the body (metastatic). This study aims to determine patients' perception (knowledge) before starting immunotherapy and if differences exist in understanding of treatment to stimulate or restore the ability of the body's immune (defense) system to fight infection and disease (immunotherapy) based on social and economic factors or on race/ethnicity.

Conditions

Hematopoietic and Lymphoid Cell Neoplasm; Metastatic Malignant Solid Neoplasm

Outcome Measures

Primary Outcomes (4)

• Percentage of patients

  Will assess the percentage of patients who anticipate cure before starting immunotherapy, scoring a '1' on the Perception of cure tool, and anticipate \>75% chance for a cure.

  Up to 2 years

• Patient Reported Outcomes Measurement Information System (PROMIS)

  Descriptive analyses (e.g. frequency statistics) will be used to characterize the sample and to look at the association between Patient Reported Outcomes Measurement Information System (PROMIS) tool score with perception of cure score.

  Up to 2 years

• Functional Assessment of Cancer Therapy-General (FACT-G)

  Descriptive analyses (e.g. frequency statistics) will be used to characterize the sample and to look at the association between Functional Assessment of Cancer Therapy-General (FACT-G) overall score with perception of cure score.

  Up to 2 years

• Perceptions of cure

  Chi-square analyses will be used to examine perceptions of cure by sociodemographic characteristics: gender (male and female), age (\< 60 and \> 60), and ethnicity (white non-Hispanic, Hispanic, and other).

  Up to 2 years

Study Arms (1)

Observational (survey, medical records review)

Patients complete surveys over 30 minutes about sociodemographic information and perception of immunotherapy, over 10 minutes about expectations of cure, over 10 minutes about anxiety, over 10 minutes about depression, and over 30 minutes about physical well-being. Patients' medical records are reviewed.

Other: Electronic Medical Record; Other: Survey Administration

Interventions

Electronic Medical Record OTHER

Medical records are reviewed

Also known as: Computer Based Patient Record, EMR, EMR (electronic medical record)

Observational (survey, medical records review)

Survey Administration OTHER

Complete surveys

Observational (survey, medical records review)

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

Patients with metastatic cancer

Eligibility Criteria: 1. Patients must be aged 18 and over 2. Patients sufficiently fluent in English 3. Patients must have a cytologically or pathologically verified diagnosis of cancer 4. Patients must have measurable metastatic disease 5. Patients must be initiating immunotherapy 6. Patients must be undergoing evaluation and treatment at City of Hope Cancer Center

Contact the study team to discuss eligibility requirements. They can help determine if this study is right for you.

Sponsors & Collaborators

• City of Hope Medical Center: lead
• National Cancer Institute (NCI): collaborator

MeSH Terms

Conditions

Hematologic Neoplasms; Neoplasm Metastasis

Interventions

Electronic Health Records

Condition Hierarchy (Ancestors)

Neoplasms by Site; Neoplasms; Hematologic Diseases; Hemic and Lymphatic Diseases; Neoplastic Processes; Pathologic Processes; Pathological Conditions, Signs and Symptoms

Intervention Hierarchy (Ancestors)

Medical Records Systems, Computerized; Medical Records; Records; Data Collection; Epidemiologic Methods; Investigative Techniques; Organization and Administration; Health Services Administration; Health Care Evaluation Mechanisms; Quality of Health Care; Health Care Quality, Access, and Evaluation; Public Health; Environment and Public Health

Study Officials

• Sumanta K Pal

  City of Hope Medical Center

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: March 25, 2021
• First Posted: March 29, 2021
• Study Start: October 30, 2021
• Primary Completion: January 5, 2022
• Study Completion: January 5, 2022
• Last Updated: May 23, 2025

Record last verified: 2025-05