Key Insights

Highlights

Success Rate

74% trial completion

Published Results

33 trials with published results (20%)

Clinical Risk Assessment

Based on trial outcomes

Moderate Risk

Score: 37/100

Termination Rate

8.0%

13 terminated out of 163 trials

Success Rate

74.0%

-12.5% vs benchmark

Late-Stage Pipeline

4%

6 trials in Phase 3/4

Results Transparency

89%

33 of 37 completed with results

Key Signals

33 with results74% success13 terminated

Data Visualizations

Phase Distribution

152Total
Not Applicable (15)
Early P 1 (4)
P 1 (96)
P 2 (31)
P 3 (4)
P 4 (2)

Trial Status

Recruiting48
Active Not Recruiting44
Completed37
Terminated13
Withdrawn11
Not Yet Recruiting6

Trial Success Rate

74.0%

Benchmark: 86.5%

Based on 37 completed trials

Clinical Trials (163)

Showing 20 of 20 trials
NCT07336238Phase 2Active Not Recruiting

Group Retreat Psilocybin Therapy for the Treatment of Anxiety and Depression in Patients With Metastatic Solid Tumors or Incurable Hematologic Malignancies

NCT05691491Phase 1Recruiting

Testing the Combination of the Anti-Cancer Drugs Temozolomide and M1774 to Evaluate Their Safety and Effectiveness

NCT05564377Phase 2Recruiting

Targeted Therapy Directed by Genetic Testing in Treating Patients With Locally Advanced or Advanced Solid Tumors, The ComboMATCH Screening Trial

NCT01366144Phase 1Active Not Recruiting

Veliparib, Paclitaxel, and Carboplatin in Treating Patients With Solid Tumors That Are Metastatic or Cannot Be Removed by Surgery and Liver or Kidney Dysfunction

NCT03030378Phase 1Active Not RecruitingPrimary

Pembrolizumab and Recombinant Interleukin-12 in Treating Patients With Solid Tumors

NCT04068194Phase 1Active Not Recruiting

Testing the Combination of New Anti-cancer Drug Peposertib With Avelumab and Radiation Therapy for Advanced/Metastatic Solid Tumors and Hepatobiliary Malignancies

NCT03284385Phase 2Active Not Recruiting

Testing AZD1775 in Advanced Solid Tumors That Have a Mutation Called SETD2

NCT05372614Phase 1RecruitingPrimary

Testing the Safety and Tolerability of the Anti-cancer Drugs Trastuzumab Deruxtecan and Neratinib for Cancers With Changes in the HER2 Gene

NCT02595931Phase 1Active Not Recruiting

M6620 and Irinotecan Hydrochloride in Treating Patients With Solid Tumors That Are Metastatic or Cannot Be Removed by Surgery

NCT01012817Phase 1Active Not RecruitingPrimary

Veliparib and Topotecan Hydrochloride in Treating Patients With Solid Tumors, Relapsed or Refractory Ovarian Cancer, or Primary Peritoneal Cancer

NCT05554380Phase 2Suspended

Study of Chemotherapy Plus Ipatasertib for People With Solid Tumors With PTEN/AKT Mutations, A ComboMATCH Treatment Trial

NCT03842228Phase 1Active Not Recruiting

Testing the Combination of the Anti-cancer Drugs Copanlisib, Olaparib, and MEDI4736 (Durvalumab) in Patients With Advanced Solid Tumors With Selected Mutations

NCT04387656Active Not Recruiting

NCI COVID-19 in Cancer Patients, NCCAPS Study

NCT04840589Phase 1SuspendedPrimary

Testing the Combination of ZEN003694 and Nivolumab With or Without Ipilimumab in Solid Tumors

NCT05372640Phase 1Recruiting

Testing the Safety and Efficacy of the Combination of Two Anti-cancer Drugs, ZEN003694 and Abemaciclib, for Adult and Pediatric Patients (12-17 Years) With Metastatic or Unresectable NUT Carcinoma, Breast Cancer and Other Solid Tumors

NCT03872427Phase 2Active Not Recruiting

Testing Whether Cancers With Specific Mutations Respond Better to Glutaminase Inhibitor, Telaglenastat Hydrochloride, Anti-Cancer Treatment, BeGIN Study

NCT05803382Phase 1Recruiting

Testing the Addition of an Anti-Cancer Drug, ZEN003694, to the Usual Chemotherapy Treatment (Capecitabine) for Metastatic or Unresectable Cancers

NCT04585958Phase 1RecruitingPrimary

Testing the Combination of DS-8201a and Olaparib in HER2-Expressing Cancers With Expansion in Patients With Platinum Resistant Ovarian Cancer

NCT04514497Phase 1Active Not Recruiting

Testing the Addition of an Anti-cancer Drug, BAY 1895344, to Usual Chemotherapy for Advanced Stage Solid Tumors, With a Specific Focus on Patients With Small Cell Lung Cancer, Poorly Differentiated Neuroendocrine Cancer, and Pancreatic Cancer

NCT06076135Phase 2CompletedPrimary

Intestinal Low Dose Radiotherapy Combined With Immunotherapy in Immune-resistant Metastatic Solid Tumors

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