NCT04792450

Brief Summary

COVID Related Study. This study will compare the Thales High Temperature Detection (HTD) system with the two routinely used temperature measurement systems (tympanic and forehead) in patients and staff in the Emergency Department. The aims of the study are:

  • To determine the diagnostic accuracy of HTD for the measurement of fever, using an equivalence comparison with the maximum temperature recorded with two routinely used temperature measurements (tympanic and forehead), margin ±0.2°C.
  • To determine if skin tone is an independent confounding factor in the measurement of fever using HTD
  • To establish performance of internal calibration of Thales device
  • To power for a definitive Clinical Investigation to determine clinical efficacy and safety cut off with HTD If results are encouraging the aim would then be to undertake a clinical investigation in order to get CE marking for use in a clinical setting.

Trial Health

43
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
200

participants targeted

Target at P75+ for all trials

Timeline
Completed

Started Nov 2020

Shorter than P25 for all trials

Geographic Reach
1 country

1 active site

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

September 25, 2020

Completed
1 month until next milestone

Study Start

First participant enrolled

November 1, 2020

Completed
1 month until next milestone

Primary Completion

Last participant's last visit for primary outcome

December 15, 2020

Completed
3 months until next milestone

First Posted

Study publicly available on registry

March 11, 2021

Completed
2 months until next milestone

Study Completion

Last participant's last visit for all outcomes

May 1, 2021

Completed
Last Updated

March 11, 2021

Status Verified

March 1, 2021

Enrollment Period

1 month

First QC Date

September 25, 2020

Last Update Submit

March 7, 2021

Conditions

Outcome Measures

Primary Outcomes (1)

  • To determine the diagnostic accuracy of HTD for the measurement of fever, using an equivalence comparison with the maximum temperature recorded with two routinely used temperature measurements (tympanic and forehead), margin ±0.2°C.

    Measurement of temperature in celsius

    First 4 hours of hospitalisation.

Study Arms (2)

ED Patients

Patients presenting in Emergency Department

Device: ThermographyDevice: Tympanic ThermometerDevice: Forehead ThermometerDevice: 62 Max + Infra-red thermometer

ED Staff

Staff working within the Emergency Department

Device: ThermographyDevice: Tympanic ThermometerDevice: Forehead ThermometerDevice: 62 Max + Infra-red thermometer

Interventions

Measure Temperature using Thermal Camera

ED PatientsED Staff

Measure Temperature using Tympanic Thermometer

ED PatientsED Staff

Measure Temperature using Forehead Temperature

ED PatientsED Staff

Measure Temperature using 62 Max + Infra-red thermometer

ED PatientsED Staff

Eligibility Criteria

Age16 Years+
Sexall
Healthy VolunteersYes
Age GroupsChild (0-17), Adult (18-64), Older Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

All patients attending Queen Elizabeth University Hospital Emergency Department requiring triage. All staff members working within Queen Elizabeth University Hospital Emergency Department.

You may qualify if:

  • Patients ≥ 16 years old with no upper age limit
  • Patients able to read and understand English
  • Patients able to give informed consent
  • Patients being triaged through ED for any complaint, not necessarily COVID-19 QEUH ED staff

You may not qualify if:

  • Patients who do not have capacity to consent
  • Patients attending ED who are fast-tracked without triage

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Queen Elizabeth University Hospital

Glasgow, G52 4TF, United Kingdom

Location

MeSH Terms

Conditions

Fever

Interventions

Thermography

Condition Hierarchy (Ancestors)

Body Temperature ChangesSigns and SymptomsPathological Conditions, Signs and Symptoms

Intervention Hierarchy (Ancestors)

Diagnostic ImagingDiagnostic Techniques and ProceduresDiagnosisThermometryInvestigative Techniques

Study Design

Study Type
observational
Observational Model
COHORT
Time Perspective
PROSPECTIVE
Target Duration
1 Day
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Dr David J Lowe

Study Record Dates

First Submitted

September 25, 2020

First Posted

March 11, 2021

Study Start

November 1, 2020

Primary Completion

December 15, 2020

Study Completion

May 1, 2021

Last Updated

March 11, 2021

Record last verified: 2021-03

Data Sharing

IPD Sharing
Will not share

Locations