Dual-Task Zumba Gold for Improving the Cognition of Older Adults With MCI

NCT04788238 | Unknown

• 1 other identifier: HSEARS20200717002
• Study Type: interventional
• Target: 60
• Locations: 1 country
• Sites: 1

Brief Summary

The study aims to assess the preliminary efficacy of a Dual-Task Zumba Gold (DTZ) intervention that will support physical and cognitive training among community-dwelling persons with mild cognitive impairment (MCI). A 12-week Dual-Task Zumba Gold (DTZ) intervention will be implemented among 30 participants with MCI in the treatment group, while health education will be provided to another 30 subjects allocated in the control group. Changes in global cognitive function, together with the quality of life, mood, functional mobility, and bodily measures, will be re-assessed after the 12-week intervention and a 6-week follow-up period. Quantitative and qualitative methods will also be employed to assess the feasibility and acceptability outcomes of the study.

Conditions

Mild Cognitive Impairment

Keywords

dual-task; Zumba Gold; mild cognitive impairment; dementia risk reduction

Outcome Measures

Primary Outcomes (5)

• Changes in Montreal Cognitive Assessment score (from baseline to 18 weeks follow-up)

  Montreal Cognitive Assessment (MoCA) evaluates global cognition by involving multiple domains such as attention, memory, language, visuospatial skills, abstraction, calculation, and orientation. The scores range from 0 to 30, with higher scores indicating better cognitive performance.

  Baseline; 12 weeks; 18 weeks

• Changes in Trail Making Test Part A (from baseline to 18 weeks follow-up)

  Trail Making Test Part A is a time-based examination that requires individuals to connect randomly arranged numbers following the correct sequence. The time limit for this test is up to 150 seconds, and shorter duration pertains to better processing speed.

  Baseline; 12 weeks; 18 weeks

• Changes in Trail Making Test Part B (from baseline to 18 weeks follow-up)

  Trail Making Test Part B is a time-based examination that requires individuals to connect randomly arranged numbers and letters following the correct and alternating sequence. The time limit for this test is up to 300 seconds, and shorter duration pertains to better executive function.

  Baseline; 12 weeks; 18 weeks

• Changes in Digit Span test (from baseline to 18 weeks follow-up)

  In Digit Span Test, numbers are read to the participant at a rate of one per second and then later asked to repeat them in a forward and backward manner. Scores range from 0 - 14 and higher scores indicate better short-term memory.

  Baseline; 12 weeks; 18 weeks

• Changes in the MoCA-Memory Index score (from baseline to 18 weeks follow-up)

  The Memory Index Score of the Montreal Cognitive Assessment (MoCA-MIS) ranges from 0-15, which is based on free delayed recall, category cued recall, and multiple choice cued recall. Higher scores indicate better delayed recall ability.

  Baseline; 12 weeks; 18 weeks

Secondary Outcomes (6)

• Changes in quality of life using Perceived Well-Being Scale (from baseline to 18 weeks follow-up)

  Baseline; 12 weeks; 18 weeks

• Changes in mood using Geriatric Depression Scale-Short Form (from baseline to 18 weeks follow-up)

  Baseline; 12 weeks; 18 weeks

• Changes in functional mobility using Short Physical Performance Battery (from baseline to 18 weeks follow-up)

  Baseline; 12 weeks; 18 weeks

• Changes in blood pressure (from baseline to 18 weeks follow-up)

  Baseline; 12 weeks; 18 weeks

• Changes in body-mass index (from baseline to 18 weeks follow-up)

  Baseline; 12 weeks; 18 weeks

Study Arms (2)

Intervention group

EXPERIMENTAL

Participants in the intervention arm will participate in the dual-task Zumba Gold (DTZ) program. They will be grouped into 10 participants per class.

Behavioral: Dual-Task Zumba Gold

Control group

NO INTERVENTION

Participants in the control group will receive health education about dementia risk reduction provided by community health nurses.

Interventions

Dual-Task Zumba Gold BEHAVIORAL

Dual-Task Zumba Gold is a 12-week program to be conducted thrice weekly for 45-60 minutes. The intervention involves the concurrent performance of cognitive tasks and physical movements during specific parts of the dance. The activity will begin with warm-up and end with cool-down periods, at 5 to 10 minutes each. Orientation training will be done during the warm-up period, by asking questions to participants about time, place, and person. In the actual dance (30 to 40 minutes), the following domains will be trained: executive function (forward and backward serial counting); perceptual-motor ability (performing arm clock positions based on instructions); memory (forward and backward repetition of number/word series), and attention (forward and backward spelling of 3- to 5-letter words). The cool-down period will incorporate memory training by reminding the participants to summarize the activities performed.

Intervention group

Eligibility Criteria

• Age: 55 Years - 80 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• subjective report/concern about changes in memory or cognition
• objective cognitive impairment, based on Montreal Cognitive Assessment (MoCA) score of ≤25
• absence of diagnosis of dementia or Alzheimer's disease
• normal function in daily activities, via Katz ADL scale score of 6
• ambulatory, without the need to use assistive devices
• able to read/communicate in the Filipino/English language

You may not qualify if:

• medical diagnosis of any form of neurological or psychiatric disorder
• uncontrolled or severe heart condition, cancer, major musculoskeletal disorder, psychiatric condition, serious hearing/visual impairment, or any condition that would limit study safety; or being at risk for adverse events to PA participation, assessed via the revised Physical Activity Readiness Questionnaire (rPARQ)
• intake of medications such as anti-depressants, sedatives, or anti-epileptics that may affect cognition
• participation in any organized physical activity program in the past 3 months

Sponsors & Collaborators

• The Hong Kong Polytechnic University: lead

Study Sites (1)

Municipality of Plaridel

Plaridel, Bulacan, 3004, Philippines

Location

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  BACKGROUND

• Parial LL, Kor PPK, Sumile EF, Leung AYM. Dual-Task Zumba Gold for Improving the Cognition of People With Mild Cognitive Impairment: A Pilot Randomized Controlled Trial. Gerontologist. 2023 Aug 24;63(7):1248-1261. doi: 10.1093/geront/gnac081.

  PMID: 35679826 DERIVED

MeSH Terms

Conditions

Cognitive Dysfunction

Condition Hierarchy (Ancestors)

Cognition Disorders; Neurocognitive Disorders; Mental Disorders

Study Officials

• Angela Leung, PhD

  The Hong Kong Polytechnic University

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: SINGLE
• Who Masked: OUTCOMES ASSESSOR
• Masking Details: Outcome assessors and data analysts will be blinded to the group allocation until the whole data analyses are completed. They will also not be involved in any part of the treatment administration. Furthermore, participants will be advised not to disclose their group assignment during data collection.
• Purpose: SUPPORTIVE CARE
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Associate Professor

Model Details: Participants will be equally allocated to the intervention and control group, following a randomization schedule generated by an independent statistician who has no access to the subjects. The randomization list will be sealed in sequentially numbered opaque envelopes. Participants will be informed of the group allocation after the submission of written consent and completion of the baseline assessments.

Study Record Dates

• First Submitted: February 25, 2021
• First Posted: March 9, 2021
• Study Start: March 29, 2021
• Primary Completion: October 15, 2021
• Study Completion: August 31, 2022
• Last Updated: February 4, 2022

Record last verified: 2022-01

Data Sharing

• IPD Sharing: Will not share

Locations

PH (1)