NCT04754919

Brief Summary

Study into the use of a diabetes specialist transition nurse in the care of young people aged 16-20 years, with type 1 diabetes; undergoing transition from the paediatric to the adult diabetes services at the Northampton General Hospital

Trial Health

43
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
100

participants targeted

Target at P50-P75 for not_applicable

Timeline
Completed

Started Dec 2018

Typical duration for not_applicable

Geographic Reach
1 country

1 active site

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

December 1, 2018

Completed
9 months until next milestone

First Submitted

Initial submission to the registry

August 22, 2019

Completed
1.5 years until next milestone

First Posted

Study publicly available on registry

February 15, 2021

Completed
9 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

November 1, 2021

Completed
2 months until next milestone

Study Completion

Last participant's last visit for all outcomes

January 1, 2022

Completed
Last Updated

February 15, 2021

Status Verified

February 1, 2021

Enrollment Period

2.9 years

First QC Date

August 22, 2019

Last Update Submit

February 12, 2021

Conditions

Outcome Measures

Primary Outcomes (1)

  • The rates of diabetes related hospital episodes, including Diabetic Ketoacidosis, between the 2 study groups before and after transition

    Rates of admission

    3 years

Secondary Outcomes (5)

  • The mean Hba1C between the 2 study groups before and after transition

    3 years

  • The frequency of testing according to National Institute for Health and Care Excellence between the 2 study groups

    3 years

  • Emotional health of the 2 study groups

    3 years

  • Emotional health of the 2 study groups

    3 years

  • To compare the proportion of young people in the study groups who fail to attend at least one out-patient adult diabetes appointment during the first year after transition

    3 years

Study Arms (2)

Transition intervention group

ACTIVE COMPARATOR

Intervention group -will be working with the specialist diabetes transition nurse. The nurse will follow a specific protocol involving visits, clinic support, community support and appointment rearranging. She will also maintain communication with the Hospital based adult and paediatric diabetes teams and the participants General Practitioner and relevant community health care professionals.

Other: Transition intervention group

Post Transition group

PLACEBO COMPARATOR

The previous fifty eligible young people who have transitioned to adult service, will be compared with the active comparator group.

Other: Post transition group

Interventions

Support and on-going treatment intervention; monitoring the uptake of routine annual diabetes tests and encouraging to access where default observed General specialist diabetes support and provision of education and referral to other specialist healthcare agencies as individual requires

Transition intervention group

The previous fifty eligible young people who have transitioned to adult service, will be compared with the active comparator group.

Post Transition group

Eligibility Criteria

Age16 Years - 20 Years
Sexall
Healthy VolunteersYes
Age GroupsChild (0-17), Adult (18-64)

You may qualify if:

  • established type 1 diabetes for minimum of 1 year
  • attended the Northampton general Hospital, children's and young peoples diabetes service for at least 6 months prior to transition
  • between the ages of 16 - 20 years
  • ability to participate in all aspects of the trial
  • written informed consent must be obtained

You may not qualify if:

  • any condition which may interfere with the subjects ability to participate in the study including cystic-fibrosis related diabetes
  • subjects who move away from the Northampton General Hospital clinic during the transition process
  • those unable to give informed consent

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Northampton general Hospital NHS Trust

Northampton, NN1 5BD, United Kingdom

Location

Related Publications (2)

  • Crowley R, Wolfe I, Lock K, McKee M. Improving the transition between paediatric and adult healthcare: a systematic review. Arch Dis Child. 2011 Jun;96(6):548-53. doi: 10.1136/adc.2010.202473. Epub 2011 Mar 8.

  • Spaic T, Mahon JL, Hramiak I, Byers N, Evans K, Robinson T, Lawson ML, Malcolm J, Goldbloom EB, Clarson CL; JDRF Canadian Clinical Trial CCTN1102 Study Group. Multicentre randomized controlled trial of structured transition on diabetes care management compared to standard diabetes care in adolescents and young adults with type 1 diabetes (Transition Trial). BMC Pediatr. 2013 Oct 9;13:163. doi: 10.1186/1471-2431-13-163.

Related Links

MeSH Terms

Conditions

Diabetes Mellitus, Type 1

Condition Hierarchy (Ancestors)

Diabetes MellitusGlucose Metabolism DisordersMetabolic DiseasesNutritional and Metabolic DiseasesEndocrine System DiseasesAutoimmune DiseasesImmune System Diseases

Study Officials

  • Anne L Smith, MBChB

    Northampton General Hospital

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
NON RANDOMIZED
Masking
NONE
Purpose
SUPPORTIVE CARE
Intervention Model
SINGLE GROUP
Model Details: Next 50 eligible young people entering transition
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Consultant Paediatrician

Study Record Dates

First Submitted

August 22, 2019

First Posted

February 15, 2021

Study Start

December 1, 2018

Primary Completion

November 1, 2021

Study Completion

January 1, 2022

Last Updated

February 15, 2021

Record last verified: 2021-02

Data Sharing

IPD Sharing
Will not share

There is no plan to share individual participant data, with other researchers

Locations