Different Low-flow Sevoflurane Anesthesia Techniques

NCT04743193 | Completed

• 1 other identifier: 2020-514-169-13
• Study Type: observational
• Target: 60
• Locations: 1 country
• Sites: 1

Brief Summary

After reaching 1 MAC level with 4 lt / min fresh gas flow and 2.5% sevoflurane concentration in the initial stage in 35 patients, anesthesia maintenance will be continued with 0.5 lt / min fresh gas flow and 2 -4% sevoflurane concentration with the target of 1 MAC. For 35 patients, after reaching 1 (MAC) level with 1 lt / min fresh gas flow and 8% sevoflurane concentration in the initial phase, maintenance of anesthesia will be continued with 0.5 lt / min fresh gas flow and 2 -4% sevoflurane concentration, targeting 1 MAC.

Conditions

Anesthesia

Keywords

inhalation

Outcome Measures

Primary Outcomes (1)

• sevoflurane versus desflurane

  To compare the instant and total consumption of sevoflurane using 2 different concentrations and different minute / fresh gas flow to fill the system in the initial phase of anesthesia.

  the study will comlete in one month

Secondary Outcomes (1)

• sevoflurane

  studdy will complete in one month

Study Arms (2)

sevoflurane 8 %

In the initial phase, after reaching 1 (MAK) level with 1lt / min fresh gas flow and 8% sevoflurane concentration, anesthesia maintenance will be continued with 0.5 lt / min fresh gas flow and 2 -4% sevoflurane concentration with the target of 1 MAC.

Other: 8% sevoflurane low flow anesthesia

sevoflurane 2.5 %

In the initial phase, after reaching 1 MAK level with 4 lt / min fresh gas flow and 2.5% sevoflurane concentration, anesthesia maintenance will be continued with 0.5 lt / min fresh gas flow and 2 -4% sevoflurane concentration with the target of 1 MAC.

Other: 2.5 %sevoflurane

Interventions

2.5 %sevoflurane OTHER

for 35 patients after reaching 1 MAK level with 4 lt / min fresh gas flow and 2,5% sevoflurane concentration in the initial phase, maintenance of anesthesia will be continued with 0.5 lt / min fresh gas flow and 2 -4% sevoflurane concentration with the target of 1 minimum alveolar concentration

sevoflurane 2.5 %

8% sevoflurane low flow anesthesia OTHER

For 35 patients after reaching 1 (MAC) level with 1 lt / min fresh gas flow and 8% sevoflurane concentration in the initial phase, maintenance of anesthesia will be continued with 0.5 lt / min fresh gas flow and 2 -4% sevoflurane concentration, targeting 1 MAC. .

sevoflurane 8 %

Eligibility Criteria

• Age: 18 Years - 65 Years
• Sex: all
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

* Patients between the ages of 18-65 * ASA1,2,3 group patients

You may qualify if:

• Patients between the ages of 18-65
• ASA1,2,3 group patients
• Patients under general anesthesia
• Patients scheduled for elective surgery

You may not qualify if:

• The patient's refusal to participate in the study
• Patients with less than 90 minutes of total anesthesia time
• Patients whose total anesthesia time exceeds 180 minutes

Sponsors & Collaborators

• Kocaeli Derince Education and Research Hospital: lead

Study Sites (1)

Tahsin Şimşek

Istanbul, Kartal, 34000, Turkey (Türkiye)

Location

MeSH Terms

Conditions

Respiratory Aspiration

Condition Hierarchy (Ancestors)

Respiration Disorders; Respiratory Tract Diseases; Pathologic Processes; Pathological Conditions, Signs and Symptoms

Study Design

• Study Type: observational
• Observational Model: OTHER
• Time Perspective: PROSPECTIVE
• Target Duration: 1 Day
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: principal investigator

Study Record Dates

• First Submitted: February 2, 2021
• First Posted: February 8, 2021
• Study Start: February 5, 2021
• Primary Completion: April 28, 2021
• Study Completion: May 15, 2021
• Last Updated: September 1, 2021

Record last verified: 2021-08

Locations

TU (1)