Tricuapid Annular Plane Sistolic Excursion Before General Anesthesia Can Predict Hypotension After Induction

NCT04580030 | Unknown

• 1 other identifier: 2020-6/1
• Study Type: observational
• Target: 7
• Locations: 1 country
• Sites: 1

Brief Summary

the investigators purpose is to predict hypotensive condition that can develop after general anesthesia induction by measuring the Tricuspid Annular Plane Systolic Movement (TAPSE), which is an echocardiographic parameter.

Conditions

Anesthesia

Keywords

General anesthesia; tricuspid anular plane systolic excursion; hypotension

Outcome Measures

Primary Outcomes (1)

• tricuspid anular plane systolic excursion(TAPSE)

  The investigators purpose is to predict hypotensive condition that can develop after general anesthesia induction by measuring the Tricuspid Annular Plane Systolic Movement (TAPSE), which is an echocardiographic parameter.

  TAPSE will be measured with Transthoracic Echocardiography about 30 minutes before the induction in the preoperative period.

Study Arms (2)

hypotension

Basal hemodynamic parameters and hemodynamic values will be taken every two minutes after induction until surgical incision. Patients with systolic pressure \<90 mmHg or 30% drop in baseline, and mean artery pressure below 60 mmHg will be considered to have hypotension. Patients will be divided into two groups as "Hypotension" and "No Hypotension".

no hypotension

Basal hemodynamic parameters and hemodynamic values will be taken every two minutes after induction until surgical incision. Patients with systolic pressure \<90 mmHg or 30% drop in baseline, and mean artery pressure below 60 mmHg will be considered to have hypotension. Patients will be divided into two groups as "Hypotension" and "No Hypotension".

Eligibility Criteria

• Age: 18 Years - 65 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Probability Sample

Study Population

It was planned that a total of 40 patients undergoing elective general surgery under general anesthesia with standard general anesthesia induction would be included in this prospective and observational study.

You may qualify if:

• Patients scheduled for elective surgery
• Patients who will receive general anesthesia
• Patients between 18-65 years of age
• Physical status I or II according to the American Society of Anesthetists (ASA) in preoperative evaluation
• Those without known heart disease
• Patients with TAPSE value above 1.6 cm

You may not qualify if:

• Patients under the age of 8 and over 65,
• Pregnant patients,
• Patients who refuse to participate in the study,
• ASA III and above,
• Patients with known heart disease,
• Patients with TAPSE value of less than 1.6 measured with Transthoracic Echocardiography will not be allowed to be included in the study.
• Patients with difficult airway management or difficult intubation will be excluded from the study.

Sponsors & Collaborators

• Bursa City Hospital: lead

Study Sites (1)

Bursa City Hospital

Bursa, Turkey (Türkiye)

Location

Related Publications (3)

• Zhang J, Critchley LA. Inferior Vena Cava Ultrasonography before General Anesthesia Can Predict Hypotension after Induction. Anesthesiology. 2016 Mar;124(3):580-9. doi: 10.1097/ALN.0000000000001002.

  PMID: 26771910 BACKGROUND

• Szabo M, Bozo A, Darvas K, Horvath A, Ivanyi ZD. Role of inferior vena cava collapsibility index in the prediction of hypotension associated with general anesthesia: an observational study. BMC Anesthesiol. 2019 Aug 7;19(1):139. doi: 10.1186/s12871-019-0809-4.

  PMID: 31390983 RESULT

• Main AB, Braham R, Campbell D, Inglis AJ, McLean A, Orde S. Subcostal TAPSE: a retrospective analysis of a novel right ventricle function assessment method from the subcostal position in patients with sepsis. Ultrasound J. 2019 Aug 27;11(1):19. doi: 10.1186/s13089-019-0134-7.

  PMID: 31456096 RESULT

MeSH Terms

Conditions

Hypotension

Condition Hierarchy (Ancestors)

Vascular Diseases; Cardiovascular Diseases

Study Officials

• Ferdi Gülaştı

  Bursa City Hospital

  STUDY CHAIR

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER GOV
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: M.D. Specialist of anesthesiology and reanimation

Study Record Dates

• First Submitted: October 2, 2020
• First Posted: October 8, 2020
• Study Start: September 9, 2020
• Primary Completion: September 9, 2021
• Study Completion: September 10, 2021
• Last Updated: October 20, 2020

Record last verified: 2020-10

Data Sharing

• IPD Sharing: Will share
• Shared Documents: STUDY PROTOCOL, SAP, ICF, CSR, ANALYTIC CODE

Locations

TU (1)