Low Fresh Gas Flow in Prone Position
Low Fresh Gas Flow and Normal Gas Flow Anesthesia in Patients Undergoing Surgery in Prone Position: Impact on Hemodynamics and Regional Cerebral Oxygenation
1 other identifier
interventional
46
1 country
1
Brief Summary
Low flow anesthesia in the prone position was safe in terms of systemic hemodynamics and did not reduce cerebral oxygenation compared to normal flow.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P25-P50 for not_applicable
Started Oct 2019
Shorter than P25 for not_applicable
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
Click on a node to explore related trials.
Study Timeline
Key milestones and dates
Study Start
First participant enrolled
October 1, 2019
CompletedPrimary Completion
Last participant's last visit for primary outcome
March 31, 2020
CompletedStudy Completion
Last participant's last visit for all outcomes
March 31, 2020
CompletedFirst Submitted
Initial submission to the registry
July 6, 2022
CompletedFirst Posted
Study publicly available on registry
July 18, 2022
CompletedJuly 18, 2022
July 1, 2022
6 months
July 6, 2022
July 14, 2022
Conditions
Keywords
Outcome Measures
Primary Outcomes (1)
Low and Normal Fresh Gas Flow Difference in Prone Position
Whether low flow anesthesia in the prone position is safe in terms of systemic hemodynamics and cerebral oxygenation compared to normal flow anesthesia
Systemic and cerebral oxygenation values were measured 10 minutes after induction to general anesthesia and followed up to 10 minutes were left to completion of the surgery for about 5 hours, which may vary according to the duration of the surgery.
Study Arms (2)
Low Fresh Gas Flow in Prone Position
EXPERIMENTALLow fresh gas flow (0,5 L/min during maintenance)
Normal Fresh Gas Flow in Prone Position
ACTIVE COMPARATORNormal flow (2 L/min) in general anesthesia.
Interventions
In the low fresh gas flow group, the flow rate was reduced to 0.5 L/min
In the normal flow rate group, the gas flow rate was reduced to 2 L/min during the maintenance phase.
Eligibility Criteria
You may qualify if:
- undergoing surgery in the prone position
- having an American Society of Anesthesiologists (ASA) physical status I to III
- willingness to participate in the study
You may not qualify if:
- having a Glasgow coma scale (GSC) score ≤ 12
- previous history of cranial surgery
- advanced cardiovascular and/or pulmonary disease
- mental retardation
- neurological disease
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Study Sites (1)
Prof. Dr. Cemil Tascioglu City Hospital
Istanbul, Sisli, 34384, Turkey (Türkiye)
MeSH Terms
Interventions
Intervention Hierarchy (Ancestors)
Study Design
- Study Type
- interventional
- Phase
- not applicable
- Allocation
- RANDOMIZED
- Masking
- NONE
- Purpose
- SCREENING
- Intervention Model
- PARALLEL
- Sponsor Type
- OTHER
- Responsible Party
- PRINCIPAL INVESTIGATOR
- PI Title
- Medical Doctor
Study Record Dates
First Submitted
July 6, 2022
First Posted
July 18, 2022
Study Start
October 1, 2019
Primary Completion
March 31, 2020
Study Completion
March 31, 2020
Last Updated
July 18, 2022
Record last verified: 2022-07