NCT06598852

Brief Summary

Comparison of analgesic effects of ultrasound-guided thoracic paravertebral block, erector spinae muscle block, thoracic paravertebral block combined with erector spinae muscle block, and intercostal nerve block in thoracoscopic surgery

Trial Health

57
Monitor

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
120

participants targeted

Target at P50-P75 for not_applicable

Timeline
Completed

Started Sep 2024

Shorter than P25 for not_applicable

Geographic Reach
1 country

1 active site

Status
recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

September 12, 2024

Completed
3 days until next milestone

Study Start

First participant enrolled

September 15, 2024

Completed
4 days until next milestone

First Posted

Study publicly available on registry

September 19, 2024

Completed
2 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

November 20, 2024

Completed
2 months until next milestone

Study Completion

Last participant's last visit for all outcomes

January 20, 2025

Completed
Last Updated

December 2, 2024

Status Verified

August 1, 2024

Enrollment Period

2 months

First QC Date

September 12, 2024

Last Update Submit

November 28, 2024

Conditions

Postoperative Analgesia

Keywords

thoracic paravertebral nerve blockerectoralis muscle blockintercostal nerve block

Outcome Measures

Primary Outcomes (1)

  • Postoperative pain score

    Visual analogue scale (VAS) was used to evaluate the degree of pain 1h (T1), 24h (T2) and 48h (T3) after surgery, the number of effective analgesic pump compressions and the number of remedial analgesia within 48h after surgery.

    48 hours after surgery

Secondary Outcomes (1)

  • Incidence of postoperative complications

    48 hours after surgery

Study Arms (4)

TPVB group

EXPERIMENTAL

Ultrasound-guided thoracic paravertebral nerve block was used for postoperative analgesia after thoracic surgery

Other: TPVB group

ESPB group

EXPERIMENTAL

Ultrasound-guided erector spinae muscle block was used for postoperative analgesia after thoracic surgery

Other: ESPB group

TPVB combined ESPB group

EXPERIMENTAL

Ultrasound-guided thoracic paravertebral nerve block combined with erector spinae muscle block was used for postoperative analgesia after thoracic surgery

Other: TPVB combined ESPB group

ICNB group

EXPERIMENTAL

Intercostal nerve block was used for postoperative analgesia after thoracic surgery

Other: ICNB group

Interventions

TPVB groupOTHER

Patients undergoing thoracoscopic surgery underwent general anesthesia and patients in TPVB Group received thoracic paravertebral nerve block with 0.33% ropivacaine 30ml under ultrasound guidance after anesthesia induction for postoperative analgesia.

TPVB group
ESPB groupOTHER

Patients undergoing thoracoscopic surgery underwent general anesthesia and patients in ESPB Group received erector spinae muscle block with 0.33% ropivacaine 30ml under ultrasound guidance after anesthesia induction for postoperative analgesia.

ESPB group
TPVB combined ESPB groupOTHER

Patients undergoing thoracoscopic surgery underwent general anesthesia and patients in TPVB combined ESPB group received thoracic paravertebral block combined with erector spinae muscle block with 0.33% ropivacaine 30ml under ultrasound guidance after anesthesia induction for postoperative analgesia.

TPVB combined ESPB group
ICNB groupOTHER

Patients undergoing thoracoscopic surgery underwent general anesthesia and patients in ICNB Group received intercostal nerve block for postoperative analgesia.

ICNB group

Eligibility Criteria

Age18 Years - 70 Years
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • (1) American Society of Anesthesiologists (ASA) Grade I-II; (2) Age: 18-70 years old (3) double-hole thoracic surgery was performed; (4) Agree to participate in this study and sign the informed consent.

You may not qualify if:

  • (1) People who are allergic to anesthetics used in this study; (2) Patients with coagulation disorders (3) patients with severe heart disease, liver or renal insufficiency; (4) have a history of chronic pain or chronic opioid users (5) have a co-existing mental illness and are not fully capable of cooperating

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

First hospital of Qinhuangdao

Qinhuangdao, Hebei, 066000, China

RECRUITING

Study Officials

  • Zhuo Liu

    The First hosptial of Qinhuangdao

    STUDY DIRECTOR

Central Study Contacts

Ximing Qi

CONTACT

+86-13731777660qhdddyyykyc@163.com

Zhuo Liu

CONTACT

+86-18330357618liuzhuo2011@yeah.net

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
DOUBLE
Who Masked
PARTICIPANT, OUTCOMES ASSESSOR
Purpose
PREVENTION
Intervention Model
PARALLEL
Sponsor Type
OTHER GOV
Responsible Party
SPONSOR

Study Record Dates

First Submitted

September 12, 2024

First Posted

September 19, 2024

Study Start

September 15, 2024

Primary Completion

November 20, 2024

Study Completion

January 20, 2025

Last Updated

December 2, 2024

Record last verified: 2024-08

Locations

CN(1)