NCT04644224

Brief Summary

This study tests the effectiveness of parent and family oriented support interventions that are designed to help with weight loss among African American families. Obesity tends to run in families, thus family based interventions, with parents as main change agents have been strongly recommended. The parent and family oriented support Interventions may help facilitate weight loss among African American families.

Trial Health

75
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
81

participants targeted

Target at P50-P75 for not_applicable

Timeline
32mo left

Started Jan 2019

Longer than P75 for not_applicable

Geographic Reach
1 country

1 active site

Status
active not recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

Study Progress73%
Jan 2019Dec 2028

Study Start

First participant enrolled

January 17, 2019

Completed
1.8 years until next milestone

First Submitted

Initial submission to the registry

October 21, 2020

Completed
1 month until next milestone

First Posted

Study publicly available on registry

November 25, 2020

Completed
8.1 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

December 31, 2028

Expected
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

December 31, 2028

Last Updated

January 9, 2026

Status Verified

January 1, 2026

Enrollment Period

10 years

First QC Date

October 21, 2020

Last Update Submit

January 7, 2026

Conditions

Outcome Measures

Primary Outcomes (6)

  • Weight loss of parents

    Will use the generalized linear mixed model (GLMM) regression, which takes into account both within-cluster (e.g., within church) and, as applicable, within-individual (e.g., overtime) correlations between observations of each primary and secondary outcomes of interest.

    Up to 18 months

  • Reach (Part 1 of the RE-AIM framework)

    Measured as the number of churches invited to participate, number enrolled, and differences between the two groups.

    Up to 18 months

  • Effectiveness (Part 2 of the RE-AIM framework)

    Measured as the impact on weight loss: 6 focus groups and 15 individual interviews at 18 months to understand unanticipated outcomes; interview lay health workers (LHWs) about implementation.

    Up to 18 months

  • Adoption (Part 3 of the RE-AIM framework)

    Will be measured by asking churches about factors that helped or hindered adoption or implementation and will they adopt intervention when completed.

    Up to 18 months

  • Implementation (Part 4 of the RE-AIM framework)

    Measured as study attendance and assessments, number of health coaching, LHW and support group sessions, number of staff training, and self-monitoring practices.

    Up to 18 months

  • Maintenance (Part 5 of the RE-AIM framework)

    Long-term maintenance in parent/families at 18 months measured by family and church attrition, to assess church's ability to maintain employment of LHWs and their willingness to remain in this role.

    Up to 18 months

Secondary Outcomes (6)

  • Child's body mass index (BMI) z-score

    Up to 18 months

  • Fruit and vegetable consumption

    Up to 18 months

  • Physical activity

    Up to 18 months

  • Blood pressure

    Up to 18 months

  • Body fat percentage

    Up to 18 months

  • +1 more secondary outcomes

Study Arms (3)

Group I (coaching session, navigation session, support group)

EXPERIMENTAL

Parents/caregivers whose churches are randomized to Group I, attend monthly health coaching sessions over 1 hour each for 12 months, 9 resource navigation sessions over 12 months, and monthly support groups for 12 months.

Other: Educational ActivityOther: Educational InterventionOther: Questionnaire AdministrationProcedure: Support Group Therapy

Group II (coaching session, navigation session, support group)

EXPERIMENTAL

Families whose churches are randomized to Group II, attend monthly health coaching sessions over 1 hour each for 12 months, 9 resource navigation sessions over 12 months, and monthly support groups for 12 months.

Other: Educational ActivityOther: Educational InterventionOther: Questionnaire AdministrationProcedure: Support Group Therapy

Group III (educational handbook)

ACTIVE COMPARATOR

Families whose churches are randomized to Group III, receive an educational handbook on cancer prevention.

Other: Informational InterventionOther: Questionnaire Administration

Interventions

Attend health coaching session

Group I (coaching session, navigation session, support group)Group II (coaching session, navigation session, support group)

Attend resource navigation session

Also known as: Education for Intervention, Intervention by Education, Intervention through Education, Intervention, Educational
Group I (coaching session, navigation session, support group)Group II (coaching session, navigation session, support group)

Receive handbook

Group III (educational handbook)

Ancillary studies

Group I (coaching session, navigation session, support group)Group II (coaching session, navigation session, support group)Group III (educational handbook)

Attend support group

Group I (coaching session, navigation session, support group)Group II (coaching session, navigation session, support group)

Eligibility Criteria

Age10 Years - 65 Years
Sexall
Healthy VolunteersYes
Age GroupsChild (0-17), Adult (18-64), Older Adult (65+)

You may qualify if:

  • DYAD: Be parent/caregiver (legal parent or custodial grandparent; male or female) and child willing to participate
  • DYAD: Live together in the same household
  • PARENT/CAREGIVER: Self-identify as a racial ethic minority (i.e., black or African American or Hispanic)
  • PARENT/CAREGIVER: Parent or caregiver age 18 through 65 years old
  • PARENT/CAREGIVER: Are overweight (BMI greater than or equal to 25);
  • PARENT/CAREGIVER: Are not currently participating in a physical activity (PA), diet, or weight management program
  • PARENT/CAREGIVER: Have a valid home address, telephone number, and internet access
  • PARENT/CAREGIVER: Enroll with a child aged 8-17 years
  • PARENT/CAREGIVER: Are able to speak English

You may not qualify if:

  • PARENT/CAREGIVER: They are currently pregnant or thinking about becoming pregnant during the study period
  • PARENT/CAREGIVER: They present any contraindications for exercise based on responses to the PA Readiness Questionnaire plus (PAR-Q +)
  • \) None.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

M D Anderson Cancer Center

Houston, Texas, 77030, United States

Location

Related Links

MeSH Terms

Interventions

Early Intervention, EducationalEducational StatusMethods

Intervention Hierarchy (Ancestors)

Child Health ServicesCommunity Health ServicesHealth ServicesHealth Care Facilities Workforce and ServicesPreventive Health ServicesSocioeconomic FactorsPopulation CharacteristicsInvestigative Techniques

Study Officials

  • Lorna McNeill

    M.D. Anderson Cancer Center

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
NONE
Purpose
PREVENTION
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

October 21, 2020

First Posted

November 25, 2020

Study Start

January 17, 2019

Primary Completion (Estimated)

December 31, 2028

Study Completion (Estimated)

December 31, 2028

Last Updated

January 9, 2026

Record last verified: 2026-01

Locations