NCT04614155

Brief Summary

This trial studies if Project Self can improve the rate of cervical cancer screening in Hispanic and African American women living in Houston, Texas. Project Self may help to improve cervical cancer screening rates by providing human papillomavirus (HPV) self-collection kits, education, counseling, and navigation.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
40

participants targeted

Target at P25-P50 for not_applicable

Timeline
Completed

Started Aug 2019

Longer than P75 for not_applicable

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

August 27, 2019

Completed
1.2 years until next milestone

First Submitted

Initial submission to the registry

October 26, 2020

Completed
8 days until next milestone

First Posted

Study publicly available on registry

November 3, 2020

Completed
4.8 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

August 8, 2025

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

August 8, 2025

Completed
Last Updated

August 12, 2025

Status Verified

August 1, 2025

Enrollment Period

6 years

First QC Date

October 26, 2020

Last Update Submit

August 11, 2025

Conditions

Outcome Measures

Primary Outcomes (2)

  • Participant consent rate

    Up to 1 month

  • Human papillomavirus (HPV) self-collection uptake rate

    Defined as the proportion of the participants who consent to the study and receive an HPV self-collection kit complete the self-collection and return the sample to the lab or research staff member or community health worker within timeline.

    Up to 2 weeks after health education session

Secondary Outcomes (3)

  • Cervical screening associated knowledge, attitudes and practices score

    Up to 1 month

  • Participants' self-reported Pap smear screening rate in last 3 years

    Up to 1 month

  • HPV positive proportion

    Up to 1 month

Study Arms (1)

Screening (questionnaire, health education, self-collection)

EXPERIMENTAL

Participants complete questionnaires, take part in a health education session, and receive HPV self-collection kit.

Other: Educational InterventionProcedure: HPV Self-CollectionOther: Questionnaire Administration

Interventions

Take part in health education session

Also known as: Education for Intervention, Intervention by Education, Intervention through Education, Intervention, Educational
Screening (questionnaire, health education, self-collection)

Receive HPV self-collection kit

Also known as: At-home HPV Self Collection, HPV Self Collection, Human Papillomavirus Self-Collection
Screening (questionnaire, health education, self-collection)

Complete questionnaires

Screening (questionnaire, health education, self-collection)

Eligibility Criteria

Age30 Years - 65 Years
Sexfemale
Healthy VolunteersYes
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Self-identify as African American or Hispanic women.
  • Valid home address reflective of residence in the participating housing development(s) at least 50% of the time.
  • Functioning telephone number.
  • Speak and read English or Spanish.

You may not qualify if:

  • Self-reported hysterectomy.
  • Self-reported personal history of cancer/cancer diagnosis.
  • Self-reported as pregnant.
  • Another household member is enrolled in this protocol.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

M D Anderson Cancer Center

Houston, Texas, 77030, United States

Location

Related Publications (1)

  • Shastri SS, McNeill LH, Shete S. Culturally Competent Education and Human Papillomavirus Self-Sampling Achieves Healthy People 2030 Cervical Screening Target Among Low-Income Non-Hispanic Black and Hispanic Women. JCO Glob Oncol. 2024 May;10:e2400005. doi: 10.1200/GO.24.00005.

Related Links

MeSH Terms

Interventions

Early Intervention, EducationalEducational StatusMethods

Intervention Hierarchy (Ancestors)

Child Health ServicesCommunity Health ServicesHealth ServicesHealth Care Facilities Workforce and ServicesPreventive Health ServicesSocioeconomic FactorsPopulation CharacteristicsInvestigative Techniques

Study Officials

  • Surendranath S Shastri

    M.D. Anderson Cancer Center

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
NA
Masking
NONE
Purpose
SCREENING
Intervention Model
SINGLE GROUP
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

October 26, 2020

First Posted

November 3, 2020

Study Start

August 27, 2019

Primary Completion

August 8, 2025

Study Completion

August 8, 2025

Last Updated

August 12, 2025

Record last verified: 2025-08

Locations