Eat, Move, Live Program for the Reduction of Cancer and Chronic Disease Risk in Underserved Communities

NCT05414396 | Active Not Recruiting DMC

• 3 other identifiers: 17410NCI-2022-00180P30CA033572
• Study Type: interventional
• Target: 347
• Locations: 1 country
• Sites: 1

Brief Summary

This clinical trial tests the Eat, Move, Live (EML) Program in reducing the risk of chronic diseases among underserved communities by improving healthy lifestyle practices, increasing physical activity and encouraging healthy eating behaviors. EML is a series of free culturally and linguistically appropriate nutrition and physical activity sessions. The interactive education segment of the EML Program is culturally responsive, and based on the community EML program, and topics will include: nutrition guidelines, reading food labels, recipe modification and healthy food preparation, eating healthy on a budget, chronic diseases information and prevention strategies. The EML program may help reduce the risk of cancer and chronic diseases by encouraging more physical activity and healthy eating behaviors.

Conditions

Diabetes Mellitus; Obesity-Related Malignant Neoplasm

Outcome Measures

Primary Outcomes (15)

• Changes in attitudes and beliefs as measured by questionnaires from baseline to week 12

  Attitudes and beliefs regarding causes of diabetes asked in questionnaire, measured by endorsing one of the Likert-type scale values ranging from 1 (Agree) to 7 (Disagree).

  Baseline and week 12

• Changes in behavior as measured by questionnaires from baseline to week 12

  Behaviors related to food consumption asked in questionnaires, measured by endorsing one of "None", "1", "2-3", "4-6", "7 or more".

  Baseline and week 12

• Changes in height from baseline to week 12

  Height measured in meters

  Baseline to 12 weeks

• Changes in weight from baseline to week 12

  Weight measured in Kilograms

  Baseline to 12 weeks

• Changes in waist circumference from baseline to week 12

  Hip circumference measured in centimeters

  Baseline to 12 weeks

• Changes in chest circumference from baseline to week 12

  Chest circumference measured in centimeters

  Baseline to 12 weeks

• Changes in right upper arm circumference from baseline to week 12

  Right upper arm circumference measured in centimeters

  Baseline to 12 weeks

• Changes in left upper arm circumference from baseline to week 12

  Left upper arm circumference measured in centimeters

  Baseline to 12 weeks

• Changes in right upper thigh circumference from baseline to week 12

  Right upper thigh circumference measured in centimeters

  Baseline to 12 weeks

• Changes in left upper thigh circumference from baseline to week 12

  Left upper thigh circumference measured in centimeters

  Baseline to 12 weeks

• Changes in body fat percentage from baseline to week 12

  Body fat percentage measured in percent using a handheld BMI machine that calculates body fat percentage.

  Baseline to 12 weeks

• Changes in systolic blood pressure from baseline to week 12

  Systolic blood pressure measured in mmHG

  Baseline to 12 weeks

• Changes in diastolic blood pressure from baseline to week 12

  Diastolic blood pressure measured in mmHG

  Baseline to 12 weeks

• Changes in hip circumference from baseline to week 12

  Hip circumference measured in centimeters

  Baseline to 12 weeks

• Changes in biomarkers

  Will be collected at baseline and follow up based on glycosylated hemoglobin (A1C) measuring guidelines.

  Baseline to 12 weeks

Study Arms (1)

Supportive care (EML program)

EXPERIMENTAL

Participants attend EML program sessions weekly for 12 weeks including an educational session chronic disease risk reduction via nutrition and physical activity, a physical activity session, and a cooking/taste test demonstration.

Behavioral: Behavioral Intervention; Other: Questionnaire Administration

Interventions

Behavioral Intervention BEHAVIORAL

Attend EML program sessions

Also known as: Behavior Conditioning Therapy, Behavior Modification, Behavior or Life Style Modifications, Behavior Therapy, Behavioral Interventions, Behavioral Modification, Behavioral Therapy, Behavioral Treatment, Behavioral Treatments

Supportive care (EML program)

Questionnaire Administration OTHER

Ancillary studies

Supportive care (EML program)

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• Agrees to group consent at week 1
• Age over 18
• Able to speak and understand English and/or Spanish

You may not qualify if:

• Don't agree to group consent at week 1
• Age younger than 18
• Not able to speak and understand English and/or Spanish
• Can't participate in physical activity

Sponsors & Collaborators

• City of Hope Medical Center: lead
• National Cancer Institute (NCI): collaborator

Study Sites (1)

City of Hope Medical Center

Duarte, California, 91010, United States

Location

MeSH Terms

Conditions

Diabetes Mellitus

Interventions

Behavior Therapy

Condition Hierarchy (Ancestors)

Glucose Metabolism Disorders; Metabolic Diseases; Nutritional and Metabolic Diseases; Endocrine System Diseases

Intervention Hierarchy (Ancestors)

Psychotherapy; Behavioral Disciplines and Activities

Study Officials

• Victoria L Seewaldt

  City of Hope Medical Center

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: NA
• Masking: NONE
• Purpose: SUPPORTIVE CARE
• Intervention Model: SINGLE GROUP
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: March 24, 2022
• First Posted: June 10, 2022
• Study Start: March 20, 2018
• Primary Completion (Estimated): October 12, 2026
• Study Completion (Estimated): October 12, 2026
• Last Updated: December 5, 2025

Record last verified: 2025-12

Locations

US (1)