Handgrip Training With and Without Blood Flow Restriction in Relation to Gender Among Healthy Young Adults

NCT04606654 | Completed

• 1 other identifier: REC/788 Arva Naeem
• Study Type: interventional
• Target: 56
• Locations: 1 country
• Sites: 1

Brief Summary

In this study Investigator will determine the effects of blood flow restriction training on hand grip strength using hand held dynamometer among healthy young adults and investigator also see effects of blood flow restriction training on forearm circumference using weighted measuring tape among healthy young adults along with correlation of male and female population following blood flow restriction training among healthy young adults.

Conditions

Sports Physical Therapy

Outcome Measures

Primary Outcomes (2)

• Hand grip strength

  Changes from the baseline, To measure hand grip strength through Hydraulic Hand held Dynamo-meter. It will be measured in pounds

  8 weeks

• Forearm circumference

  After strength training forearm circumference through anthropometric measuring tape will be measured in inches by inches measuring tape.

  8 weeks

Study Arms (2)

Handgrip strength training with Blood flow restriction

EXPERIMENTAL

Three sessions per week will be given to individual subject. and training will be with Blood flow restriction. Subjects will be followed for two weeks for; * Hand grip strength * Forearm circumference

Other: Handgrip strength training with Blood flow restriction

Handgrip strength training without Blood flow restriction

ACTIVE COMPARATOR

Three sessions per week will be given to individual subject and training will be without Blood flow restriction. Subjects will be followed for two weeks for; * Hand grip strength * Forearm circumference

Other: Handgrip strength training without Blood flow restriction

Interventions

Handgrip strength training without Blood flow restriction OTHER

Participants of this group will get exercise training through hand grip strengthener and DMOOSE fitness resistance bar. Participants will contract his/her forearm at a rate of 15 times/min (1 contraction every 4 sec). The subjects will train for 20 min, 3 days per week for 2 weeks (total 6 sessions), under the supervision of a principle investigator. Participants will be allowed to take 1 min rest periods, after the completion of 5 minutes of training.

Handgrip strength training without Blood flow restriction

Handgrip strength training with Blood flow restriction OTHER

Participants of this group will get exercise training through hand grip strengthener and DMOOSE fitness resistance bar. Participants will contracts his/her forearm at a rate of 15 times/min (1 contraction every 4 sec). The subjects will train for 20 min, 3 days per week for 2 weeks (total 6 sessions), under the supervision of a principle investigator. Participants will be allowed to take 1 min rest periods, after the completion of 5 minutes of training. However, for one of the limbs the pneumatic blood pressure cuff will be placed on the upper arm, 4 cm proximal to the ante-cubital fossa. The decision which arm would receive the occlusion during training will be randomized to avoid a dominant or non-dominant hand bias. During experimental group training blood pressure cuff will be partially inflated (80 mmHg) to ensure venous occlusion. Participants will be allowed to take 1 min rest periods, after the completion of 5 minutes of training while the cuff remained inflated.

Handgrip strength training with Blood flow restriction

Eligibility Criteria

• Age: 20 Years - 40 Years
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64)

You may qualify if:

• Healthy adults of sedentary lifestyle
• Young healthy adults following 6 minutes' Walk test
• Young healthy adults following YMCA 3 minutes Step test

You may not qualify if:

• Any diagnosed cardiovascular, metabolic, orthopaedic or neurological disease
• Active/ongoing infection
• Recent history of upper extremity fracture
• History of vascular medication

Sponsors & Collaborators

• Riphah International University: lead

Study Sites (1)

Foundation University Institute of Rehabilitation Sciences

Rawalpindi, Punjab Province, 44000, Pakistan

Location

Related Publications (17)

• Hughes L, Paton B, Rosenblatt B, Gissane C, Patterson SD. Blood flow restriction training in clinical musculoskeletal rehabilitation: a systematic review and meta-analysis. Br J Sports Med. 2017 Jul;51(13):1003-1011. doi: 10.1136/bjsports-2016-097071. Epub 2017 Mar 4.

  PMID: 28259850 BACKGROUND

• Lixandrao ME, Ugrinowitsch C, Berton R, Vechin FC, Conceicao MS, Damas F, Libardi CA, Roschel H. Magnitude of Muscle Strength and Mass Adaptations Between High-Load Resistance Training Versus Low-Load Resistance Training Associated with Blood-Flow Restriction: A Systematic Review and Meta-Analysis. Sports Med. 2018 Feb;48(2):361-378. doi: 10.1007/s40279-017-0795-y.

  PMID: 29043659 BACKGROUND

• Cristina-Oliveira M, Meireles K, Spranger MD, O'Leary DS, Roschel H, Pecanha T. Clinical safety of blood flow-restricted training? A comprehensive review of altered muscle metaboreflex in cardiovascular disease during ischemic exercise. Am J Physiol Heart Circ Physiol. 2020 Jan 1;318(1):H90-H109. doi: 10.1152/ajpheart.00468.2019. Epub 2019 Nov 8.

  PMID: 31702969 BACKGROUND

• Pearson SJ, Hussain SR. A review on the mechanisms of blood-flow restriction resistance training-induced muscle hypertrophy. Sports Med. 2015 Feb;45(2):187-200. doi: 10.1007/s40279-014-0264-9.

  PMID: 25249278 BACKGROUND

• Sato, Y., The history and future of KAATSU training. International Journal of KAATSU Training Research, 2005. 1(1): p. 1-5.

  BACKGROUND

• Yasuda, T., et al., Use and safety of KAATSU training: Results of a national survey in 2016. International Journal of KAATSU Training Research, 2017. 13(1): p. 1-9.

  BACKGROUND

• O'Brien, L. Blood Flow Restriction Therapy. 2020 [cited 2020; Available from: https://members.physio-pedia.com/learn/blood-flow-restriction-therapy/.

  BACKGROUND

• Cardoso RK, Araujo AM, Del Vechio FB, Bohlke M, Barcellos FC, Oses JP, de Freitas MP, Rombaldi AJ. Intradialytic exercise with blood flow restriction is more effective than conventional exercise in improving walking endurance in hemodialysis patients: a randomized controlled trial. Clin Rehabil. 2020 Jan;34(1):91-98. doi: 10.1177/0269215519880235. Epub 2019 Oct 11.

  PMID: 31603002 BACKGROUND

• Jessee MB, Dankel SJ, Buckner SL, Mouser JG, Mattocks KT, Loenneke JP. The Cardiovascular and Perceptual Response to Very Low Load Blood Flow Restricted Exercise. Int J Sports Med. 2017 Jul;38(8):597-603. doi: 10.1055/s-0043-109555. Epub 2017 Jun 26.

  PMID: 28651256 BACKGROUND

• Brandner CR, Kidgell DJ, Warmington SA. Unilateral bicep curl hemodynamics: Low-pressure continuous vs high-pressure intermittent blood flow restriction. Scand J Med Sci Sports. 2015 Dec;25(6):770-7. doi: 10.1111/sms.12297. Epub 2014 Jul 23.

  PMID: 25055880 BACKGROUND

• Araujo JP, Silva ED, Silva JC, Souza TS, Lima EO, Guerra I, Sousa MS. The acute effect of resistance exercise with blood flow restriction with hemodynamic variables on hypertensive subjects. J Hum Kinet. 2014 Nov 12;43:79-85. doi: 10.2478/hukin-2014-0092. eCollection 2014 Sep 29.

  PMID: 25713647 BACKGROUND

• Centner C, Wiegel P, Gollhofer A, Konig D. Correction to: Effects of Blood Flow Restriction Training on Muscular Strength and Hypertrophy in Older Individuals: A Systematic Review and Meta-Analysis. Sports Med. 2019 Jan;49(1):109-111. doi: 10.1007/s40279-018-1013-2.

  PMID: 30414044 BACKGROUND

• Jacobson, J., et al., Blood Flow Restriction Training in Clinical Musculoskeletal Rehabilitation: A Critically Appraised Paper. International Journal of Athletic Therapy and Training, 2020. 1(aop): p. 1-4.

  BACKGROUND

• Pope ZK, Willardson JM, Schoenfeld BJ. Exercise and blood flow restriction. J Strength Cond Res. 2013 Oct;27(10):2914-26. doi: 10.1519/JSC.0b013e3182874721.

  PMID: 23364292 BACKGROUND

• Credeur DP, Hollis BC, Welsch MA. Effects of handgrip training with venous restriction on brachial artery vasodilation. Med Sci Sports Exerc. 2010 Jul;42(7):1296-302. doi: 10.1249/MSS.0b013e3181ca7b06.

  PMID: 20019641 BACKGROUND

• https://www.sralab.org/. 6 Minute Walk Test. 2020 2020 [cited 2020; Available from: https://www.sralab.org/rehabilitation-measures/6-minute-walk-test.

  BACKGROUND

• Bohannon RW, Bubela DJ, Wang YC, Magasi SS, Gershon RC. Six-Minute Walk Test Vs. Three-Minute Step Test for Measuring Functional Endurance. J Strength Cond Res. 2015 Nov;29(11):3240-4. doi: 10.1519/JSC.0000000000000253.

  PMID: 24077375 BACKGROUND

Study Officials

• Suhail Karim, PP-DPT

  Riphah International University

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: DOUBLE
• Who Masked: PARTICIPANT, INVESTIGATOR
• Purpose: TREATMENT
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: October 22, 2020
• First Posted: October 28, 2020
• Study Start: August 1, 2020
• Primary Completion: February 5, 2021
• Study Completion: February 5, 2021
• Last Updated: February 8, 2021

Record last verified: 2021-02

Data Sharing

• IPD Sharing: Will not share

Locations

PA (1)