NCT04576624

Brief Summary

With population aging, the number of older persons with cognitive impairments increases. Literature support the effectiveness of a lifestyle approach to promote the health of persons with cognitive impairment, as well as a Lifestyle Redesign intervention to improve the general health and quality of life of frail older adults. The investigators propose to combine a multi-modal cognitive intervention and lifestyle redesign approach to improve the cognitive health of older persons with cognitive impairments.

Trial Health

43
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
125

participants targeted

Target at P50-P75 for not_applicable

Timeline
Completed

Started Aug 2020

Typical duration for not_applicable

Geographic Reach
1 country

1 active site

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

August 1, 2020

Completed
1 month until next milestone

First Submitted

Initial submission to the registry

September 8, 2020

Completed
28 days until next milestone

First Posted

Study publicly available on registry

October 6, 2020

Completed
2.8 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

July 31, 2023

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

July 31, 2023

Completed
Last Updated

October 6, 2020

Status Verified

September 1, 2020

Enrollment Period

3 years

First QC Date

September 8, 2020

Last Update Submit

September 29, 2020

Conditions

Keywords

lifestyle interventionbrain healthagingcognitive impairment

Outcome Measures

Primary Outcomes (9)

  • Cognitive function

    Montreal Cognitive Assessment, with a value of 0-30. Higher scores mean a better outcome.

    pre-intervention

  • Cognitive function

    Montreal Cognitive Assessment, with a value of 0-30. Higher scores mean a better outcome.

    6 months after the intervention begins

  • Cognitive function

    Montreal Cognitive Assessment, with a value of 0-30. Higher scores mean a better outcome.

    6 month after the end of intervention

  • Activity participation

    Canadian Performance of Occupational Performance, with a value of 0-10. Higher scores mean a better outcome.

    pre-intervention

  • Activity participation

    Canadian Performance of Occupational Performance, with a value of 0-10. Higher scores mean a better outcome.

    6 months after the intervention begins

  • Change of activity participation

    Canadian Performance of Occupational Performance, with a value of 0-10. Higher scores mean a better outcome.

    6 month after the end of intervention

  • QOL (Quality of Life)

    COOP/WONCA is the full title of the assessment. The assessment has a value of 6-30. Higher scores mean a poorer outcome.

    pre-intervention

  • QOL (Quality of Life)

    COOP/WONCA is the full title of the assessment. The assessment has a value of 6-30. Higher scores mean a poorer outcome.

    6 months after the intervention begins

  • QOL (Quality of Life)

    COOP/WONCA is the full title of the assessment. The assessment has a value of 6-30. Higher scores mean a poorer outcome.

    6 month after the end of intervention

Secondary Outcomes (15)

  • Physical function

    pre-intervention

  • Physical function

    6 months after the intervention begins

  • Physical function

    6 month after the end of intervention

  • Functional memory

    pre-intervention

  • Functional memory

    6 months after the intervention begins

  • +10 more secondary outcomes

Study Arms (3)

Lifestyle Intervention

EXPERIMENTAL

Subjects in the Lifestyle Intervention group will, in six months, receive sixteen group sessions and six individualized treatment sessions.

Behavioral: Lifestyle Intervention

Social Activities

SHAM COMPARATOR

Social Activities Group will receive twenty-two group sessions

Behavioral: social activity

Passive Control

NO INTERVENTION

Control group will receive patient education materials with each assessment

Interventions

A combined approach of a lifestyle structuring intervention to improve the general health and quality of life of persons with cognitive impairments. The investigators propose to combine a multi-modal cognitive intervention and lifestyle redesign approach to improve the cognitive health of older persons with cognitive impairments.

Lifestyle Intervention
social activityBEHAVIORAL

24 social gathering events

Social Activities

Eligibility Criteria

Age50 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Over 55 years old and living in the community
  • Reported cognitive declines.

You may not qualify if:

  • Within normal cognition, determined by scoring more than 24 in the Taiwanese version of the Montreal Cognitive Assessment
  • Having any medical, neurological, psychiatric conditions, and depression by scoring above 10 in the Brief Symptom Rating Scale
  • Having severe visual, auditory, speech or physical problems that limit them to follow instructions.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

National Cheng-Kung University

Tainan, 701, Taiwan

RECRUITING

MeSH Terms

Conditions

Cognitive Dysfunction

Condition Hierarchy (Ancestors)

Cognition DisordersNeurocognitive DisordersMental Disorders

Study Officials

  • Ling-Hui Chang

    Department of Occupational Therapy, NCKU

    PRINCIPAL INVESTIGATOR

Central Study Contacts

Ling Hui Chang, Ph.D

CONTACT

Study Design

Study Type
interventional
Phase
not applicable
Allocation
NON RANDOMIZED
Masking
TRIPLE
Who Masked
PARTICIPANT, CARE PROVIDER, OUTCOMES ASSESSOR
Purpose
TREATMENT
Intervention Model
PARALLEL
Model Details: three-year project using a combined pragmatic randomized controlled clinical trial and multiple case studies mixed-method research design
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Associate Professor

Study Record Dates

First Submitted

September 8, 2020

First Posted

October 6, 2020

Study Start

August 1, 2020

Primary Completion

July 31, 2023

Study Completion

July 31, 2023

Last Updated

October 6, 2020

Record last verified: 2020-09

Data Sharing

IPD Sharing
Will not share

Locations