Home Based Tele-exercise for People With Chronic Neurological Impairments

NCT04564495 | Active Not Recruiting

• 1 other identifier: Telex
• Study Type: interventional
• Target: 60
• Locations: 1 country
• Sites: 1

Brief Summary

To assess the impact of a 12-week virtual seated physical intervention on cardiovascular health and wellness in people with chronic neurological impairments (CNI).

Conditions

Neurologic Disorder; Stroke; Spinal Cord Injuries; Cerebral Palsy; Hemiplegia; Hemiparesis; Multiple Sclerosis; Parkinson Disease; Trauma, Brain; Transverse Myelitis; Friedreich Ataxia

Outcome Measures

Primary Outcomes (1)

• Change in heart rate

  Heart rate on last day of training compared to heart rate on first day of training

  Within one week before the first intervention session to within one week after the end of intervention

Secondary Outcomes (6)

• Perceived Wellness Survey

  Within one week before the first intervention session to within one week after the end of intervention

• Physical Activity Enjoyment Scale

  Within one week before the first intervention session to within one week after the end of intervention

• Short Form-36 Health Survey

  Within one week before the first intervention session to within one week after the end of intervention

• Numerical pain rating

  Within one week before the first intervention session to within one week after the end of intervention

• Borg's Rating Scale of Perceived Exertion

  Within one week before the first intervention session to within one week after the end of intervention

Study Arms (2)

Live zoom exercise classes

EXPERIMENTAL

Participants will engage in a live zoom exercise session. Participants will undergo 45 minutes of aerobic exercise intervention, three times a week, for a period of 12 weeks. Exercise will include repetitive bouts of high intensity exercises with intermittent periods of rest or active recovery. circuit of moves like 'jabs', 'hooks' etc, and a strength and endurance class that promotes postural awareness.

Behavioral: Seated exercise

Recorded zoom exercise classes

ACTIVE COMPARATOR

Participants will undergo 45 minutes of aerobic exercise intervention, three times a week, for a period of 12 weeks, using a pre-recorded class that they can do according to their own schedule. Exercise will include repetitive bouts of high intensity exercises with intermittent periods of rest or active recovery. circuit of moves like 'jabs', 'hooks' etc, and a strength and endurance class that promotes postural awareness.

Behavioral: Seated exercise

Interventions

Seated exercise BEHAVIORAL

Exercise will include repetitive bouts of high intensity exercises with intermittent periods of rest or active recovery. circuit of moves like 'jabs', 'hooks' etc, and a strength and endurance class that promotes postural awareness.

Live zoom exercise classes; Recorded zoom exercise classes

Eligibility Criteria

• Age: 18 Years - 75 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• Participants with chronic (\>6 months) neurological impairments
• to 75 years of age
• Participants who can provide a medical clearance to participate in the program
• Participants who can remain seated for at least one hour
• Heart rate/BP considerations, per each participant's MD
• Participants must be able to don/doff HR monitor without assistance, or have assistance if necessary
• Participants must maintain their current exercise/physical activity routine during the course of the study
• Clinically stable with no other neurological, medical or cognitive impairments
• Reliable Internet connection and ability to use Zoom platform
• Participants must speak and understand English
• No contraindication/limitations to exercise
• Currently exercising 2 days or less per week

You may not qualify if:

• Participants with any cognitive impairment preventing safe and accurate participation in the program
• Medical issues preventing safe participation
• Other problems possibly contraindicating autonomous exercise at home if no supervision available.

Sponsors & Collaborators

• Burke Medical Research Institute: lead

Study Sites (1)

Burke Neurological Institute

White Plains, New York, 10605, United States

Location

Related Publications (2)

• Kumar DS, Bialek A, Divecha AA, Garn RM, Currie LEJ, Friel KM. A seated virtual exercise program to improve cardiovascular function in adults with chronic neurological impairments: a randomized controlled trial. Front Rehabil Sci. 2025 Mar 26;6:1477969. doi: 10.3389/fresc.2025.1477969. eCollection 2025.

  PMID: 40207026 DERIVED

• Divecha AA, Bialek A, Kumar DS, Garn RM, Currie LEJ, Campos T, Friel KM. Effects of a 12-week, seated, virtual, home-based tele-exercise programme compared with a prerecorded video-based exercise programme in people with chronic neurological impairments: protocol for a randomised controlled trial. BMJ Open. 2023 Jan 24;13(1):e065032. doi: 10.1136/bmjopen-2022-065032.

  PMID: 36693691 DERIVED

MeSH Terms

Conditions

Nervous System Diseases; Stroke; Spinal Cord Injuries; Cerebral Palsy; Hemiplegia; Paresis; Multiple Sclerosis; Parkinson Disease; Brain Injuries, Traumatic; Myelitis, Transverse; Friedreich Ataxia

Condition Hierarchy (Ancestors)

Cerebrovascular Disorders; Brain Diseases; Central Nervous System Diseases; Vascular Diseases; Cardiovascular Diseases; Spinal Cord Diseases; Trauma, Nervous System; Wounds and Injuries; Brain Damage, Chronic; Paralysis; Neurologic Manifestations; Signs and Symptoms; Pathological Conditions, Signs and Symptoms; Demyelinating Autoimmune Diseases, CNS; Autoimmune Diseases of the Nervous System; Demyelinating Diseases; Autoimmune Diseases; Immune System Diseases; Parkinsonian Disorders; Basal Ganglia Diseases; Movement Disorders; Synucleinopathies; Neurodegenerative Diseases; Brain Injuries; Craniocerebral Trauma; Myelitis; Central Nervous System Infections; Infections; Paraneoplastic Syndromes, Nervous System; Nervous System Neoplasms; Neoplasms by Site; Neoplasms; Paraneoplastic Syndromes; Neuroinflammatory Diseases; Spinocerebellar Degenerations; Cerebellar Diseases; Heredodegenerative Disorders, Nervous System; Genetic Diseases, Inborn; Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Mitochondrial Diseases; Metabolic Diseases; Nutritional and Metabolic Diseases

Study Officials

• Kathleen Friel

  Burke Medical Research Institute

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: NONE
• Purpose: TREATMENT
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Model Details: One group will attend live zoom classes with instructor feedback, and the other group will exercise using pre-recorded sessions.

Study Record Dates

• First Submitted: September 23, 2020
• First Posted: September 25, 2020
• Study Start: January 22, 2021
• Primary Completion: December 31, 2023
• Study Completion: May 31, 2025
• Last Updated: February 5, 2025

Record last verified: 2025-02

Data Sharing

• IPD Sharing: Will share
• Shared Documents: STUDY PROTOCOL, SAP, ICF
• Time Frame: These types of supporting information will be published as a protocol paper, and will remain accessible with no end date.

Locations

US (1)