Quadratus Lumborum Block Versus Transversus Abdominis Plane Block for Postoperative Analgesia in Children

NCT04552548 | Completed

• 1 other identifier: 271:7/2019
• Study Type: interventional
• Target: 90
• Locations: 1 country
• Sites: 1

Brief Summary

The aim of the present study is to evaluate and compare the analgesic effect of ultrasound-guided Quadratus Lumborum Block with ultrasound-guided Transversus Abdominis plane block in pediatric Laparoscopic lower abdominal surgeries

Conditions

Postoperative Pain

Outcome Measures

Primary Outcomes (1)

• quality of postoperative analgesia

  Postoperative Pain scores as FLACC score (face, legs, activity, cry and consolability)

  24 hours after surgery

Secondary Outcomes (2)

• analgesic consumption

  24 hours

• duration of analgesia

  24 hours after block

Study Arms (3)

Control group

NO INTERVENTION

the patients will receive regular analgesics (1 µg /kg fentanyl with induction and 15mg/kg paracetamol before extubation)

TAP group

ACTIVE COMPARATOR

the patients will receive bilateral TAP block using (0.5 ml/ kg bupivacaine 0.25%) in each side + regular analgesics.

Other: regional nerve block

quadratus lumborum group

ACTIVE COMPARATOR

the patients will receive bilateral quadratus lumborum block using (0.5 ml/ kg bupivacaine 0.25%) in each side + regular analgesics.

Other: regional nerve block

Interventions

regional nerve block OTHER

Abdominal field blocks have been used in anesthesia for surgery involving the anterior abdominal wall with ultrasound-guided technique. TAP block is a regional anesthetic technique that blocks neural afferents of the anterolateral abdominal wall. Using anatomical landmark guidance or with the aid of ultrasound (US), local anesthetic is injected into the transversus abdominis fascial plane, where the nerves from T6 to L1 are located. Ultrasound-guided quadratus lumborum (QL) block is considered now as one of the novel truncal abdominal blocks, as it is effective in preventing somatic pain associated with upper and lower abdominal surgeries.

TAP group; quadratus lumborum group

Eligibility Criteria

• Age: 1 Year - 7 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Child (0-17)

You may qualify if:

• ASA I-II physical status patients
• Children scheduled for laparoscopic surgery
• Duration of Laparoscopic procedure not exceeding 90 minutes

You may not qualify if:

• Sensitivities to local anesthetics
• Significant renal, liver, or cardiac disease
• Surgery requiring an open procedure
• Participants refusing regional block
• Those having bleeding disorders, skin lesions or wounds at the site of proposed needle insertion, evidence of peritonitis, septicemia
• Children required emergency procedures.

Sponsors & Collaborators

• Minia University: lead

Study Sites (1)

Minya University

Minya, 61519, Egypt

Location

MeSH Terms

Conditions

Pain, Postoperative

Condition Hierarchy (Ancestors)

Postoperative Complications; Pathologic Processes; Pathological Conditions, Signs and Symptoms; Pain; Neurologic Manifestations; Signs and Symptoms

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: DOUBLE
• Who Masked: PARTICIPANT, OUTCOMES ASSESSOR
• Purpose: TREATMENT
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Professor

Study Record Dates

• First Submitted: August 31, 2020
• First Posted: September 17, 2020
• Study Start: October 1, 2019
• Primary Completion: November 1, 2020
• Study Completion: December 1, 2020
• Last Updated: August 1, 2023

Record last verified: 2023-07

Locations

EG (1)