Multivisceral Resection in Distal Pancreatectomy

NCT04317352 | Completed

• 1 other identifier: UE-CHU 003-2020
• Study Type: observational
• Target: 435
• Locations: 1 country
• Sites: 1

Brief Summary

The objective of the study is to evaluate the characteristics of the patients and the results of morbidity and mortality after distal pancreatectomy isolated or accompanied by multivisceral resection including cholecystectomy.

Conditions

Pancreatic Neoplasms; Surgical Procedure, Unspecified

Keywords

Complications; distal pancreatectomy; Multivisceral; resection

Outcome Measures

Primary Outcomes (2)

• Morbidity

  Any complication in the postoperative period

  90 days

• Mortality

  If the patient dies in the postoperative period

  90 days

Study Arms (1)

Multivisceral resection (MRV)

MVR: Multivisceral resection was considered when the exeresis of an organ other than the pancreatic body-tail and / or spleen was performed.

Procedure: MVR

Interventions

MVR PROCEDURE

Multivisceral resection was considered when the exeresis of an organ other than the pancreatic body-tail and / or spleen was performed.

Multivisceral resection (MRV)

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

Patients undergoing distal pancreatectomy for primary pancreatic tumor at participating centers during the period from January 2009 to December 2018

You may qualify if:

• Any distal pancreatectomy (DP) with multivisceral resection (MVR) defining MVR as any organ different from distal pancreas or spleen

You may not qualify if:

• Distal Pancreatectomy with celiac trunk resection (Appleby procedure) or portal vein resection.

Sponsors & Collaborators

• Universidad de Extremadura: lead

Study Sites (1)

Universidad de Extremadura- Facultad de Medicina

Badajoz, 06080, Spain

Location

Related Publications (7)

• Malinka T, Klein F, Andreou A, Pratschke J, Bahra M. Distal Pancreatectomy Combined with Multivisceral Resection Is Associated with Postoperative Complication Rates and Survival Comparable to Those After Standard Procedures. J Gastrointest Surg. 2018 Sep;22(9):1549-1556. doi: 10.1007/s11605-018-3804-z. Epub 2018 May 10.

  PMID: 29748738 BACKGROUND

• Burdelski CM, Reeh M, Bogoevski D, Gebauer F, Tachezy M, Vashist YK, Cataldegirmen G, Yekebas E, Izbicki JR, Bockhorn M. Multivisceral resections in pancreatic cancer: identification of risk factors. World J Surg. 2011 Dec;35(12):2756-63. doi: 10.1007/s00268-011-1263-8.

  PMID: 21938586 BACKGROUND

• Panzeri F, Marchegiani G, Malleo G, Malpaga A, Maggino L, Marchese T, Salvia R, Bassi C, Butturini G. Distal pancreatectomy associated with multivisceral resection: results from a single centre experience. Langenbecks Arch Surg. 2017 May;402(3):457-464. doi: 10.1007/s00423-016-1514-0. Epub 2016 Oct 27.

  PMID: 27787606 BACKGROUND

• Irani JL, Ashley SW, Brooks DC, Osteen RT, Raut CP, Russell S, Swanson RS, Whang EE, Zinner MJ, Clancy TE. Distal pancreatectomy is not associated with increased perioperative morbidity when performed as part of a multivisceral resection. J Gastrointest Surg. 2008 Dec;12(12):2177-82. doi: 10.1007/s11605-008-0605-9. Epub 2008 Aug 2.

  PMID: 18677539 BACKGROUND

• Song KB, Kwon J, Kim YW, Hwang DW, Lee JH, Hong S, Lee JW, Hwang K, Yoo D, Kim SC. Prognostic value of adjacent organ resection in patients with left-sided pancreatic ductal adenocarcinoma following distal pancreatectomy. J Hepatobiliary Pancreat Sci. 2019 Jun;26(6):227-234. doi: 10.1002/jhbp.627. Epub 2019 May 11.

  PMID: 30980486 BACKGROUND

• Nikfarjam M, Sehmbey M, Kimchi ET, Gusani NJ, Shereef S, Avella DM, Staveley-O'Carroll KF. Additional organ resection combined with pancreaticoduodenectomy does not increase postoperative morbidity and mortality. J Gastrointest Surg. 2009 May;13(5):915-21. doi: 10.1007/s11605-009-0801-2. Epub 2009 Feb 7.

  PMID: 19198960 BACKGROUND

• Ramia JM, Del Rio-Martin JV, Blanco-Fernandez G, Cantalejo-Diaz M, Rotellar-Sastre F, Sabater-Orti L, Carabias-Hernandez A, Manuel-Vazquez A, Hernandez-Rivera PJ, Jaen-Torrejimeno I, Kalviainen-Mejia HK, Esteban-Gordillo S, Munoz-Forner E, De la Plaza R, Longoria-Dubocq T, De Armas-Conde N, Pardo-Sanchez F, Garces-Albir M, Serradilla-Martin M. Distal pancreatectomy with multivisceral resection: A retrospective multicenter study - Case series. Int J Surg. 2020 Oct;82:123-129. doi: 10.1016/j.ijsu.2020.08.024. Epub 2020 Aug 26.

  PMID: 32860956 DERIVED

MeSH Terms

Conditions

Pancreatic Neoplasms

Condition Hierarchy (Ancestors)

Digestive System Neoplasms; Neoplasms by Site; Neoplasms; Endocrine Gland Neoplasms; Digestive System Diseases; Pancreatic Diseases; Endocrine System Diseases

Study Officials

• José Manuel Ramia, MD, PhD

  Hospital Universitario de Guadalajara

  STUDY DIRECTOR

Study Design

• Study Type: observational
• Observational Model: CASE ONLY
• Time Perspective: RETROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Chief of department

Study Record Dates

• First Submitted: March 19, 2020
• First Posted: March 23, 2020
• Study Start: March 1, 2019
• Primary Completion: December 31, 2019
• Study Completion: March 1, 2020
• Last Updated: March 23, 2020

Record last verified: 2020-03

Locations

ES (1)