Upper-body High-intensity Interval Training and Mixed Meal Responses

NCT04277091 | Completed

• 1 other identifier: EP 18/19 087
• Study Type: interventional
• Target: 11
• Locations: 1 country
• Sites: 1

Brief Summary

Cycling and running-based high-intensity interval training are well-established to improve a variety of health outcomes. However, the efficacy of upper-body high-intensity interval training, vital for individuals with lower-body impairments, has yet to be well-characterized. The purpose of this study is to compare the effect of a single bout of upper-body high-intensity interval exercise (HIIE) in comparison to traditional moderate-intensity continuous exercise (MICE) on the blood response (e.g. glucose, insulin, fats) following a meal. This study is recruiting able-bodied adults (aged 18-65 years). Participants will need to attend the laboratory at the University of Bath for two preliminary sessions, and three main study trials.

Conditions

High-Intensity Interval Training

Keywords

postprandial metabolism

Outcome Measures

Primary Outcomes (1)

• Postprandial triglyceride concentrations

  Postprandial triglyceride concentrations in serum samples

  5 hours

Secondary Outcomes (8)

• Postprandial glucose concentrations

  5 hours

• Postprandial insulin concentrations

  5 hours

• Postprandial substrate oxidation

  5 hours

• Rating of Perceived Exertion

  HIIE: End of Warm-Up, 8 min, 12 min, 16 min, 20 min, 24 min. MICE: 0, 20, 40, 60, 80, 100% through exercise session (exact time points dependent on exercise time for each participant)

• Heart Rate

  HIIE: End of Warm-Up, 8 min, 12 min, 16 min, 20 min, 24 min. MICE: 0, 20, 40, 60, 80, 100% through exercise session (exact time points dependent on exercise time for each participant)

Study Arms (3)

Control

NO INTERVENTION

No exercise

High-intensity interval exercise

EXPERIMENTAL

10 x 60 s intervals at 80% peak power output (interspersed with 60 s recovery intervals at 10% peak power output)

Other: High-intensity interval training

Moderate-intensity continous exercise

EXPERIMENTAL

50% peak power output (duration determined to elicit same energy expenditure as high-intensity interval exercise condition)

Other: Moderate-intensity continuos training

Interventions

High-intensity interval training OTHER

Arm-cranking exercise

High-intensity interval exercise

Moderate-intensity continuos training OTHER

Arm-cranking exercise

Moderate-intensity continous exercise

Eligibility Criteria

• Age: 18 Years - 65 Years
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• Non-smoker
• No history of cardiovascular, metabolic, or neuromuscular disease

You may not qualify if:

• Individuals with a nut allergy

Sponsors & Collaborators

• University of Bath: lead

Study Sites (1)

Department for Health

Bath, BA2 7AY, United Kingdom

Location

MeSH Terms

Interventions

High-Intensity Interval Training

Intervention Hierarchy (Ancestors)

Physical Conditioning, Human; Exercise; Motor Activity; Movement; Musculoskeletal Physiological Phenomena; Musculoskeletal and Neural Physiological Phenomena

Study Officials

• James Bilzon

  University of Bath

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: NONE
• Purpose: BASIC SCIENCE
• Intervention Model: CROSSOVER
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Professor

Study Record Dates

• First Submitted: February 10, 2020
• First Posted: February 20, 2020
• Study Start: October 21, 2019
• Primary Completion: January 1, 2021
• Study Completion: January 1, 2021
• Last Updated: July 27, 2022

Record last verified: 2022-07

Locations

GB (1)