NCT02626767

Brief Summary

Low-volume high-intensity interval exercise training may improve aspects of health and fitness in young people, but interventions must be practical and engaging. The investigators examined the effect of a novel school-based low-volume high-intensity interval training programme on health, fitness and physical activity outcomes in adolescent school pupils. 101 English adolescents aged 13-14 years took part in the study. Participants were healthy male and female volunteers, recruited from four schools in Northeast England. Using a non-randomised design, two schools took part in the intervention, and two were assigned to the control. Those in the intervention group completed a 10-week school-based high-intensity interval exercise training programme. The intervention took place three times per week, and comprised of 4-7 repetitions of 45 s maximal effort exercise (boxing, dance, soccer and basketball drills), each interspersed with 90-s rest. Participants were encouraged to work maximally during the 45-s repetitions. Control participants were instructed not to change their lifestyle, dietary or physical activity habits during the intervention period, and maintain their normal school physical education routine. Study outcomes were blood lipid and glucose levels, body composition, cardiorespiratory fitness, carotid intima-media thickness, physical activity levels, serum C-reactive protein levels and blood pressure.

Trial Health

100
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
101

participants targeted

Target at P50-P75 for not_applicable

Timeline
Completed

Started Feb 2011

Shorter than P25 for not_applicable

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

February 1, 2011

Completed
9 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

November 1, 2011

Completed
1 month until next milestone

Study Completion

Last participant's last visit for all outcomes

December 1, 2011

Completed
4 years until next milestone

First Submitted

Initial submission to the registry

December 3, 2015

Completed
7 days until next milestone

First Posted

Study publicly available on registry

December 10, 2015

Completed
Last Updated

December 10, 2015

Status Verified

December 1, 2015

Enrollment Period

9 months

First QC Date

December 3, 2015

Last Update Submit

December 7, 2015

Conditions

Keywords

high-intensity interval trainingadolescentsschool-based exercisecardiometabolic health

Outcome Measures

Primary Outcomes (12)

  • Change from baseline (0 weeks) waist circumference at the post-intervention time point (10 weeks)

    Baseline (0 weeks) and post-intervention (10-weeks)

  • Change from baseline (0 weeks) blood lipids at the post-intervention time point (10 weeks) (assessed via finger prick blood sampling)

    Baseline (0 weeks) and post-intervention (10-weeks)

  • Change from baseline (0 weeks) blood glucose at the post-intervention time point (10 weeks) (assessed via finger prick blood sampling)

    Baseline (0 weeks) and post-intervention (10-weeks)

  • Change from baseline (0 weeks) blood pressure at the post-intervention time point (10 weeks)

    Baseline (0 weeks) and post-intervention (10-weeks)

  • Change from baseline (0 weeks) carotid artery intima-media thickness at the post-intervention time point (10 weeks)

    Baseline (0 weeks) and post-intervention (10-weeks)

  • Change from baseline (0 weeks) body mass index at the post-intervention time point (10 weeks)

    Baseline (0 weeks) and post-intervention (10-weeks)

  • Change from baseline (0 weeks) serum C-reactive protein at the post-intervention time point (10 weeks)

    Baseline (0 weeks) and post-intervention (10-weeks)

  • Change from baseline (0 weeks) 20m shuttle run test performance (indirect measure of cardiorespiratory fitness) at the post-intervention time point (10 weeks)

    Baseline (0 weeks) and post-intervention (10-weeks)

  • Change from baseline (0 weeks) daily physical activity levels (assessed via accelerometry) at the post-intervention time point (10 weeks)

    Baseline (0 weeks) and post-intervention (10-weeks)

  • Change from baseline (0 weeks) body weight at the post-intervention time point (10 weeks)

    Baseline (0 weeks) and post-intervention (10-weeks)

  • Change from baseline (0 weeks) percentage body fat at the post-intervention time point (10 weeks)

    Baseline (0 weeks) and post-intervention (10-weeks)

  • Change from baseline (0 weeks) skeletal muscle mass at the post-intervention time point (10 weeks)

    Baseline (0 weeks) and post-intervention (10-weeks)

Other Outcomes (1)

  • Heart rate during high-intensity interval training exercise sessions

    Up to 10 weeks

Study Arms (2)

Intervention

EXPERIMENTAL

Participants were required to complete a high-intensity interval exercise training intervention, which took place three time per week for 10 weeks. The exercise sessions comprised of 4 to 7 repetitions of 45 s maximal effort exercise, based on boxing, dance, soccer and basketball drills), interspersed with 90-s rest. During each repetitions participants were encouraged to reach \>90% of their individual maximal heart rate. Participants were asked to maintain their dietary habits throughout the intervention period.

Other: Novel high-intensity interval exercise training

Control

NO INTERVENTION

Participants were asked to maintain their usual diet, physical education and physical activity habits during the intervention period and were not aware that an exercise intervention was taking place at other study sites.

Interventions

Please see information already included in the 'intervention' arm description.

Intervention

Eligibility Criteria

Age13 Years - 15 Years
Sexall
Healthy VolunteersYes
Age GroupsChild (0-17)

You may qualify if:

  • Must attend one of the four schools that the study will take place in
  • Must be in the Year 9 English school year (aged 13-15 years)
  • Must provide parental consent and participant assent

You may not qualify if:

  • Symptoms of or known presence of heart disease or major atherosclerotic cardiovascular disease
  • Condition or injury or co-morbidity affecting the ability to undertake exercise
  • Diabetes mellitus
  • Early family history of sudden cardiac death
  • Condition or disorder which is communicable via blood
  • Pregnancy or likelihood of pregnancy

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Related Publications (1)

  • Weston KL, Azevedo LB, Bock S, Weston M, George KP, Batterham AM. Effect of Novel, School-Based High-Intensity Interval Training (HIT) on Cardiometabolic Health in Adolescents: Project FFAB (Fun Fast Activity Blasts) - An Exploratory Controlled Before-And-After Trial. PLoS One. 2016 Aug 3;11(8):e0159116. doi: 10.1371/journal.pone.0159116. eCollection 2016.

Study Officials

  • Kathryn L Weston, PhD

    Teesside University, Middlesbrough,UK

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
NON RANDOMIZED
Masking
NONE
Purpose
PREVENTION
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Senior Lecturer in Applied Biosciences for Health

Study Record Dates

First Submitted

December 3, 2015

First Posted

December 10, 2015

Study Start

February 1, 2011

Primary Completion

November 1, 2011

Study Completion

December 1, 2011

Last Updated

December 10, 2015

Record last verified: 2015-12

Data Sharing

IPD Sharing
Will not share

Only group level data will be published from this study.