NCT04183400

Brief Summary

The SAFE study examines the effects of brief mindfulness-based cognitive-behavioral intervention aimed at improving risk-related attention skills (risk detection, problem solving, assertiveness, and help seeking) in order to reduce substance use and victimization among young people (ages 18-21) experiencing homelessness.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
244

participants targeted

Target at P75+ for not_applicable

Timeline
Completed

Started Sep 2015

Longer than P75 for not_applicable

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

Study Start

First participant enrolled

September 1, 2015

Completed
4.2 years until next milestone

First Submitted

Initial submission to the registry

November 15, 2019

Completed
18 days until next milestone

First Posted

Study publicly available on registry

December 3, 2019

Completed
6 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

June 1, 2020

Completed
3 months until next milestone

Study Completion

Last participant's last visit for all outcomes

September 1, 2020

Completed
Last Updated

September 28, 2020

Status Verified

September 1, 2020

Enrollment Period

4.8 years

First QC Date

November 15, 2019

Last Update Submit

September 25, 2020

Conditions

Keywords

substance usevictimizationhomeless youthyouth experiencing homelessness

Outcome Measures

Primary Outcomes (6)

  • Substance use

    The Substance use domain of the Addiction Severity Index, 5th edition will be used to assess the frequency, type and amount of substance use in the past 30 days. This domain will be adapted to add smoking tobacco to the list of substances.

    Follow up at 6-weeks post baseline interview

  • Substance use

    The Substance use domain of the Addiction Severity Index, 5th edition will be used to assess the frequency, type and amount of substance use in the past 30 days. This domain will be adapted to add smoking tobacco to the list of substances.

    Follow up at 3-months post baseline interview

  • Substance use

    The Substance use domain of the Addiction Severity Index, 5th edition will be used to assess the frequency, type and amount of substance use in the past 30 days. This domain will be adapted to add smoking tobacco to the list of substances.

    Follow up at 6-months post baseline interview

  • Victimization

    The Juvenile Victimization Questionnaire (JVQ) will be used to asses exposure to a range of types of victimization.

    Follow up at 6-weeks post baseline interview

  • Victimization

    The Juvenile Victimization Questionnaire (JVQ) will be used to asses exposure to a range of types of victimization.

    Follow up at 3-months post baseline interview

  • Victimization

    The Juvenile Victimization Questionnaire (JVQ) will be used to asses exposure to a range of types of victimization.

    Follow up at 6-months post baseline interview

Secondary Outcomes (6)

  • Substance use symptoms

    Follow up at 6-weeks, 3-months, and 6-months post baseline interview, controlling for baseline

  • Substance use disorder diagnostic criteria

    Follow up at 6-weeks, 3-months, and 6-months post baseline interview, controlling for baseline

  • Risk detection

    Follow up at 1-week, 6-weeks, and 3-months post baseline interview, controlling for baseline

  • Help seeking intentions

    Follow up at 1-week, 6-weeks, and 3-months post baseline interview, controlling for baseline

  • Help seeking behaviors

    Follow up at 1-week, 6-weeks, and 3-months post baseline interview, controlling for baseline

  • +1 more secondary outcomes

Study Arms (2)

Safety Awareness For Empowerment (SAFE)

EXPERIMENTAL

Brief mindfulness-based cognitive-behavioral skill-building intervention

Behavioral: Safety Awareness For Empowerment (SAFE)

Usual case management only

NO INTERVENTION

Control condition receives only services as usual

Interventions

SAFE is a mindfulness-based cognitive-behavioral intervention that aims to build risk-related attention skills.

Safety Awareness For Empowerment (SAFE)

Eligibility Criteria

Age18 Years - 21 Years
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64)

You may qualify if:

  • Reside at the partnering community based youth shelter

You may not qualify if:

  • As measured by the KSADS (a semi-structured diagnostic interview administered by trained interviewers at baseline):
  • presence of psychotic symptoms;
  • presence of a life-threatening medical/chronic neurological illness that would prevent participation in a 4-day intervention and/or assessments;
  • suicide attempt in last 6 months without current enrollment in therapy or related services to address;
  • chronic self-injurious behavior/cutting without current enrollment in therapy or related services to address
  • hospitalization or residential treatment for psychiatric reasons in last 6 months without current enrollment in therapy or related services to address.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Urban Peak Shelter and University of Denver

Denver, Colorado, 80223, United States

Location

MeSH Terms

Conditions

Substance-Related Disorders

Condition Hierarchy (Ancestors)

Chemically-Induced DisordersMental Disorders

Study Officials

  • Kimberly Bender, PhD

    University of Denver

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
NONE
Purpose
PREVENTION
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Professor

Study Record Dates

First Submitted

November 15, 2019

First Posted

December 3, 2019

Study Start

September 1, 2015

Primary Completion

June 1, 2020

Study Completion

September 1, 2020

Last Updated

September 28, 2020

Record last verified: 2020-09

Data Sharing

IPD Sharing
Will not share

Locations