Study Stopped
The study was prematurely discontinued due to a lack of efficacy in sub-study 1
A Study Evaluating the Efficacy and Safety of Oral Etrasimod in the Treatment of Adult Participants With Moderately to Severely Active Crohn's Disease
CULTIVATE
A Multicenter, Randomized, Double-Blind, Parallel-Group Study to Assess the Efficacy and Safety of Oral Etrasimod as Induction and Maintenance Therapy for Moderately to Severely Active Crohn's Disease
2 other identifiers
interventional
375
39 countries
497
Brief Summary
This is a Phase 2/3 study that comprises 5 substudies designed to evaluate the efficacy, safety, and tolerability of oral etrasimod as therapy in adult participants with moderately to severely active Crohn's disease (CD) who are refractory or intolerant to at least 1 of the current therapies for CD (ie, corticosteroids, immunosuppressants, or biologics). The overall duration of this study is up to 282 weeks, inclusive of the Screening Period, Treatment Period of up to 274 weeks (Induction, Extension or Maintenance, and Long-term Extension Periods), and the 4-Week Follow-Up Period for safety assessment.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P50-P75 for phase_3
Started Jan 2020
Longer than P75 for phase_3
497 active sites
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
Click on a node to explore related trials.
Study Timeline
Key milestones and dates
First Submitted
Initial submission to the registry
November 20, 2019
CompletedFirst Posted
Study publicly available on registry
November 21, 2019
CompletedStudy Start
First participant enrolled
January 6, 2020
CompletedPrimary Completion
Last participant's last visit for primary outcome
April 23, 2025
CompletedStudy Completion
Last participant's last visit for all outcomes
June 9, 2025
CompletedJuly 16, 2025
July 1, 2025
5.3 years
November 20, 2019
July 11, 2025
Conditions
Keywords
Outcome Measures
Primary Outcomes (6)
Proportion of Participants with Endoscopic Response [Substudy A]
Weeks 14 and 52
Proportion of Participants With Endoscopic Response [Substudy 1]
Week 14
Proportion of Participants With Endoscopic Response [Substudy 2]
Week 14
Proportion of Participants With Clinical Remission Crohn's Disease Activity Index (CDAI) [Substudy 2]
Week 14
Proportion of Participants With Clinical Remission CDAI [Substudy 3]
Week 52
Proportion of Participants With Endoscopic Response [Substudy 3]
Week 52
Secondary Outcomes (19)
Proportion of Participants With Clinical Remission CDAI [Substudy A]
Up to Week 66
Change From Baseline in Simple Endoscopic Score in Crohn's Disease (SES-CD) Score [Substudy A]
Baseline to Week 66
Change From Baseline in CDAI Score [Substudy A]
Baseline to Week 66
Proportion of Participants With Clinical Remission CDAI [Substudy 1]
Week 14
Proportion of Participants with Clinical Remission Patient Reported Outcome 2 (PRO2) [Substudy 1]
Week 14
- +14 more secondary outcomes
Study Arms (3)
Etrasimod Dose A
EXPERIMENTALEtrasimod Dose B
EXPERIMENTALPlacebo
PLACEBO COMPARATORInterventions
Eligibility Criteria
You may qualify if:
- Men or women 18 to 80 years of age,
- Ability to provide written informed consent or assent and to be compliant with the schedule of protocol assessments
- Diagnosed with Crohn's disease (CD) ≥ 3 months
- Have moderately to severely active CD at Screening
- Demonstrated inadequate response (ie, primary non-response), loss of response to, or intolerance to ≥ 1 of the following therapies for the treatment of CD:
- Oral corticosteroids (eg, prednisone or its equivalent, budesonide)
- Immunosuppressants (eg, azathioprine \[AZA\], 6 mercaptopurine \[6-MP\], or methotrexate \[MTX\])
- Tumor necrosis factor alpha (TNFα) antagonists (eg, infliximab, adalimumab, certolizumab pegol, or biosimilars)
- Integrin receptor antagonist (eg, vedolizumab)
- Interleukin -12/-23 antagonist (eg, ustekinumab)
- Females of childbearing potential must be nonpregnant
- Females of childbearing potential and males must use contraception
You may not qualify if:
- History of inadequate response (ie, primary non-response) to agents from ≥ 2 classes of biologics marketed for the treatment of CD (ie, TNFα antagonists, interleukin 12/ 23 antagonist, and integrin receptor antagonist).
- Have ulcerative colitis, indeterminate colitis, microscopic colitis, ischemic colitis, radiation colitis, diverticular disease associated colitis, toxic megacolon, or active infectious colitis or test positive for Clostridioides difficile toxin at Screening.
- Have functional or post-operative short-bowel syndrome or any associated complications that may require surgery or interfere with efficacy assessments
- Had surgical treatment for intra abdominal abscesses ≤ 8 weeks prior to randomization or surgical treatment for perianal abscesses ≤ 4 weeks prior to randomization.
- Had intestinal resection ≤ 24 weeks prior to randomization or other intra abdominal surgeries ≤ 12 weeks prior to randomization.
- Have an ileostomy or a colostomy.
- \- Participants who entered the Extended Induction Period of Substudy 1 and Substudy 2 must have completed the Extended Induction -Week 6 Visit
- \- Participant must have completed the Week 52 Visit of Substudy 3 or the Week 66 Visit of Substudy A
Contact the study team to confirm eligibility.
Sponsors & Collaborators
- Pfizerlead
- Arena is a wholly owned subsidiary of Pfizercollaborator
Study Sites (519)
Center for Digestive Health (Endoscopy Location)
Dothan, Alabama, 36301, United States
Digestive Health Specialists
Dothan, Alabama, 36301, United States
Dothan Eyecare-Dr. Brent McKinley (OCT Location)
Dothan, Alabama, 36301, United States
Pulmonary Associates (PFT Location)
Dothan, Alabama, 36301, United States
Flowers Hospital (Imaging Location)
Dothan, Alabama, 36305, United States
Digestive Health Specialists (Satellite Clinic Location)
Mobile, Alabama, 36608, United States
Premier Medical Group East (Opthalmology & Optometry Facility)
Mobile, Alabama, 36608, United States
Pulmonary Associates (Chest X-Ray & PFT Facility)
Mobile, Alabama, 36608, United States
Surgicare of Mobile (Endoscopy & Biopsy Facility)
Mobile, Alabama, 36608, United States
Arizona Retina Institute/ Phoenix Retina Associates(OCT)
Peoria, Arizona, 85381, United States
SimonMed Imaging (Imaging)
Peoria, Arizona, 85381, United States
Sun City Endoscopy Center (Endoscopy)
Sun City, Arizona, 85351, United States
Om Research LLC
Apple Valley, California, 92307, United States
Victor Valley Advanced Imaging
Apple Valley, California, 92307, United States
Koman Family Outpatient Pavilion (ENDO)
La Jolla, California, 92037, United States
Perlman Medical Offices
La Jolla, California, 92037, United States
UCSD Clinical and Translational Research Institute
La Jolla, California, 92037, United States
UCSD Health System (Endo/PFT/DLCO)
La Jolla, California, 92037, United States
UCSD lnvestigational Drug Service Pharmacy
La Jolla, California, 92037, United States
Shiley Eye Institute (OCT)
La Jolla, California, 92093, United States
A V Pediatrics, Allergy and Family Medicine - PFT
Lancaster, California, 93534, United States
Advanced Endoscopy and Pain Center - Colonoscopy
Lancaster, California, 93534, United States
Advanced Imaging Center - Chest X-Ray
Lancaster, California, 93534, United States
Antelope Valley Eye Care - Ophthalmologist
Lancaster, California, 93534, United States
AV Pediatrics Allergy and Family Medicine
Lancaster, California, 93534, United States
Jatinder S. Pruthi, MD FACG CPI
Lancaster, California, 93534, United States
OM Research LLC
Lancaster, California, 93534, United States
United Medical Doctors
Murrieta, California, 92563, United States
Retina Consultants of Southern California
Victorville, California, 92392, United States
Physicians Surgery Center
Victorville, California, 92395, United States
Front Range Endoscopy Center
Colorado Springs, Colorado, 80903, United States
Peak Gastroenterology Associates
Colorado Springs, Colorado, 80907, United States
Colorado Springs Pulmonary Consultants, PC
Colorado Springs, Colorado, 80909, United States
The Wright Eye Center (OCT Facility)
Colorado Springs, Colorado, 80909, United States
Colorado Springs Imaging (Ultrasound and MRE Location)
Colorado Springs, Colorado, 80919, United States
Xera Med Research
Boca Raton, Florida, 33487, United States
RecioMed Clinical Research Network, Inc
Boynton Beach, Florida, 33472, United States
Florida Advanced Gastroenterology Center - Rahman Nakshabendi MD and Imad Nakshabendi, MD
Brandon, Florida, 33511, United States
Bay Area Chest Physicians, P.A. (Pulmonary Function Test)
Clearwater, Florida, 33756, United States
West Coast Endoscopy Center (Endoscopy Procedures)
Clearwater, Florida, 33756, United States
Northwood Vision (Optical Coherence Tomography)
Clearwater, Florida, 33761, United States
Safety Harbor Surgery (Endoscopy Procedures)
Clearwater, Florida, 33761, United States
Gastro Florida (Regulatory Administrative Duties)
Clearwater, Florida, 33762, United States
Beraja Medical Institute (OCT)
Coral Gables, Florida, 33134, United States
Advanced Eye Center
Hialeah, Florida, 33012, United States
UF Health Imaging Center-Emerson (chest x-rays)
Jacksonville, Florida, 32207, United States
UF Health Laboratory Emerson (blood draws)
Jacksonville, Florida, 32207, United States
UF Health Jacksonville Respiratory Therapy (PFT and DLCO)
Jacksonville, Florida, 32209, United States
UF Health Jacksonville-Faculty Clinic (ileocolonoscopy and biopsy)
Jacksonville, Florida, 32209, United States
UF Health Opthalmology - Jacksonville (Ophthalmology with OCT)
Jacksonville, Florida, 32209, United States
UF Health Radiology-Jacksonville (chest x-rays)
Jacksonville, Florida, 32209, United States
Cisca Pulmonary & Critical Care (PFT Facility)
Jacksonville, Florida, 32216, United States
Nicolitz Eye Consultants (OCT Facility)
Jacksonville, Florida, 32216, United States
Borland-Groover Clinic (Endoscopy Facility)
Jacksonville, Florida, 32256, United States
Encore Borland-Groover Clinical Research
Jacksonville, Florida, 32256, United States
Jupiter Outpatient Surgery Center
Jupiter, Florida, 33458, United States
IHS Health, LLC
Kissimmee, Florida, 34741, United States
Lee Shettle Eye & Hearing (Ophthalmoscopy Only)
Largo, Florida, 33773, United States
Infinite Clinical Research
Miami, Florida, 33133, United States
Pulmonology Physicians of South Florida
Miami, Florida, 33133, United States
Reina Eye Care P.A.
Miami, Florida, 33133, United States
The Endoscopy Center (Endoscopy Procedure)
Miami, Florida, 33134, United States
La Salud Research Clinic Inc.
Miami, Florida, 33155, United States
Research Associates of South Florida
Miami, Florida, 33156, United States
South Florida Center for Endoscopy and Digestive Disease, LLC
Miami, Florida, 33156, United States
Juan Barrio, MD (PFT when needed)
Miami, Florida, 33173, United States
Anchor Medical Research, Llc
Miami, Florida, 33176, United States
Gastroenterology Group of Naples
Naples, Florida, 34102, United States
Gulfshore Endoscopy Center
Naples, Florida, 34102, United States
Retina Consultants of Southwest Florida OCT only
Naples, Florida, 34103, United States
Lisette Delgado Sanchez, MD PFT only
Naples, Florida, 34109, United States
Pediatric & Adult Research Center
Orlando, Florida, 32825, United States
IMIC Inc.
Palmetto Bay, Florida, 33157, United States
IMIC Inc
Palmetto Bay, Florida, 33157, United States
Advanced Medical Research Center
Port Orange, Florida, 32127, United States
Bardmoor GastroEnterology
Seminole, Florida, 33777, United States
Larkin Community Hospital (Endoscopy Procedure)
South Miami, Florida, 33143, United States
St. Petersburg Endoscopy Center (Endoscopy Procedures)
St. Petersburg, Florida, 33705, United States
Pasadena Center for Asthma and Lung Disorders (PFT and DLCO Only)
St. Petersburg, Florida, 33707, United States
Bay Area Endoscopy and Surgery Center (Endoscopy only)
St. Petersburg, Florida, 33709, United States
Theia Clinical Research, LLC
St. Petersburg, Florida, 33709, United States
Advanced Research Institute Inc.(IP and PFT)
St. Petersburg, Florida, 33710, United States
Absolute Surgical Specialist - Craig Amshel, MD
Sun City Center, Florida, 33573, United States
Lab - Processing/ Storage
Tampa, Florida, 33606, United States
USF Health South Tampa Center for Advanced Healthcare
Tampa, Florida, 33606, United States
GCP Clinical Research,LLC
Tampa, Florida, 33609, United States
LoCicero Medical Group
Tampa, Florida, 33609, United States
Newsome Eye Specialist (OCT Procedures Only)
Tampa, Florida, 33609, United States
South Tampa Surgery Center
Tampa, Florida, 33609, United States
USF Health Morsani Center For Advanced Healthcare
Tampa, Florida, 33612, United States
Digestive Healthcare of Georgia
Atlanta, Georgia, 30309, United States
Peachtree Allergy and Asthma Clinic - Chest X-rays and PFTs
Atlanta, Georgia, 30309, United States
Ross Eyecare - Opthalmoscopy and OCT
Atlanta, Georgia, 30324, United States
Atlanta Gastroenterology Associates (endoscopy only)
Atlanta, Georgia, 30342, United States
Atlanta Gastroenterology Associates(IP only)
Atlanta, Georgia, 30342, United States
Atlanta Gastroenterology Associates
Atlanta, Georgia, 30342, United States
GI Alliance
Arlington Heights, Illinois, 60005, United States
Northwest Endoscopy Center (Endoscopy)
Arlington Heights, Illinois, 60005, United States
GI Alliance (PFT)
Gurnee, Illinois, 60031, United States
Illinois Gastroenterology Group-Gurnee (Patients Seen; IP Delivered)
Gurnee, Illinois, 60031, United States
Medical Eye Services LTD (Ophthalmoscopy with OCT)
Gurnee, Illinois, 60031, United States
North Shore Endoscopy Center (Endoscopy)
Lake Bluff, Illinois, 60044, United States
Libertyville Imaging Center (Diagnostic Imaging)
Libertyville, Illinois, 60048, United States
3T Imaging of Morton Grove (Diagnostic Imaging)
Morton Grove, Illinois, 60053, United States
Charter Radiology
Columbia, Maryland, 21044, United States
Cascades Endoscopy Center
Columbia, Maryland, 21045, United States
Gastro Center of Maryland, LLC
Columbia, Maryland, 21045, United States
Kaylani Eye Care ( Optical Coherence Tomography and Opthalmoscopy only)
Hanover, Maryland, 21076, United States
Lung Center (Pulmonary Function Test only)
Laurel, Maryland, 20707, United States
A Terrell Williams, MD, PLLC (OCT)
Jackson, Mississippi, 39216, United States
Jackson Pulmonary Associates (PFT)
Jackson, Mississippi, 39216, United States
Southern Therapy and Advanced Research, LLC
Jackson, Mississippi, 39216, United States
St. Dominic Ambulatory Surgery Center (colonoscopy, Endoscopy)
Jackson, Mississippi, 39216, United States
Barnes-Jewish West County Hospital (Additional Endoscopy Location)
Creve Coeur, Missouri, 63141, United States
Washington University School of Medicine
St Louis, Missouri, 63108, United States
Barnes-Jewish Hospital
St Louis, Missouri, 63110, United States
Washington University School of Medicine
St Louis, Missouri, 63110, United States
Allied Health Clinical Research Organization, LLC
Freehold, New Jersey, 07728, United States
Freehold Endoscopy Associates, LLC d/b/a Endoscopy Center of Monmouth County
Freehold, New Jersey, 07728, United States
Freehold Ophthalmology
Freehold, New Jersey, 07728, United States
Monmouth Ocean Pulmonary Medicine
Freehold, New Jersey, 07728, United States
Princeton Radiology
Freehold, New Jersey, 07728, United States
NYU Langone Eye Center (Ophthalmology)
New York, New York, 10016, United States
NYU Langone Health - Ambulatory Care Center
New York, New York, 10016, United States
NYU Langone Health, Investigational Pharmacy, Perlmutter Cancer Center
New York, New York, 10016, United States
NYU Langone Health
New York, New York, 10016, United States
NYU Langone Inflammatory Bowel Disease Center
New York, New York, 10016, United States
NYU Pulmonary and Critical Care Associates (Pulmonary)
New York, New York, 10016, United States
Queen City Gastroenterology and Hepatology (Endoscopy)
Charlotte, North Carolina, 28204, United States
Greenman Eye Associates (OCT)
Charlotte, North Carolina, 28211, United States
Carolinas Research Center
Charlotte, North Carolina, 28215, United States
Cornerstone Medical (Imaging & PFT)
Charlotte, North Carolina, 28273, United States
Geauga Sleep Center(PFT only)
Chardon, Ohio, 44024, United States
UC Health Hoxworth (OCT only)
Cincinnati, Ohio, 45219, United States
UC Health Physicians Office
Cincinnati, Ohio, 45219, United States
University of Cincinnati Medical Center (PFT and Endoscopy location)
Cincinnati, Ohio, 45219, United States
UC Health (Pulmonary Function Testing)
Cincinnati, Ohio, 45229, United States
Great Lakes Gastroenterology Research, LLC
Mentor, Ohio, 44060, United States
Ophthalmic Physicians Incorporated (OCT Only)
Mentor, Ohio, 44060, United States
The Endoscopy Center of Lake County
Mentor, Ohio, 44060, United States
Vitreo Retinal Consultants(OCT only)
Mentor, Ohio, 44060, United States
Lake Pulmonary Associates (PFT only)
Willoughby, Ohio, 44094, United States
Retina Specialists of Ohio(OCT only)
Willoughby Hills, Ohio, 44094, United States
Norman Endoscopy Center
Norman, Oklahoma, 73071, United States
Physicians and Surgeons X-Ray
Norman, Oklahoma, 73071, United States
Hightower Clinical
Oklahoma City, Oklahoma, 73102, United States
Saint Anthony Endoscopy Center
Oklahoma City, Oklahoma, 73102, United States
SSM Health, Saint Anthony Hospital
Oklahoma City, Oklahoma, 73102, United States
Central Sooner Research
Oklahoma City, Oklahoma, 73118, United States
Johnston Opthalmology
Oklahoma City, Oklahoma, 73120, United States
Penn State Milton S. Hershey Medical Center
Hershey, Pennsylvania, 17033, United States
Central Texas Clinical Research
Austin, Texas, 78705, United States
Houston Pulmonary Sleep and Allergy Associates (PFT)
Cypress, Texas, 77429, United States
Houston Eye Associates (For Eye Examination)
Houston, Texas, 77024, United States
Alkek Eye Center Jamail Specialty Care Center (OCT)
Houston, Texas, 77030, United States
Baylor College of Medicine - Baylor St. Luke's Medical Center
Houston, Texas, 77030, United States
Baylor St. Luke's Medical Center - McNair Campus (pharmacy)
Houston, Texas, 77030, United States
Baylor St. Luke's Medical Center - McNair Campus
Houston, Texas, 77030, United States
Baylor St. Luke's Medical Center Endoscopy - McNair Campus
Houston, Texas, 77030, United States
Baylor St. Luke's Medical Center
Houston, Texas, 77030, United States
Mann Eye Institute
Houston, Texas, 77030, United States
Memorial Hermann Hospital- TMC Investigational Drugs Services Pharmacy (Drug Storage)
Houston, Texas, 77030, United States
The University of Texas Health Science Center at Houston
Houston, Texas, 77030, United States
Bay Area Endoscopy Center, LLC
Houston, Texas, 77034, United States
Pearland Surgery Center
Houston, Texas, 77047, United States
Memorial Endoscopy Center (For Colonoscopy)
Houston, Texas, 77055, United States
Eye Specialists of Texas
Houston, Texas, 77065, United States
Northside Gastroenterology Associates PA
Houston, Texas, 77065, United States
Memorial Pulmonology(For PFT)
Houston, Texas, 77079, United States
Digestive Health Associates
Houston, Texas, 77204, United States
Memorial Hermann Memorial City Digestive Health Center (For Colonoscopy)
Houston, Texas, 77204, United States
LinQ Research, LLC
Pearland, Texas, 77584, United States
Christus Trinity Mother Frances Endoscopy Center (endoscopies only)
Tyler, Texas, 75701, United States
Heaton Eye Associates (OCT only)
Tyler, Texas, 75701, United States
Tyler Research Institute, LLC
Tyler, Texas, 75701, United States
UT Health East Texas Physicians (pulmonary functions only)
Tyler, Texas, 75701, United States
Citizens Healthplex (for PFT only)
Victoria, Texas, 77904, United States
Surgery Center (For endoscopy only)
Victoria, Texas, 77904, United States
Victoria Eye Center (For OCT only)
Victoria, Texas, 77904, United States
Victoria Gastroenterology
Victoria, Texas, 77904, United States
GI Alliance Webster
Webster, Texas, 77598, United States
Harman Eye Center (OCT only)
Forest, Virginia, 24551, United States
Lynchburg Pulmonary Associates, Inc. (PFT only)
Lynchburg, Virginia, 24501, United States
Blue Ridge Medical Research
Lynchburg, Virginia, 24502, United States
Swedish Endoscopy Center - Issaquah
Issaquah, Washington, 98029, United States
Pacific Northwest Retina
Seattle, Washington, 98104, United States
Richard Bensinger, MD
Seattle, Washington, 98104, United States
Swedish Gastroenterology
Seattle, Washington, 98104, United States
First Hill Endoscopy Center
Seattle, Washington, 98122, United States
Pulmonary Function Lab
Seattle, Washington, 98122, United States
Swedish Medical Center
Seattle, Washington, 98122, United States
Froedtert Memorial Lutheran Hospital
Milwaukee, Wisconsin, 53226, United States
Instituto Medico Elsa Perez(I.M.E.P)
Ciudadela, Prov. de Buenos Aires, 1702, Argentina
Instituto Medico Elsa Perez (I.M.E.P.) (Local Lab)
Ciudadela, Prov. de Buenos Aires, B1702GIK, Argentina
Instituto Medico Elsa Perez (I.M.E.P.) (Pharmacy)
Ciudadela, Prov. de Buenos Aires, B1702GIK, Argentina
Estudio de La Vision (OCT, Ophthalmoscopy)
Hurlingham, Prov. de Buenos Aires, B1686NCI, Argentina
Gastroenterologia Rosario (Endoscopy)
Rosario, Santa Fe Province, S2000AUC, Argentina
Microcirugia Ocular SA (OCT, Ophthalmoscopy)
Rosario, Santa Fe Province, S2000CTC, Argentina
Instituto Medico de la Fundacion Estudios Clinicos
Rosario, Santa Fe Province, S2000DEJ, Argentina
Consultorios extemos de Sanatorio Parque (PFT with DLCO, Pulmonar Functional Test with DLCO)
Rosario, Santa Fe Province, S2000KZD, Argentina
Centro de Investigaciones Medicas Tucuman
San Miguel de Tucumán, Tucumán Province, T4000AXL, Argentina
Macquarie Respiratory Services
Macquarie University, New South Wales, 2109, Australia
Macquarie University Hospital Clinical Trials
Macquarie University, New South Wales, 2109, Australia
Macquarie University Hospital Pharmacy
Macquarie University, New South Wales, 2109, Australia
Macquarie University Hospital
Macquarie University, New South Wales, 2109, Australia
MQ Health Ophthalmology
Macquarie University, New South Wales, 2109, Australia
Royal Brisbane & Women's Hospital
Brisbane, Queensland, 4029, Australia
Coral Sea Clinical Research Institute
North Mackay, Queensland, 4740, Australia
MCES Practice Pty Ltd operating as Comprehensive Eye Surgeons
Bellfield, Victoria, 3081, Australia
The Northern Hospital
Epping, Victoria, 3076, Australia
Austin Hospital
Heidelberg, Victoria, 3084, Australia
Footscray Hospital
Melbourne, Victoria, 3011, Australia
Vision Eye Institute
Melbourne, Victoria, 3011, Australia
The Royal Melbourne Hospital
Parkville, Victoria, 3050, Australia
Heidelberg Eye Clinic
Rosanna, Victoria, 3084, Australia
Fiona Stanley Hospital
Murdoch, Western Australia, 6150, Australia
Lions Eye Institute Limited
Nedlands, Western Australia, 6009, Australia
The trustee for The RTS Unit Trust trading as Respiratory Testing Services
O'Connor, Western Australia, 6163, Australia
LKH Universitats-Klinikum Graz
Graz, 8036, Austria
Medical University Innsbruck, Internal Medicine Ⅰ
Innsbruck, A-6020, Austria
AKH Wien- Universitatsklinik fiir Innere Medizin III
Vienna, 1090, Austria
AKH Wien- Universitatsklinik fur Innere Medizin III
Vienna, 1090, Austria
Univ.-Professor Dr. Mehrdad Baghestanian
Vienna, 1090, Austria
Institution "Gomel Regional Clinical Hospital"
Homyel, 246029, Belarus
Health care Institution "10th City Clinical Hospital"
Minsk, 220096, Belarus
Health Care Institution "Mogilev Hospital #1"
Mogilev, 212018, Belarus
Health Care Institution "Vitebsk Regional Clinical Hospital"
Vitebsk, 210037, Belarus
Healthcare Institution "Vitebsk Regional Clinical Specialized Center"
Vitebsk, 210604, Belarus
AZ Maria-Middelares
Ghent, 9000, Belgium
Universitair Ziekenhuis Gent
Ghent, 9000, Belgium
Universitaire Ziekenhuizen Leuven
Leuven, 3000, Belgium
Campus Brugsesteenweg
Roeselare, 8800, Belgium
Campus Rumbeke
Roeselare, 8800, Belgium
Campus Rembert Torhout
Torhout, 8820, Belgium
Centre Hospitalier Universitaire UCL Namur - Site Godinne
Yvoir, 5530, Belgium
"DCC Alexandrovska", EOOD
Sofia, 1431, Bulgaria
UMHAT "Tsaritsa Yoanna-ISUL" EAD
Sofia, 1527, Bulgaria
,,University multiprofile hospital for active treatment and emergency medicine N.I. Pirogov" EAD
Sofia, 1606, Bulgaria
McGill University Health Centre - Montreal General Hospital (Electrocardiogram Clinic)
Montreal, Quebec, H3G 1A4, Canada
McGill University Health Centre - Montreal General Hospital (Endoscopy Clinic)
Montreal, Quebec, H3G 1A4, Canada
McGill University Health Centre - Montreal General Hospital (Pharmacy)
Montreal, Quebec, H3G 1A4, Canada
McGill University Health Centre - Montreal General Hospital (Radiology)
Montreal, Quebec, H3G 1A4, Canada
McGill University Health Centre - Montreal General Hospital (Research Site)
Montreal, Quebec, H3G 1A4, Canada
Centre for Innovative Medicine - Research Institute of the McGill University Health Centre(Pulmonary
Montreal, Quebec, H4A 3J1, Canada
Eye Health MD (Ophthalmology)
Montreal, Quebec, H4P 2S4, Canada
Centro de Investigaciones Clinicas de la Universidad Catolica
Santiago, RM, 8330034, Chile
Clinica Universidad de los Andes
Santiago, Santiago Metropolitan, 7620157, Chile
CeCim Biocinetic
Santiago, Santiago Metropolitan, 8330336, Chile
Clinica de la Costa Ltda.
Barranquilla, Atlántico, 080020, Colombia
Clinica de la Mujer S.A.S
Bogotá, Bogota D.C., 110221, Colombia
IPS Fundacion Cardiomet CEQUIN
Armenia, Quindío Department, 630004, Colombia
Centro de lnvestigaciones Clinicas S.A.S
Cali, Valle del Cauca Department, 760035, Colombia
Clinical Hospital Centre Osijek
Osijek, 31000, Croatia
University Hospital Center Zagreb
Zagreb, 10000, Croatia
MUDr. Jaroslava Skalova
Horažďovice, 341 01, Czechia
Hepato-Gastroenterologie HK, s.r.o.
Hradec Králové, 500 12, Czechia
VISUS, spol s.r.o.
Hradec Králové, 500 12, Czechia
GASTRO JeKa, s.r.o.
Klatovy, 339 01, Czechia
Klatovska nemocnice a.s.
Klatovy, 339 01, Czechia
MUDr. Pavlina Kazinotova s.r.o.
Olomouc, 779 00, Czechia
Ocni ordinace Olomouc
Olomouc, 779 00, Czechia
PreventaMed s.r.o.
Olomouc, 779 00, Czechia
Aalborg University Hospital, Department of Medical Gastroenterology, Medicinerhuset
Aalborg, 9000, Denmark
Hvidovre University Hospital
Hvidovre, 2650, Denmark
Alexandria Clinical Research Center , Faculty of Medicine , Alexandria University
Alexandria, 21131, Egypt
Ain Shams University Hospital
Cairo, 11556, Egypt
Air Force Specialized Hospital(AFSH)
Cairo, Egypt
Cairo University , Kasr Al Aini Hospital
Cairo, Egypt
National Hepatology and Tropical Medicine Research Institute
Cairo, Egypt
Egyptian Liver Research Institute and Hospital ( ELRIAH)
Dakahlia, Egypt
Theodor Bilharz Research Institute Research Ethics Committee
Giza, Egypt
National Liver Institute
Menofeya, 32511, Egypt
CHU Amiens Picardie
Amiens, 80054, France
CHU de Clermont Ferrand - Hopital Estaing
Clermont-Ferrand, 63000, France
CHU Gabriel Montpied
Clermont-Ferrand, 63000, France
CHU Grenoble Alpes - Hopital Michallon
Grenoble, 38043, France
Endoscopy: CHU Grenoble Alpes- Hopital Michallon
Grenoble, 38043, France
CHD Vendee, Unite de Recherche Clinique
La Roche-sur-Yon, 85925, France
CHU de Lille - Hopital Claude Huriez
Lille, 59037, France
Optical Coherence Tomography and Ophthalmology CHU de Lille Hopital Roger Salengro
Lille, 59037, France
Pulmonary Function Test CHU Lille, Institut Coeur Poumon
Lille, 59037, France
CHU Saint-Eloi
Montpellier, 34295, France
Hopital Saint-Eloi - Pole Digestif - Hgea Recherche Clinique - Rdc
Montpellier, 34295, France
CHU de Nice, Hopital 1'Archet 2
Nice, 06202, France
Hopital Robert Debre
Reims, 51092, France
Hopital Maison Blanche, CHU DE REIMS
Reims, 51100, France
Hopital Robert Debre CHU DE REIMS
Reims, 51100, France
CHU Saint Etienne - Hopital Nord
Saint-Etienne, 42055, France
Optical Coherence Tomography and Ophthalmology
Saint-Priest-en-Jarez, 42270, France
Pulmonary Function Test
Saint-Priest-en-Jarez, 42270, France
Hopital Rangueil
Toulouse, 31059, France
Hopital Purpan PPR pole cephalique
Toulouse, 31300, France
Chru Nancy Brabois
Vandœuvre-lès-Nancy, 54511, France
LLC 'Vivamedi'
Tbilisi, 0131, Georgia
LTD Institute of Clinical Cardiology
Tbilisi, 0159, Georgia
JSC Infectious Diseases, AIDS and Clinical Immunology Research Center
Tbilisi, 0160, Georgia
LTD Academician Nikoloz Kipshidze Central University Clinic
Tbilisi, 0160, Georgia
LTD Aversi Clinic
Tbilisi, 0160, Georgia
Malkhaz Katsiashvili Multiprofile Emergency Medicine Center, LTD
Tbilisi, 0172, Georgia
LTD Medical Center "CITO"
Tbilisi, 0179, Georgia
Gastroenterologie Opernstraβe
Kassel, Hassen, 34117, Germany
Universitaetsklinikum Augsburg
Augsburg, 86156, Germany
Staedtisches Klinikum Brandenburg
Brandenburg, 14770, Germany
Prof. Dr. med. Dr. med. Habil. Jens Buhren, FEBO
Frankfurt, 60431, Germany
Agaplesion Markus Krankenhaus
Frankfurt am Main, 60431, Germany
HaFCED e.K. - Hamburgisches Forschungsinstitut für chronisch entzündliche Darmerkrankungen
Hamburg, 20251, Germany
OCT/Ophtalmoscopy address: Universitaetsklinikum Jena
Jena, 07747, Germany
PFT address: Universitaetsklinikum Jena
Jena, 07747, Germany
Universitaetsklinikum Jena
Jena, 07747, Germany
PFT address: Praxis fur Pneumologie und Allergologie
Kassel, 34121, Germany
OCT/Ophtalmoscopy address: Augenarztpraxis Dr. Karola Hassan
Kassel, 34177, Germany
Nordblick Augenklinik
Kiel, 24105, Germany
Universitatsklinikum Schleswig-Holstein- Campus Kiel
Kiel, 24105, Germany
Universitaetsklinikum Leipzig AoeR
Leipzig, 04103, Germany
Dr. Irina Hasewinkel
Nürtingen, 72622, Germany
Medius Klinik Nuertingen
Nürtingen, 72622, Germany
Univerisity General Hospital of Heraklion
Heraklion, Crete, 71500, Greece
University General Hospital of Alexandroupoli
Alexandroupoli, 681 00, Greece
General Hospital of Athens "Evangelismos"
Athens, 10676, Greece
Bugat Pal Korhaz, Gasztroenterologia
Gyöngyös, Heves County, 3200, Hungary
DLCO and ophthalmology tests: Szent Borbala Korhaz
Tatabánya, Komárom-Esztergom, 2800, Hungary
Szent Borbala Korhaz
Tatabánya, Komárom-Esztergom, 2800, Hungary
Bekes Megyei Kozponti Korhaz Dr. Rethy Pal Tagkorhaz, 4. Belgyogyaszat es 2. Gasztroenterologia
Békéscsaba, 5600, Hungary
Clinexpert Egeszsegugyi Szolgaltato es Kereskedelmi Kft. (abbreviated name: Clinexpert Kft.)
Budapest, 1033, Hungary
Ophthalmology procedures: Magyar Honvedseg Egeszsegugyi Kozpont
Budapest, 1062, Hungary
Pulmonary procedures: Vasutegeszsegugyi Nonprofit Kozhasznu K ft.
Budapest, 1062, Hungary
Semmelweis Egyetem, Belgyogyaszati es Hematologiai Klinika
Budapest, 1088, Hungary
Ophthalmology, OCT: Medicover Zrt.
Budapest, 1134, Hungary
Pannonia Maganorvosi Centrum
Budapest, 1136, Hungary
Chest X-ray: XIII. keruleti Egeszsegugyi Szolgalat Kozhasznu Nonprofit Kft.
Budapest, 1139, Hungary
Surat Institute of Digestive Sciences
Surat, Gujarat, 395002, India
Fortis Memorial Research Institute
Gurugram, Haryana, 122002, India
Midas Multispeciality Hospital Pvt. Ltd
Nagpur, Maharashtra, 440010, India
S. R. Kalla Memorial Gastro & General Hospital
Jaipur, Rajasthan, 302001, India
Aster Medcity, Aster DM Healthcare Ltd.
Kochi, 682027, India
HaEmek Medical Center
Afula, 1834111, Israel
Shaare Zedek Medical Center
Jerusalem, 9103102, Israel
Chaim Sheba Medical Center
Ramat Gan, 5262000, Israel
Tel Aviv Sourasky Medical Center
Tel Aviv, 6423906, Israel
IRCCS Ospedale Casa Sollievo della Sofferenza
San Giovanni Rotondo, Foggia, 71013, Italy
OCT/ PFT/ Endoscopy address: IRCCS Ospedale Casa Sollievo della Sofferenza
San Giovanni Rotondo, Foggia, 71013, Italy
IRCCS Humanitas Research Hospital
Rozzano, Milano, 20089, Italy
ASST Rhodense - Pneumology Unit
Garbagnate Milanese, Milan, 20024, Italy
ASST Rhodense, U.O.C. Gastroenterologia ed Endoscopia Digestiva
Milan, Milan, 20017 Rho, Italy
ASST Rhodense - Ophthalmology Unit
Rho, Milan, 20017, Italy
Ospedale San Raffaele
Milan, MI, 20132, Italy
OCT/ PFT/ Endoscopy address: IRCCS Ospedale Sacro Cuore Don Calabria
Negrar, Verona, 37024, Italy
Azienda Ospedaliera Ospedale Cannizzaro
Catania, 829-95126, Italy
A.O. Mater Domini, U.O. Fisiopatologia Apparato Digerente Campus Universitario "Salvatore Venuta"
Catanzaro, 88100, Italy
A.O. Mater Domini, U.O. Fisiopatologia Apparato Digerente
Catanzaro, 88100, Italy
CAMPUS GERMANETO Magazzino farmaci e dispositivi medici, uffici
Catanzaro, 88100, Italy
Fondazione IRCCS Policlinico San Matteo - Centro per lo Studio e la Cura delle Amiloidosi Sistemiche
Pavia, 27100, Italy
PFT address: Azienda Ospedaliero-Universitaria Sant' Andrea UOC Pneumologia
Rome, 00189, Italy
IRCCS Ospedale Sacro Cuore Don Calabria
Verona, 37024, Italy
OCT/PFT/Endoscopy address: CRC - Cenro Ricerche Cliniche di Verona
Verona, 37134, Italy
Kokikai Tsujinaka Hospital Kashiwanoha
Kashiwa-shi, Chiba, 277-0871, Japan
Ishii Eye Clinic
Nagareyama-shi, Chiba, 270-0116, Japan
Hospital of the university of occupational and environmental health
Kitakyushu-shi, Fukuoka, 807-8555, Japan
Kitakyushu Municipal Medical Center
Kitakyusyu-shi, Fukuoka, 802-8561, Japan
Matsumoto Eye Clinic
Toride-shi, Ibaraki, 302-0014, Japan
Kagoshima Kouseiren Hospital
Kagoshima, Kagoshima-ken, 890-0062, Japan
Jiaikai Idzuro Imamura Hospital
Kagoshima, Kagoshima-ken, 892-0824, Japan
Sameshima Eye Clinic
Kagoshima, Kagoshima-ken, 892-0825, Japan
Sameshima Hospital
Kagoshima, Kagoshima-ken, 892-0846, Japan
Japanese Red Cross Kumamoto Hospital
Kumamoto, Kumamoto, 861-8520, Japan
Saga University Hospital
Saga, Saga-ken, 849-8501, Japan
Japan Community Health care Organization Tokyo Yamate Medical Center
Shinjuku-ku, Tokyo, 169-0073, Japan
Saint George University Hospital Medical Center
Beirut, 1100 2807, Lebanon
Rafik Hariri University Hospital
Beirut, 113-6044, Lebanon
Hotel Dieu de France Hospital
Beirut, 166830, Lebanon
Hammoud Hospital University Medical Center
Saida, Lebanon
Nini Hospital s.a:l
Tripoli, Lebanon
Vilnius University Hospital Santaros Klinikos
Vilnius, LT-08661, Lithuania
University Malaya Medical Centre
Kuala Lumpur, 59100, Malaysia
Centro de Investigacion Medico Biologica Y Terapia Avanzada S.C.
Guadalajara, Jalisco, 44130, Mexico
Global Glaucoma Institute
Guadalajara, Jalisco, 44600, Mexico
Video Endoscopia Americas
Guadalajara, Jalisco, 44600, Mexico
Comercializadora Winco S.A. de C.V.
Guadalajara, Jalisco, 44670, Mexico
Cirugia y Gastro de Veracruz S.A. de C.V. (Progastro)
Boca del Rio, Veracruz, 94299, Mexico
Sanatorio Palmore A.C.
Chihuahua City, 31020, Mexico
Scientia Investigacion Clinica S.C.
Chihuahua City, 31203, Mexico
Vista Lasser de Chihuahua S.C.
Chihuahua City, 31203, Mexico
Servicios Hospitalarios de México, S.A. de C.V.
Chihuahua City, 31283, Mexico
FAICIC S. de R.L. de C.V.
Veracruz, 91900, Mexico
Gabinete de Diagnostico COVADONGA
Veracruz, 91910, Mexico
Alberto Collado Solorzano (Clinica Vision)
Veracruz, 91918, Mexico
"Sf. Arhanghel Mihail" Municipal Clinical Hospital, Department of Gastroenterology
Chisinau, 2005, Moldova
PMSI Republican Clinical Hospital "Timofei Mosneaga", Department of Colorectal Surgery
Chisinau, MD2025, Moldova
PMSI Republican Clinical Hospital "Timofei Mosneaga", Department of Gastroenterology
Chisinau, MD2025, Moldova
PMSI Republican Clinical Hospital "Timofei Mosneaga", Outpatient Department
Chisinau, MD2025, Moldova
Academic Medical Centre
Amsterdam, 1105 AZ, Netherlands
UMC Utrecht
Utrecht, 3584 CX, Netherlands
NSZOZ Termedica
Poznan, Greater Poland Voivodeship, 60-681, Poland
Centrum Pulmonologii i Torakochirurgii w Bystrej (DLCO)
Bystra, 43-360, Poland
Specjalistyczne Gabinety Lekarskie LANDA
Karkow, 31-156, Poland
Centre De La Vision Centrum Okulistyczne(OCT, Ophthalmoscopy)
Krakow, 30-033, Poland
Medicina (Endoscopy)
Krakow, 30-307, Poland
Centrum Medyczne EVITA(Endoscopy)
Krakow, 31-153, Poland
(Centrum Medyczne Ksiezy Mlyn (OCT and Ophthalmoscopy)
Lodz, 90-338, Poland
Centrum Medyczne "Ksiezy Mlyn" (OCT, Ophtalmoscopy)
Lodz, 90-338, Poland
AMICARE Sp. z o.o. sp.k
Lodz, 90-644, Poland
IP Clinic Sp. z o.o.
Lodz, 90-752, Poland
Centra Medyczne Medyceusz (DLCO)
Lodz, 91-053, Poland
Salve Health Care Sp. o.o., (PFT and Endoscopy)
Lodz, 92-551, Poland
Wojewodzkie Wielospecjalistyczne Centrum Onkologii i Traumatolog i im. M. Kopernika w Lodzi
Lodz, 93-513, Poland
Allmedica Badania Kliniczne Sp. z o.o. Sp. k.
Nowy Targ, 34-400, Poland
Medicome Sp. Z O.O
Oświęcim, 32-600, Poland
Przychodnia Okulistyczna "Oculus" Barbara Cybulska (OCT, Ophtalmoscopy)
Piotrkow Trybunalski, 97-300, Poland
Samodzielny Szpital Wojewodzki im. Mikolaja Kopernika (Endoscopy)
Piotrkow Trybunalski, 97-300, Poland
Trialmed CRS
Piotrokow Trybunalski, 97-300, Poland
Solurmed Centrum Medyczne
Poznan, 60-529, Poland
OCU Service Mikolaj Meller Sp.j.(OCT, Ophtalmoscopy)
Poznan, 60-538, Poland
Kliniczny Szpital Wojewodzki Nr 1 im. Fryderyka Chopina w Rzeszowie (Ophthalmpscopy)
Rzeszów, 35-055, Poland
Podkarpackie Centrum Chorob Plue w Rzeszowie (DLCO)
Rzeszów, 35-241, Poland
Centrum Medyczne Medyk
Rzeszów, 35-326, Poland
Strzegomskie Centrum Medyczno - Diagnostyczne Sp. z o.o. (Endoscopy)
Strzegom, 58-150, Poland
Centrum Medyczne EZ-MEDICA (OCT, Ophtalmoscopy)
Swidnica, 58-100, Poland
DC-MED
Swidnica, 58-100, Poland
Szpital "Latawiec" -Poradnia Gruzlicy i Chorob Pluc (PFT)
Swidnica, 58-100, Poland
Centrum Zdrowia MDM (OCT,opthalmoscopy)
Warsaw, 00-631, Poland
Centrum Zdrowia MDM
Warsaw, 00-635, Poland
Instytut Gruzlicy i Chorob Pluc(DLCO)
Warsaw, 01-138, Poland
Endoterapia PFG (Endoscopy)
Warsaw, 02-653, Poland
Instytut Oka (OCT, Ophtalmoscopy)
Warsaw, 02-653, Poland
Specjalistyczne Gabinety Lekarskie Body Clinic
Warsaw, 03-712, Poland
Centrum Okulistyczne JASKRA (OCT, Ophthalmoscopy)
Warsaw, 03-731, Poland
Wojskowy lnstytut Medyczny (PFT)
Warsaw, 04-141, Poland
EuroMediCare Szpital Specjalistyczny z Przychodniit (Endoscopy)
Wroclaw, 60-681, Poland
Spitalul Clinic Judetean de Urgenta Cluj Napoca
Cluj-Napoca, JUD. CLUJ, 400006, Romania
Centrul de Diagnostic si Tratament Affidea, Specialitatea Medicina Interna
Constanța, Jud.constanta, 900591, Romania
SC Centrul Medical Medicum SRL, Specialitatea Gastroenterologie
Bucharest, 012015, Romania
Institutul Clinic Fundeni, Centrul de Gastroenterologie si Hepatologie
Bucharest, 022328, Romania
LLC "Polyclinic of ultrasonography 4D"
Pyatigorsk, Stavropol Kray, 357502, Russia
SAIH "Kemerovo Regional Clinical Hospital"
Kemerovo, 650066, Russia
LLC "SibNovoMed"
Novosibirsk, 630005, Russia
Gastrocenter
Novosibirsk, 630007, Russia
LLC "Novosibirskiy Gastrocentr''
Novosibirsk, 630007, Russia
Hospital #12
Novosibirsk, 630084, Russia
LLC "Siberian Center for Prevention and Treatment of Myopia Eye"
Novosibirsk, 630091, Russia
Joint Stock Company Medical Center "AVICENNA"
Novosibirsk, 630099, Russia
BHI of Omsk region "Clinical oncology dispensary"
Omsk, 644013, Russia
Clinicodiagnostic Center "Ultramed"
Omsk, 644024, Russia
Medical center "Intervzglyad"
Omsk, 644070, Russia
FSBI of Higher Education " North-Western Medical University n.a.I.I. Mechnikov '' of MoH RF
Saint Petersburg, 191015, Russia
FSBI of Higher Education "North-Western Medical University n.a.I.I. Mechnikov'' of MoH RF
Saint Petersburg, 195067, Russia
Autonomous Noncommercial Medical Organization "Stavropol Regional Clinical
Stavropol, 355017, Russia
Clinical Center Zvezdara
Belgrade, 11000, Serbia
Fakultna nemocnica s poliklinikou F.D.Roosevelta
Banská Bystrica, 975 17, Slovakia
ALIAN. s.r.o .. Ambulancia vnutorneho lekarstva
Bardejov, 08501, Slovakia
ENDOMED, s.r.o. Gastroenterologicka ambulancia
Košice, 040 13, Slovakia
Opthalmology outpatient clinic, MUDr. Michal Popovec, s.r.o.
Lipany, 082 71, Slovakia
KM Management spol.s.r.o. Gastroenterologicke a hepatologicke centrum
Nitra, 949 01, Slovakia
GASTRO I., s.r.o. Gastroenterologicka ambulancia
Prešov, 080 01, Slovakia
GASTRO LM s.r.o., Gastroenterologicka ambulancia
Prešov, 080 01, Slovakia
Pneumology: PULMO, s.r.o.
Prešov, 080 01, Slovakia
X-ray: FNsP J.A. Reimana Presov
Prešov, 080 01, Slovakia
Dr W Simmonds (Gastroenterology Department)
Bloemfontein, Free State, 9301, South Africa
Dr K Rahman (OTC and Opthalmoscopy)
Benoni, Gauteng, 1500, South Africa
Lakeview Hospital radiology (Radiology)
Benoni, Gauteng, 1500, South Africa
Worthwhile Clinical trials (PFT)
Benoni, Gauteng, 1500, South Africa
Worthwhile Clinical Trials
Benoni, Gauteng, 1501, South Africa
Dr E Meyer & Partners, Centurion Eye Hospital (OTC and Opthalmoscopy)
Centurion, Gauteng, 0157, South Africa
Dr Jorg Reichenberger (Endoscopy)
Centurion, Gauteng, 0157, South Africa
Drs Burger Radiologists Inc (X-ray/CT)
Centurion, Gauteng, 0157, South Africa
Johese Clinical Research, Unitas Hospital
Centurion, Gauteng, 0157, South Africa
WITS Clinical Research
Johannesburg, Gauteng, 2193, South Africa
Burger Radiology (Radiology)
Kempton Park, Gauteng, 1619, South Africa
Clinresco Centres (Pty) Ltd
Kempton Park, Gauteng, 1619, South Africa
Dr KJP Lubuya (OCT and Opthalmology)
Kempton Park, Gauteng, 1619, South Africa
Prof O Mwantembe (Endoscopy)
Kempton Park, Gauteng, 1619, South Africa
Emmed Research
Pretoria, Gauteng, 0002, South Africa
Dr K Rahman(OTC and Opthalmoscopy)
Springs, Gauteng, 1559, South Africa
Dr I Moola (Endoscopy)
Sunninghill, Gauteng, 2196, South Africa
Dr Peter Chapman (PFT + DLCO)
Cape Town, Western Cape, 7405, South Africa
Dr Chris Stander (OCT)
Cape Town, Western Cape, 7441, South Africa
Morton & Partners Radiologists (Radiology)
Cape Town, Western Cape, 7441, South Africa
Spoke Research Inc. Room 109
Cape Town, Western Cape, 7441, South Africa
DongGuk University ilsan Hospital
Goyang-si, Gyeonggi-do, 10326, South Korea
Kyungpook National University Chilgok Hospital
Daegu, 41404, South Korea
Endoscopy Facility in kyungpook National University Hospital
Daegu, 41944, South Korea
Kyungpook National University Hospital
Daegu, 41944, South Korea
OCT Facility In kyungpook National University Hospital
Daegu, 41944, South Korea
PFT Facility in Kyungpook National University Hospital
Daegu, 41944, South Korea
The Catholic University of Korea, Daejeon St. Mary's Hospital
Daejeon, 34943, South Korea
Gachon university Gil Medical Center
Incheon, 21565, South Korea
CHA University Bundang CHA Hospital
Seongnam-si, 13496, South Korea
Kyunghee University Medical Center
Seoul, 02447, South Korea
Gangnam Severance Hospital, Yonsei University Health System
Seoul, 06273, South Korea
Chung-Ang University Hospital
Seoul, 06973, South Korea
Hospital General de Tomelloso
Tomellso, Ciudad REAL, 13700, Spain
Hospital Universitario de Gran Canaria Dr. Negrin
Las Palmas de Gran Canaria, 35010, Spain
Hospital Universitario La Paz
Madrid, 28046, Spain
Inselspital Bern
Bern, 3010, Switzerland
OCT/Ophtalmoscopy: Berner Augenklinik am Lindenhofspital
Bern, 3012, Switzerland
Hacettepe University Medical Faculty
Ankara, 06100, Turkey (Türkiye)
Gazi University Medical Faculty
Ankara, 06500, Turkey (Türkiye)
T.C. Saglik Bakanligi Ankara Sehir Hastanesi
Ankara, 06800, Turkey (Türkiye)
Saglik Bilimleri Universitesi Antalya Egitim ve Arastirma Hastanesi
Antalya, 07100, Turkey (Türkiye)
Ege Universitesi Tip Fakultesi Hastanesi
Izmir, 35100, Turkey (Türkiye)
Kocaeli University Research and Training Hospital
Kocaeli, 41380, Turkey (Türkiye)
Mersin University Faculty of Medicine
Yenişehir, 33343, Turkey (Türkiye)
Llc "Ldts Skaymed'
Kharkiv, 61022, Ukraine
LLC "EyeQClinic"
Kharkiv, 61024, Ukraine
Communal Non-commercial Enterprise Prof. O.O. Shalimov City Clinical Hospital #2 of Kharkiv
Kharkiv, 61037, Ukraine
Llc "Medical Center Oftalmika"
Kharkiv, 61045, Ukraine
Municipal Health Care "Kharkiv City Hospital Ambulance and Emergency Medical care
Kharkiv, 61103, Ukraine
Communal Non-commercial Enterprise City Clinical Hospital #13 of Kharkiv City Council
Kharkiv, 61124, Ukraine
Medical Center of Limited Liability Company Harmoniia Krasy
Kyiv, 01135, Ukraine
Med Center 'Ok!Clinic+' of Comp with limited liability "Int Inst of Clin Research", Unit of Gastro
Kyiv, 02091, Ukraine
Private Enterprise "Clinic Medicom"
Kyiv, 04210, Ukraine
CE Volyn Reg Clinical Hospital ofVolyn Reg Council, Surgical (Endocrine and Abdominal Pathology)
Lutsk, 43005, Ukraine
Private Enterprise Diagnostic Center "Mediscan"
Vinnytsia, 21000, Ukraine
Medical Center of LLC Health Clinic, Medical Clinical Research Center, Unit of Gastroenterology,
Vinnytsia, 21009, Ukraine
CNE of M.I. Pyrohov Vinnytsia Regional Clinical Hospital of Vinnytsia Regional Council, Reg
Vinnytsia, 21018, Ukraine
Scientific and Research Institute of Invalid Rehabilitation (Educational, Scientific and Treatment
Vinnytsia, 21029, Ukraine
Royal Liverpool University Hospital
Liverpool, L7 8XP, United Kingdom
Central Middlesex Hospital
London, NW10 7NS, United Kingdom
Guys & St Thomas Hospital
London, SE1 9RT, United Kingdom
Quadram Institute Clinical Research Facility
Norwich, NR4 7UQ, United Kingdom
Related Publications (1)
Dubinsky MC, Wu J, McDonnell A, Lazin K, Goetsch M, Branquinho D, Modesto I, Armuzzi A. Low Incidence of Macular Edema and Other Ocular Events in the Etrasimod Development Program. J Crohns Colitis. 2025 May 8;19(5):jjae173. doi: 10.1093/ecco-jcc/jjae173.
PMID: 39575597DERIVED
Related Links
MeSH Terms
Conditions
Interventions
Condition Hierarchy (Ancestors)
Study Officials
- STUDY DIRECTOR
Pfizer CT.gov Call Center
Pfizer
Study Design
- Study Type
- interventional
- Phase
- phase 3
- Allocation
- RANDOMIZED
- Masking
- DOUBLE
- Who Masked
- PARTICIPANT, INVESTIGATOR
- Purpose
- TREATMENT
- Intervention Model
- PARALLEL
- Sponsor Type
- INDUSTRY
- Responsible Party
- SPONSOR
Study Record Dates
First Submitted
November 20, 2019
First Posted
November 21, 2019
Study Start
January 6, 2020
Primary Completion
April 23, 2025
Study Completion
June 9, 2025
Last Updated
July 16, 2025
Record last verified: 2025-07
Data Sharing
- IPD Sharing
- Will share
Pfizer will provide access to individual de-identified participant data and related study documents (e.g. protocol, Statistical Analysis Plan (SAP), Clinical Study Report (CSR)) upon request from qualified researchers, and subject to certain criteria, conditions, and exceptions. Further details on Pfizer's data sharing criteria and process for requesting access can be found at: https://www.pfizer.com/science/clinical\_trials/trial\_data\_and\_results/data\_requests.