Key Highlights

Risk & Performance

Pipeline Risk Assessment

Pipeline Risk Assessment

Based on historical performance

High Risk

Score: 70/100

Failure Rate

36.4%

4 terminated/withdrawn out of 11 trials

Success Rate

55.6%

-30.9% vs industry average

Late-Stage Pipeline

27%

3 trials in Phase 3/4

Results Transparency

160%

8 of 5 completed trials have results

Key Signals

1 recruiting8 with results

Enrollment Performance

Analytics

Phase 2
8(72.7%)
Phase 3
3(27.3%)
11Total
Phase 2(8)
Phase 3(3)

Activity Timeline

Global Presence

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Clinical Trials (11)

Showing 11 of 11 trials
NCT05287126Phase 2Recruiting

A Study to Evaluate Etrasimod Treatment in Adolescents With Ulcerative Colitis

Role: collaborator

NCT03950232Phase 3Active Not Recruiting

An Extension Study for Treatment of Moderately to Severely Active Ulcerative Colitis

Role: collaborator

NCT04173273Phase 3Terminated

A Study Evaluating the Efficacy and Safety of Oral Etrasimod in the Treatment of Adult Participants With Moderately to Severely Active Crohn's Disease

Role: collaborator

NCT04607837Phase 2Completed

Etrasimod Versus Placebo for the Treatment of Moderately Active Ulcerative Colitis

Role: collaborator

NCT05061446Phase 2Completed

Etrasimod Dose-Ranging Versus Placebo as Induction Therapy Study in Adult Japanese Subjects With Moderately to Severely Active Ulcerative Colitis

Role: collaborator

NCT04556734Phase 2Completed

Safety and Efficacy of Oral Etrasimod in Adult Participants With Moderate-to-Severe Alopecia Areata

Role: collaborator

NCT04682639Phase 2Completed

A Study to Assess the Safety and Efficacy of Oral Etrasimod in Adult Participants With Eosinophilic Esophagitis

Role: collaborator

NCT04915950Phase 2Terminated

A Study to Assess the Effect of Oral Temanogrel on Digital Blood Flow in Adult Participants With Raynaud's Phenomenon Secondary to Systemic Sclerosis

Role: collaborator

NCT04848220Phase 2Terminated

A Study Evaluating the Safety, Tolerability, and Effect on Microvascular Obstruction of Intravenous Temanogrel in Adult Participants Undergoing Percutaneous Coronary Intervention

Role: collaborator

NCT05139615Phase 2Terminated

A Study to Assess the Hemodynamic Effects, Safety, Tolerability, and Pharmacokinetics of Intravenous APD418 in Adult Participants With Heart Failure With Reduced Ejection Fraction

Role: collaborator

NCT04706793Phase 3Completed

Oral Etrasimod Versus Placebo for the Treatment of Moderately to Severely Active Ulcerative Colitis in Adult Japanese Participants (ELEVATE UC 40 JAPAN)

Role: collaborator

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