Effect of Low Doses of Vitamin C on Salivary Cortisol , Heart Rate , Blood Pressure During Group Presentation

NCT04135378 | Completed Phase 4

• 1 other identifier: KufaU2
• Study Type: interventional
• Target: 90
• Locations: 1 country
• Sites: 1

Brief Summary

Vitamin C (ascorbic acid) is a well-known antioxidant that is involved in anxiety, stress, depression, fatigue and mood state in humans . The purpose of this study is to investigate the effect of low doses of vitamin C on decreasing the level of public speaking stress in term of salivary cortisol , blood pressure (systolic and diastolic) and heart rate . A purposive sample of (90) were included in this randomized placeboled trial study (60 students were given 500 mg of vitamin c per day for one week a group presentation while 30 other students were given placebo for one week before a group presentation) . Salivary cortisol was measured by means of commercial immunoenzymatic kits . Blood pressure (systolic and diastolic) and heart rate were measured immediately before and after presentation .

Conditions

Stress, Psychological

Keywords

vitamin C , salivary cortisol , heart rate , blood pressure

Outcome Measures

Primary Outcomes (1)

• Cortisol

  levels of cortisol in saliva between 3-19 microg/l

  for six months

Study Arms (2)

student- ascorbic acid

EXPERIMENTAL

Student that have presentation given ascorbic acid ( 500 mg per day) for one week before presentation .

Drug: ascorbic acid

Control- ascorbic acid like

PLACEBO COMPARATOR

ascorbic acid like placebo for one week before presentation

Other: placebo

Interventions

ascorbic acid DRUG

Study Group :- ascorbic acid ( 500 mg per day) for one week before presentation

Also known as: vitamin C

student- ascorbic acid

placebo OTHER

:- included 30 students given placebo for one week before presentation.

Control- ascorbic acid like

Eligibility Criteria

• Age: 20 Years - 60 Years
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64)

You may qualify if:

• \- students have a presentation

Sponsors & Collaborators

• Kufa University: lead

Study Sites (1)

Kufa University

Najaf, Kufa, 0964, Iraq

Location

MeSH Terms

Conditions

Stress, Psychological

Interventions

Ascorbic Acid

Condition Hierarchy (Ancestors)

Behavioral Symptoms; Behavior

Intervention Hierarchy (Ancestors)

Sugar Acids; Acids, Acyclic; Carboxylic Acids; Organic Chemicals; Hydroxy Acids; Carbohydrates

Study Officials

• Ali A Al-fahham, Asst. Prof.

  Kufa University

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: interventional
• Phase: phase 4
• Allocation: RANDOMIZED
• Masking: NONE
• Purpose: TREATMENT
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Assistance Professor

Model Details: Experimental randomized placebo trial study approach was designed to meet the previously mentioned objectives of the current study. The period of the study is from 1st November 2018 to 20th April 2019. A random sample of (90) students was taken in this study .

Study Record Dates

• First Submitted: October 16, 2019
• First Posted: October 22, 2019
• Study Start: November 1, 2018
• Primary Completion: March 1, 2019
• Study Completion: April 20, 2019
• Last Updated: October 22, 2019

Record last verified: 2019-10

Data Sharing

• IPD Sharing: Will not share

Locations

IR (1)