Success Metrics

Clinical Success Rate
75.4%

Based on 49 completed trials

Completion Rate
75%(49/65)
Active Trials
9(9%)
Results Posted
49%(24 trials)
Terminated
16(16%)

Phase Distribution

Ph phase_1
25
25%
Ph phase_2
31
31%
Ph phase_3
9
9%
Ph early_phase_1
5
5%
Ph not_applicable
13
13%
Ph phase_4
14
14%

Phase Distribution

30

Early Stage

31

Mid Stage

23

Late Stage

Phase Distribution97 total trials
Early Phase 1First-in-human
5(5.2%)
Phase 1Safety & dosage
25(25.8%)
Phase 2Efficacy & side effects
31(32.0%)
Phase 3Large-scale testing
9(9.3%)
Phase 4Post-market surveillance
14(14.4%)
N/ANon-phased studies
13(13.4%)

Highest Phase Reached

Phase 4

Trial Status & Enrollment

Completion Rate

66.2%

49 of 74 finished

Non-Completion Rate

33.8%

25 ended early

Currently Active

9

trials recruiting

Total Trials

100

all time

Status Distribution
Active(12)
Completed(49)
Terminated(25)
Other(14)

Detailed Status

Completed49
Terminated16
unknown12
Withdrawn9
Recruiting6
Not yet recruiting3

Development Timeline

Analytics

Development Status

Total Trials
100
Active
9
Success Rate
75.4%
Most Advanced
Phase 4

Trials by Phase

Early Phase 15 (5.2%)
Phase 125 (25.8%)
Phase 231 (32.0%)
Phase 39 (9.3%)
Phase 414 (14.4%)
N/A13 (13.4%)

Trials by Status

suspended22%
terminated1616%
unknown1212%
recruiting66%
not_yet_recruiting33%
completed4949%
withdrawn99%
active_not_recruiting33%

Recent Activity

Clinical Trials (100)

Showing 20 of 100 trialsScroll for more
NCT03418038Phase 2

Ascorbic Acid and Chemotherapy for the Treatment of Relapsed or Refractory Lymphoma, CCUS, and Chronic Myelomonocytic Leukemia

Recruiting
NCT04756063Phase 4

Parenteral Ascorbic Acid Repletion in TransplantatIon

Suspended
NCT02905591Phase 2

A Phase 2 Study Adding Ascorbate to Chemotherapy and Radiation Therapy for NSCLC

Active Not Recruiting
NCT05849129Phase 2

Adjunctive Intravenous Ascorbic Acid for Advanced Non-Small Cell Lung Cancer

Recruiting
NCT02344355Phase 2

A Phase 2 Trial of High-Dose Ascorbate in Glioblastoma Multiforme

Active Not Recruiting
NCT04138394Phase 3

VItamin C in Thermal injuRY: The VICToRY Trial

Suspended
NCT04832009Early Phase 1

Reversing Glucose and Lipid-mediated Vascular Dysfunction

Recruiting
NCT01550510Phase 1

Research Study of IV Vitamin C in Combination With Irinotecan vs Irinotecan Alone for Advanced Colorectal CA

Terminated
NCT01555489Phase 2

Assessing the Efficacy and Safety of IV Vitamin C in Combination With Standard Chemotherapy for Pancreatic Ca

Terminated
NCT02896907Early Phase 1

Ascorbic Acid and Combination Chemotherapy in Treating Patients With Locally Advanced or Recurrent Pancreatic Cancer That Cannot Be Removed by Surgery

Completed
NCT06936592Not Applicable

How Can Prefabricated Membranes Load Ascorbic Acid Can Curtail Gingival Recession?

Not Yet Recruiting
NCT04001647Early Phase 1

Targeting ER Stress in Vascular Dysfunction

Terminated
NCT04046094Phase 1

Intravenous (IV) Vitamin C With Chemotherapy for Cisplatin Ineligible Bladder Cancer Patients

Active Not Recruiting
NCT04046861Not Applicable

Influence of High Vitamin C Dose on Lactate During and After Extracorporeal Circulation

Completed
NCT04516681Phase 3

Combination of IV Ascorbic Acid and Adebrelimab in Metastatic Colorectal Cancer

Recruiting
NCT06626113

Transduction of Sympathetic Neural Activity in Human Obesity Without Hypertension

Recruiting
NCT06443151

Role of Endothelial Function in SCI CVD Risk

Recruiting
NCT02420314Phase 2

Pharmacological Ascorbate for Lung Cancer

Completed
NCT06421688Phase 2

Effect of Vitamin C on Postoperative Pulmonary Complications After Intracranial Tumor Surgery

Not Yet Recruiting
NCT06384833Phase 4

Combination of Vitamin C and N-Acetylcysteine to Improve Functional Outcome After Rotator Cuff Repair

Not Yet Recruiting

Drug Details

Intervention Type
DIETARY SUPPLEMENT
Total Trials
100