Correlation Between Blood Pressure, Heart Rate and Plasma Corticotropin, Cortisol Under Surgical Skin Incision

NCT03892538 | Completed

• 1 other identifier: B2018-288R
• Study Type: observational
• Target: 134
• Locations: 1 country
• Sites: 1

Brief Summary

A prospective observational study was conducted to analyze the correlation between systolic blood pressure, diastolic blood pressure, mean arterial pressure，heart rate and plasma corticotropin, cortisol during surgical skin incision.

Conditions

Stress, Psychological

Keywords

Stress; Blood pressure; Heart rate; Corticotropin; Cortisol

Outcome Measures

Primary Outcomes (6)

• systolic blood pressure

  mmHg

  Change from skin incision till 10 minutes after skin incision

• diastolic blood pressure

  mmHg

  Change from skin incision till 10 minutes after skin incision

• mean arterial pressure

  mmHg

  Change from skin incision till 10 minutes after skin incision

• heart rate

  bpm

  Change from skin incision till 10 minutes after skin incision

• corticotropin

  plasma concentration，pg/ml

  Change from skin incision till 10 minutes after skin incision

• cortisol

  plasma concentration，nmol/L

  Change from skin incision till 10 minutes after skin incision

Eligibility Criteria

• Age: 18 Years - 80 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

The enrolled patients were mainly male and the type of surgery was open upper abdominal surgery

You may qualify if:

• the ASA score was from grade I to III,
• aged 18-80 years

You may not qualify if:

• adrenal gland related diseases
• immune system related diseases
• severe cardiovascular and cerebrovascular diseases,
• severe liver and kidney dysfunction
• refuse to participate in this study

Sponsors & Collaborators

• JingCang: lead

Study Sites (1)

Zhongshan Hospital

Shanghai, Shanghai Municipality, 200032, China

Location

Related Publications (20)

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MeSH Terms

Conditions

Stress, Psychological

Condition Hierarchy (Ancestors)

Behavioral Symptoms; Behavior

Study Officials

• Jing Cang, PHD

  Director

  STUDY DIRECTOR

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: SPONSOR INVESTIGATOR
• PI Title: Director

Study Record Dates

• First Submitted: March 13, 2019
• First Posted: March 27, 2019
• Study Start: October 1, 2018
• Primary Completion: March 10, 2019
• Study Completion: March 10, 2019
• Last Updated: March 27, 2019

Record last verified: 2018-10

Locations

CN (1)