GCF
Smoking Effects on GCF GCF IL-17A AND IL-17 Levels and Oxidative Status of Patients Receiving Periodontal Treatment
Sponsor study identifier
observational
30
1 country
1
Study Start
October 10, 2017
Actual (reported)Primary Completion
July 10, 2019
Actual (reported)Study Completion
July 10, 2019
Actual (reported)This study was performed to evaluate the effects of both periodontal treatment and smoking on the gingival crevicular fluid(GCF) levels of interleukin (IL)-17A, IL-17E, Total oxidative stress(TOS) and total antioxidant capasity(TAOC) in smoking and non-smoking patients with severe chronic periodontitis. Systemically healthy 15 smoker,15 non-smoker with chronic periodontitis were attended for the study. Periodontal status were determined by recording periodontal clinical measurements. GCF samples were collected at the baseline, at the end of initial periodontal treatment and 4 weeks after periodontal flap surgery. The data were tested statistically by the Student t and paired sample t tests.
Registry-reported information. Elapsed time and enrollment totals alone do not measure study progress or recruitment pace.
July 10, 2019
Actual (reported)Click on a node to explore related trials.
Dates and qualifiers reported by the registry. Estimated dates do not confirm that a milestone has occurred.
October 10, 2017
Actual (reported)July 10, 2019
Actual (reported)July 10, 2019
Actual (reported)October 2, 2019
Actual (reported)October 3, 2019
Actual (reported)GCF IL-17A VOLUME
IL-17A is a cytokine present in gingival crevicular fluid. Its volume calculated as microliter and changes due to inflammation caused by periodontal disease.
GCF sampling was performed prior to periodontal treatment , 4 weeks after completion of initial periodontal treatment, and 4 weeks after periodontal flap surgery .
GCF IL-17E VOLUME
IL-17E is a cytokine present in gingival crevicular fluid. Its volume calculated as microliter and changes due to inflammation caused by periodontal disease.
GCF sampling was performed prior to periodontal treatment , 4 weeks after completion of initial periodontal treatment, and 4 weeks after periodontal flap surgery .
GCF TOTAL OXIDATIVE STRESS (TOS) LEVEL
TOS is the measurement of oxidative stress amount and given as mmol/L unit. Its amount changes due to inflammation caused by periodontal disease.
GCF sampling was performed prior to periodontal treatment , 4 weeks after completion of initial periodontal treatment, and 4 weeks after periodontal flap surgery .
Individuals clinically diagnosed with chronic periodontitis that smoke recruited for this group.
Individuals clinically diagnosed with chronic periodontitis that don't smoke recruited for this group.
Patients with chronic periodontitis (with an age range of 35 to 60 years) seeking dental treatment at the Periodontology Clinic, School of Dentistry, Ondokuz Mayis University, were included in the present study.
Müge Lütfioğlu
Samsun, Atakum, 55039, Turkey (Türkiye)
MÜGE LÜTFİOĞLU
assoc. prof.
30 participants (actual enrollment reported by the registry).
First Submitted
October 2, 2019
First Posted
October 3, 2019
Study Start
October 10, 2017
Actual (reported)Complex Phytoadaptogenes in Chronic Periodontitis Treatment.
GCF TOTAL ANTIOXIDANT CAPASITY (TAOC)
TAOC is the antioxidant amount measured and given as μmol H2O2 Eq/L unit. Its amount changes due to inflammation caused by periodontal disease.
GCF sampling was performed prior to periodontal treatment , 4 weeks after completion of initial periodontal treatment, and 4 weeks after periodontal flap surgery .
Contact the study team to confirm eligibility.
Primary Completion
July 10, 2019
Actual (reported)Study Completion
July 10, 2019
Actual (reported)Last Updated
October 4, 2019
Record last verified: 2019-10
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Source: ClinicalTrials.gov.
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