Dual Task and Virtuality Training Innovation to Improve Balance, Posture and Gait in Patients With Parkinson Disease

NCT04084743 | Unknown

• 2 other identifiers: MMDU/2019/01U1111-1234-9952
• Study Type: interventional
• Target: 64
• Locations: 0 countries
• Sites: N/A

Brief Summary

Individuals affected with Parkinson disease (PD), are found to be at high risk of motor impairment and non-motor impairment as well. It further leads to affect the quality of life in patients of PD, due to impairments in postural instability, balance impairment and gait disturbances. Hence, various Physiotherapy based rehabilitation is on-demand that improves their quality of life and prognosis. Emerging trends in neuro-rehabilitation are Virtual reality intervention (VRI), that helps the patient to involve in a virtual environment and provide rehabilitation as per need by using different software games. As a result, their balance, posture and gait can improve speedily. In VRI we will be using the latest model of VRI that will include an assessment tool to assess the disability and provide rehabilitation. The cognitive system is also get affected due to physiological changes occur in PD, that leads to impair the other functions during walking such as balance and posture. Because during walking they can not perform dual task orientation to correct their posture and balance. So, dual-task intervention (DTI) is helpful to train them and involve them to participate actively in various activities. In this project, we will develop an innovative rehabilitation technique to improve the posture, balance and gait in patients with PD. It will include VRI and additive DTI that will keep the patients motivated to perform the exercise actively. To assess the problems we will use standard device posturography that will be used before the intervention and after the intervention to identify the changes in their condition. Additionally, we will use some scales as outcome measures to assess the PD, quality of life and gait. Previous studies show that VR games and dual-task intervention training are an effective method to rehabilitate neurological ill patients. During the experiments, both conventional (DTI) and experimental (VRI+ DTI) will be considered.

Conditions

Parkinson Disease

Keywords

Virtual reality; Targeted therapy; Computer game

Outcome Measures

Primary Outcomes (2)

• Parkinson's Disease Questionnaire

  It is a 39 item self report questionnaire, which assess Parkinson disease specific health related quality of the patients. It assess experienced difficulty impact of PD in functioning and well being.

  change will be measured at baseline and after 4 weeks of intervention

• Posturography

  BIORescue (system for sequential posture analysis and rehabilitation- made in France) allows carrying out a comparative assessment supported by many analyses repeated at different times throughout the treatment. Several types of exercises make it possible to work on the reestablishment of the transfer of the support, the stability, the balance, the anticipation of movement, etc.

  change will be measured at baseline and after 4 weeks of intervention

Secondary Outcomes (1)

• UPDRS

  change will be measured at baseline and after 4 weeks of intervention

Study Arms (2)

Virtual reality training and Dual task intervention

EXPERIMENTAL

Cognitive and motor Dual-task intervention and virtual reality training intervention in patients with Parkinson's disease

Other: Virtual reality intervention; Other: Dual task intervention; Other: Conventional physiotherapy

Conventional physiotherapy and Dual task intervention

ACTIVE COMPARATOR

The dual-task intervention without virtual reality training intervention in patients with Parkinson's disease

Other: Virtual reality intervention; Other: Dual task intervention; Other: Conventional physiotherapy

Interventions

Virtual reality intervention OTHER

Virtual reality intervention includes: Maze game software

Conventional physiotherapy and Dual task intervention; Virtual reality training and Dual task intervention

Dual task intervention OTHER

The intervention combined both motor and cognitive training which includes, walking 10 meter (1) Free walking (2) Walking carrying an emptying tray (3) Walking carrying a tray with 4 empty glasses (4) Digit calculations (Counting forward and backward, addition, subtraction, multiplication and division) during walking.

Conventional physiotherapy and Dual task intervention; Virtual reality training and Dual task intervention

Conventional physiotherapy OTHER

1. Gait training in parallel bar 2. Balance activities which includes, a. Forward direction activity b. Backward direction activity c. Sideways direction activity

Conventional physiotherapy and Dual task intervention; Virtual reality training and Dual task intervention

Eligibility Criteria

• Age: 45 Years - 70 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• Idiopathic PD (according to the united kingdom parkinson's disease society brain bank criteria)
• Hoehn and Yahr stage III
• Able to walk without any assistance
• Age between 45-70
• Both sex male and female

You may not qualify if:

• Any neurological disease other than PD
• Vestibular disorders
• Musculoskeletal impairments that could affect gait
• Inability to stand and walk unassisted
• Uncooperative patients

Sponsors & Collaborators

• Asir John Samuel: lead

Related Publications (4)

• Hubbard B, Pothier D, Hughes C, Rutka J. A portable, low-cost system for posturography: a platform for longitudinal balance telemetry. J Otolaryngol Head Neck Surg. 2012 Apr;41 Suppl 1:S31-5.

  PMID: 22569047 RESULT

• Abdolahi A, Scoglio N, Killoran A, Dorsey ER, Biglan KM. Potential reliability and validity of a modified version of the Unified Parkinson's Disease Rating Scale that could be administered remotely. Parkinsonism Relat Disord. 2013 Feb;19(2):218-21. doi: 10.1016/j.parkreldis.2012.10.008. Epub 2012 Oct 25.

  PMID: 23102808 RESULT

• Reinkensmeyer DJ, Boninger ML. Technologies and combination therapies for enhancing movement training for people with a disability. J Neuroeng Rehabil. 2012 Mar 30;9:17. doi: 10.1186/1743-0003-9-17.

  PMID: 22463132 RESULT

• Bisson E, Contant B, Sveistrup H, Lajoie Y. Functional balance and dual-task reaction times in older adults are improved by virtual reality and biofeedback training. Cyberpsychol Behav. 2007 Feb;10(1):16-23. doi: 10.1089/cpb.2006.9997.

  PMID: 17305444 RESULT

Related Links

• Related Info
• Related Info
• Related Info
• Related Info

MeSH Terms

Conditions

Parkinson Disease

Condition Hierarchy (Ancestors)

Parkinsonian Disorders; Basal Ganglia Diseases; Brain Diseases; Central Nervous System Diseases; Nervous System Diseases; Movement Disorders; Synucleinopathies; Neurodegenerative Diseases

Study Officials

• Adarsh K Srivastav, MPT

  Maharishi Markandeshwar Institute of Physiotherapy and Rehabilitation

  PRINCIPAL INVESTIGATOR

Central Study Contacts

Asir J Samuel, MPT, (Ph.D)

CONTACT

8059930222; asirjohnsamuel@mmumullana.org

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: DOUBLE
• Who Masked: PARTICIPANT, OUTCOMES ASSESSOR
• Purpose: TREATMENT
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: SPONSOR INVESTIGATOR
• PI Title: Associate Professor

Study Record Dates

• First Submitted: August 31, 2019
• First Posted: September 10, 2019
• Study Start: June 2, 2022
• Primary Completion: October 31, 2023
• Study Completion: December 30, 2023
• Last Updated: October 1, 2021

Record last verified: 2021-09

Data Sharing

• IPD Sharing: Will not share