Motor Learning-based Clinical Pilates Rehabilitation Protocol for Patients with Parkinson's Disease

NCT05899426 | Completed DMC

• 1 other identifier: BAYEK022.05
• Study Type: interventional
• Target: 32
• Locations: 1 country
• Sites: 1

Brief Summary

Individuals with Parkinson's disease demonstrate impaired motor learning, including a slower acquisition rate and poor retention, which may result from deficits in cognitive function, especially executive function. Considering the reduced motor learning ability in this patient group, exercises should be designed with a focus on strengthening sensory inputs and basic functional training. Therefore, the investigators established this program according to previous experience published study \[NCT04063605\]. Therefore, the feasibility of this rehabilitation protocol, which combines motor learning and clinical pilates principles and is adapted to the needs of individuals with Parkinson's disease, will be examined.

Conditions

Parkinson Disease

Keywords

Parkinson Disease; Exercise

Outcome Measures

Primary Outcomes (3)

• Nelson Foot Reaction Test

  This test is measured using a ruler and this gives the simple reaction time. The participant sits against the wall with the toe at a distance of 2.5 cm and the heel at a distance of 5 cm from the wall. The test administrator holds the reaction ruler between the wall and the participant's foot and releases the ruler as soon as the participant is ready. The participant tries to hold the falling ruler by squeezing it against the wall. It will be measured 20 times. Five best and five worst values will be discarded and the average of the remaining measurement will be taken.

  5 minutes

• Gait and Balance Scale (Untimed Tasks)

  Gait and Balance Scale (GABS) consists of historical information and examination of 14 different gait and balance parameters designed to assess the severity of these functional domains. Thirty-five patients with Parkinson's disease (PD), Hoehn and Yahr stages 1 - 3, were tested. Items 1 to 17 GABS are scored on a scale of 0 to 4 (0 being normal and 4 being the worst). Items 18- 24 are scored on a scale 0 to 1 or 0 to 2 (0 being normal and 1 or 2 being abnormal).

  15 minutes

• Gait and Balance Scale (Timed Tasks - Cadence)

  Gait and Balance Scale (GABS) consists of timed tasks to assess gait speed and the 'up-and-go' test. Timed tasks provide valuable information about the gait cycle by measuring speed of walking, variation between the normal and fast gait speed, stand-walk-sit time and cadence.

  2 minutes

Secondary Outcomes (4)

• Functional reach test

  5 minutes

• Timed-up and Go test

  5 minutes

• Berg Balance Scale

  15 minutes

• The Unified Parkinson's Disease Rating Scale (UPDRS) III. Subscale

  15 minutes

Study Arms (2)

Motor learning based clinical pilates

EXPERIMENTAL

Participants in this group will receive training for 60 minutes 2 times a week for 12 weeks and will be followed up with the same assessments at the 3rd months after the treatment.

Other: motor learning based clinical pilates

Conventional Physiotherapy

ACTIVE COMPARATOR

Participants in this group will receive training for 60 minutes 2 times a week for 12 weeks and will be followed up with the same assessments at the 3rd months after the treatment.

Other: Conventional Physiotherapy

Interventions

motor learning based clinical pilates OTHER

The exercises will be created as function and goal. At least one stimulus will be given during each exercise (visual, tactile, auditory or vestibular). 2 different levels were determined for 3 months of treatment, according to the months. As the level increased, the intensity of the exercise increased. In general, the exercise intensity was increased according to the against gravity and the decreasing in the support area.

Also known as: Parkinsonpilates

Motor learning based clinical pilates

Conventional Physiotherapy OTHER

This exercise program will include strengthening, stretching, posture exercises, balance and gait exercises. Aim is to improve muscle strength and prevent shortness of muscles. Also, balance and gait exercise aim to improve walking capacity.

Also known as: Control group

Conventional Physiotherapy

Eligibility Criteria

• Age: 45 Years - 80 Years
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• Having modified Hoehn \& Yahr Scale grade 2-3 symptoms
• Be over 45 years old
• Having a score of 24 or 24\< on the Mini Mental test
• To be able to read and write in Turkish
• Having at least 2 years Parkinson's Disease

You may not qualify if:

• Serious mental and psychological disorder
• Significant musculoskeletal disorders
• Lower extremity deformation
• Having another neurological disease
• Drug or dose change during treatment

Sponsors & Collaborators

• European University of Lefke: lead

Study Sites (1)

European University of Lefke

Mersin, Turkey (Türkiye)

Location

MeSH Terms

Conditions

Parkinson Disease; Motor Activity

Interventions

Control Groups

Condition Hierarchy (Ancestors)

Parkinsonian Disorders; Basal Ganglia Diseases; Brain Diseases; Central Nervous System Diseases; Nervous System Diseases; Movement Disorders; Synucleinopathies; Neurodegenerative Diseases; Behavior

Intervention Hierarchy (Ancestors)

Epidemiologic Research Design; Epidemiologic Methods; Investigative Techniques; Research Design; Methods

Study Officials

• Beliz Belgen Kaygısız, PT, PhD

  European University of Lefke

  PRINCIPAL INVESTIGATOR

• Fahriye Çoban, PT, MSc

  European University of Lefke

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: NONE
• Purpose: TREATMENT
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Model Details: 2 groups will receive different exercise program for 12 weeks.

Study Record Dates

• First Submitted: May 28, 2023
• First Posted: June 12, 2023
• Study Start: June 25, 2023
• Primary Completion: March 20, 2024
• Study Completion: June 15, 2024
• Last Updated: September 19, 2024

Record last verified: 2024-08

Data Sharing

• IPD Sharing: Will not share

Locations

TU (1)