Multisensory Training in PD

NCT05027555 | Unknown

• 1 other identifier: 21MMHIS153e
• Study Type: interventional
• Target: 40
• Locations: 0 countries
• Sites: N/A

Brief Summary

People with Parkinson's disease (PD) were characterized by many motor symptoms, including rigidity, postural instability, bradykinesia, and resting tremor. These motor symptoms might cause gait dysfunction. Gait dysfunction represented a common sign of PD, including reduced gait velocity, reduced stride length, reduced arm swing, and increased gait variability. Poor postural control in people with PD might result to increase gait variability and then increase fall risk. Previous studies reported that proprioceptive-vestibular multisensory training improved postural stability in people with PD. However, no literature investigated the effects of proprioceptive-vestibular multisensory training on gait variability. Therefore, the purpose of this study is to examine the effect of proprioceptive-vestibular multisensory training on gait variability in people with PD.

Conditions

Parkinson Disease

Keywords

Multisensory training; Gait variability

Outcome Measures

Primary Outcomes (1)

• Gait variability

  Using GAITRite system to measure coefficient of variation

  Change from baseline at 6 weeks

Secondary Outcomes (4)

• Gait performance

  Change from baseline at 6 weeks

• Sensory organization test

  Change from baseline at 6 weeks

• Timed up and go test

  Change from baseline at 6 weeks

• Dynamic Gait Index

  Change from baseline at 6 weeks

Study Arms (2)

Multisensory training group

EXPERIMENTAL

The intervention is a 50-minute session and 2-sessions/week, totaling 6 weeks

Other: Multisensory training

Conventional training group.

ACTIVE COMPARATOR

The intervention is a 50-minute session and 2-sessions/week, totaling 6 weeks

Other: Conventional training

Interventions

Multisensory training OTHER

Multisensory training included marching on the foam with visual deprivation and treadmill training with visual deprivation

Multisensory training group

Conventional training OTHER

Conventional training included strengthening, balance training and gait training

Conventional training group.

Eligibility Criteria

• Age: 50 Years - 80 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• Idiopathic PD
• Hoehn and Yahr stage I to III
• Age 60\~80 y/o
• Mini-Mental State Examination (MMSE) ≥24
• Ability to ambulate independently (with or without walking aid)

You may not qualify if:

• Affecting the peripheral vestibular system
• Medical condition that substantially influenced their gait and balance performance
• People had joined any rehabilitation past 1 month

Sponsors & Collaborators

• National Yang Ming Chiao Tung University: lead

MeSH Terms

Conditions

Parkinson Disease

Condition Hierarchy (Ancestors)

Parkinsonian Disorders; Basal Ganglia Diseases; Brain Diseases; Central Nervous System Diseases; Nervous System Diseases; Movement Disorders; Synucleinopathies; Neurodegenerative Diseases

Central Study Contacts

Yang Yea-Ru, PhD

CONTACT

+886228267279; yryang@nycu.edu.tw

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: SINGLE
• Who Masked: OUTCOMES ASSESSOR
• Purpose: TREATMENT
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Professor

Study Record Dates

• First Submitted: August 21, 2021
• First Posted: August 30, 2021
• Study Start: September 1, 2021
• Primary Completion: December 31, 2022
• Study Completion: December 31, 2022
• Last Updated: August 30, 2021

Record last verified: 2021-08