NCT04062500

Brief Summary

The purpose of this registry is to compile a large clinical database on the medical management of patients hospitalized with acute heart failure, using information collected from hospitals across China.

Trial Health

77
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
10,500

participants targeted

Target at P75+ for all trials

Timeline
20mo left

Started Jan 2018

Longer than P75 for all trials

Geographic Reach
1 country

1 active site

Status
recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Progress84%
Jan 2018Dec 2027

Study Start

First participant enrolled

January 1, 2018

Completed
1.6 years until next milestone

First Submitted

Initial submission to the registry

August 9, 2019

Completed
11 days until next milestone

First Posted

Study publicly available on registry

August 20, 2019

Completed
1.4 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

December 31, 2020

Completed
7 years until next milestone

Study Completion

Last participant's last visit for all outcomes

December 31, 2027

Expected
Last Updated

August 17, 2020

Status Verified

August 1, 2020

Enrollment Period

3 years

First QC Date

August 9, 2019

Last Update Submit

August 14, 2020

Conditions

Keywords

Heart Failure,prognostic, registry

Outcome Measures

Primary Outcomes (2)

  • Mortality of acute decompensated heart failure

    In-hospital and Annual mortality

    10 years

  • Re-hospitalization rate

    Re-hospitalization of acute decompensated heart failure

    10 years

Study Arms (1)

Patients with heart failure

patients treated in the hospital for acute heart failure in China

Other: Mortality and Rehospitalization rate

Interventions

Mortality and Re-hospitalization of acute decompensated heart failure

Patients with heart failure

Eligibility Criteria

Age18 Years - 90 Years
Sexall
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodProbability Sample
Study Population

Patients with heart failure

You may qualify if:

  • \- 1. 18 years and older. 2. Meet the diagnostic criteria of China 2018 or JACC/AHA 2017 or ESC 2016 heart failure guidelines.
  • \. Agree to be tested and sign an informed consent certificate.

You may not qualify if:

  • \. Age\<18 years old. 2. Patients who refused to participate. 3. Patients may have a life expectancy of less than 1 years due to non- heart failure clinical conditions.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Shanghai Tenth People's Hospital, Tongji University

Shanghai, Shanghai Municipality, 200072, China

RECRUITING

Related Publications (1)

  • Su Y, Ma M, Zhang H, Pan X, Zhang X, Zhang F, Lv Y, Yan C. Prognostic value of serum hyponatremia for outcomes in patients with heart failure with preserved ejection fraction: An observational cohort study. Exp Ther Med. 2020 Nov;20(5):101. doi: 10.3892/etm.2020.9231. Epub 2020 Sep 17.

Biospecimen

Retention: SAMPLES WITHOUT DNA

Human serum from enrolled patients

MeSH Terms

Conditions

Heart Failure

Interventions

Mortality

Condition Hierarchy (Ancestors)

Heart DiseasesCardiovascular Diseases

Intervention Hierarchy (Ancestors)

Vital StatisticsData CollectionEpidemiologic MethodsInvestigative TechniquesDemographyPopulation CharacteristicsEpidemiologic MeasurementsPublic HealthEnvironment and Public Health

Study Officials

  • Dachun Xu, PhD

    Shanghai Tenthth People's Hospital

    PRINCIPAL INVESTIGATOR

Central Study Contacts

Dachun Xu, PhD

CONTACT

Study Design

Study Type
observational
Observational Model
COHORT
Time Perspective
PROSPECTIVE
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
MD, pHD, Director of Cardiovascular Department

Study Record Dates

First Submitted

August 9, 2019

First Posted

August 20, 2019

Study Start

January 1, 2018

Primary Completion

December 31, 2020

Study Completion (Estimated)

December 31, 2027

Last Updated

August 17, 2020

Record last verified: 2020-08

Locations