Seizures in Infants Hospitalized in Pediatric Intensive Care Unit for Bronchiolitis

NCT04022486 | Completed

• 1 other identifier: Bronchiolitis
• Study Type: observational
• Target: 805
• Locations: 1 country
• Sites: 1

Brief Summary

Bronchiolitis is the leading cause of pediatric intensive care unit admission in infants. Seizures during bronchiolitis may be a neurological complication of respiratory viruses but also of the treatments. The investigating team's hypothesis is that the incidence of seizures is not so so uncommon in infants hospitalized in the pediatric intensive care unit for severe bronchiolitis.

Conditions

Bronchiolitis; Seizures; Hyponatremia

Keywords

Infant

Outcome Measures

Primary Outcomes (1)

• : Incidence of seizure during bronchiolitis (before or during hospitalization in the pediatric intensive care unit)

  Clinical or infra-clinical (diagnosed on Electroencephalography, EEG) seizure, simple or status epilepticus

  Day 1

Study Arms (1)

Children admitted in the PICU for severe bronchiolitis

Children admitted in the Pediatric Intensive Care Unit (PICU) for severe bronchiolitis between January 1st, 2010 and April 30th, 2018

Other: Incidence, management and risk factors of seizure

Interventions

Incidence, management and risk factors of seizure OTHER

Incidence of seizure, management (treatment, paraclinical examinations) and risk factors of seizure in children admitted for severe bronchiolitis

Children admitted in the PICU for severe bronchiolitis

Eligibility Criteria

• Age: Up to 90 Days
• Sex: all
• Healthy Volunteers: No
• Age Groups: Child (0-17)
• Sampling Method: Non-Probability Sample

Study Population

All children hospitalized in the pediatric intensive care unit

You may qualify if:

• age \< 90 days
• hospitalization from January 1st, 2010 to April 30th, 2018 in the Pediatric Intensive Care Unit (PICU) of pediatric hospital in Lyon
• with bronchiolitis (clinical diagnosis according to American Academy of Pediatrics)

You may not qualify if:

• neurological history that may explain the occurrence of seizures
• significant congenital heart disease

Sponsors & Collaborators

• Hospices Civils de Lyon: lead

Study Sites (1)

Hôpital Femme Mère Enfant

Bron, 69677, France

Location

MeSH Terms

Conditions

Bronchiolitis; Seizures; Hyponatremia

Interventions

Incidence; Therapeutics

Condition Hierarchy (Ancestors)

Bronchitis; Respiratory Tract Infections; Infections; Bronchial Diseases; Respiratory Tract Diseases; Lung Diseases, Obstructive; Lung Diseases; Neurologic Manifestations; Nervous System Diseases; Signs and Symptoms; Pathological Conditions, Signs and Symptoms; Water-Electrolyte Imbalance; Metabolic Diseases; Nutritional and Metabolic Diseases

Intervention Hierarchy (Ancestors)

Morbidity; Vital Statistics; Data Collection; Epidemiologic Methods; Investigative Techniques; Demography; Population Characteristics; Epidemiologic Measurements; Public Health; Environment and Public Health

Study Officials

• Florent BAUDIN, MD

  Hospices Civils de Lyon

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: RETROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: July 15, 2019
• First Posted: July 17, 2019
• Study Start: April 1, 2018
• Primary Completion: August 1, 2018
• Study Completion: May 1, 2019
• Last Updated: July 17, 2019

Record last verified: 2019-07

Locations

FR (1)