NCT04135430

Brief Summary

Infant bronchiolitis is a frequent pathology that is the cause of a very large number of medical outpatient and physiotherapy treatments in France. Many international studies and recommendations have invalidated any drug treatment during its management during the first episode. In France, the consensus conference promoted by the National Agency for Accreditation and Health Evaluation (ANAES) in September 2000 was in the same vein. Regarding the respiratory physiotherapy component, posture drainage, vibration and percussion are not considered effective. ANAES recommended the use of respiratory physiotherapy with passive exhalation techniques. This is a method of care that has developed mainly in French-speaking countries, making it difficult to compare with the habits of Anglo-Saxon countries, which, more generally, do not prescribe it. In France, the level of evidence of its effectiveness is considered low (grade C). To date, the vast majority of studies have focused exclusively on a population of infants hospitalized for severe bronchiolitis. For this type of population, the value of such treatment to shorten the healing time has not been demonstrated. So much so that the ANAES, in its time, recommended that studies be carried out "on an outpatient basis" to assess their degree. In this respect, several recent studies have provided new data. Despite the reservations inherent in their methodologies and/or staff, they raise the question of the interest of the respiratory physiotherapy on an outpatient basis. In terms of professional practice, the American recommendations state that clinicians should educate family members about evidence-based diagnosis, treatment and prevention in bronchiolitis. Finally, an opinion survey concludes that holders of parental authority are seeking information on bronchiolitis and that approximately 90% have read the brochure given out of the maternity ward explaining the modes of transmission, manifestations, care and hygiene measures in the event of bronchiolitis. Pending new French recommendations, it seems legitimate to evaluate the level of perception of the effect of pediatric respiratory physiotherapy with increase in expiratory flow (IEF) in urban practice on the respiratory comfort of infants directly with families confronted with this pathology.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
192

participants targeted

Target at P50-P75 for all trials

Timeline
Completed

Started Oct 2019

Geographic Reach
1 country

11 active sites

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

September 30, 2019

Completed
14 days until next milestone

Study Start

First participant enrolled

October 14, 2019

Completed
8 days until next milestone

First Posted

Study publicly available on registry

October 22, 2019

Completed
1.4 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

March 27, 2021

Completed
8 days until next milestone

Study Completion

Last participant's last visit for all outcomes

April 4, 2021

Completed
Last Updated

June 8, 2021

Status Verified

June 1, 2021

Enrollment Period

1.5 years

First QC Date

September 30, 2019

Last Update Submit

June 7, 2021

Conditions

Keywords

BronchiolitisInfantsChest physiotherapy

Outcome Measures

Primary Outcomes (1)

  • QUALIN score

    Evolution of the Quality of life of infants and young children (QUALIN) score between before the session and 12 to 24 hours after the session.

    24 hours

Secondary Outcomes (5)

  • Questionnaire about accessibility of the care chain

    8 days

  • Questionnaire about understanding of the information

    8 days

  • Questionnaire about perceived professional competence.

    8 days

  • Questionnaire about security of care

    8 days

  • Questionnaire about child's respiratory comfort

    8 days

Study Arms (1)

Survey

Practice of an updated questionnaire at D0, D2 and D7

Other: Survey

Interventions

SurveyOTHER

practice of an updated questionnaire at D0, D2 and D7

Survey

Eligibility Criteria

AgeUp to 1 Year
Sexall
Healthy VolunteersNo
Age GroupsChild (0-17)
Sampling MethodNon-Probability Sample
Study Population

Infants up to 12 months of age with first or second episode bronchiolitis

You may qualify if:

  • Infant up to 12 months of age
  • Wang's score ≥ at 4 and \< 9
  • With first or second episode of bronchiolitis with a medical prescription for respiratory physiotherapy in the city.
  • Consultation for a first session, or second session of respiratory physiotherapy

You may not qualify if:

  • History or atopic predisposition
  • History(s) of prematurity (34 weeks of amenorrhea or less)
  • History of bronchopulmonary dysplasia
  • Underlying heart disease, severe chronic lung disease
  • Contraindication to the use of Kinesitherapy: prolonged corticosteroid therapy (more than one month), rickets, osteogenesis imperfecta, thrombocytopenia, rib fracture
  • Opposition of holders of parental authority

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (11)

Rb Picard

Amiens, France

Location

RB 74

Annecy-le-Vieux, France

Location

GAB

Arpajon, France

Location

Aquirespi

Bordeaux, France

Location

Rb Loiret

Fleury-les-Aubrais, France

Location

La Rochelle

La Rochelle, France

Location

Occirespi

Léguevin, France

Location

Rb Grand Est

Malzéville, France

Location

ARBAM

Marseille, France

Location

CHU Robert-Debré

Paris, France

Location

RB 59 62

Seclin, France

Location

MeSH Terms

Conditions

Bronchiolitis

Interventions

Surveys and Questionnaires

Condition Hierarchy (Ancestors)

BronchitisRespiratory Tract InfectionsInfectionsBronchial DiseasesRespiratory Tract DiseasesLung Diseases, ObstructiveLung Diseases

Intervention Hierarchy (Ancestors)

Data CollectionEpidemiologic MethodsInvestigative TechniquesHealth Care Evaluation MechanismsQuality of Health CareHealth Care Quality, Access, and EvaluationPublic HealthEnvironment and Public Health

Study Design

Study Type
observational
Observational Model
COHORT
Time Perspective
PROSPECTIVE
Sponsor Type
UNKNOWN
Responsible Party
SPONSOR

Study Record Dates

First Submitted

September 30, 2019

First Posted

October 22, 2019

Study Start

October 14, 2019

Primary Completion

March 27, 2021

Study Completion

April 4, 2021

Last Updated

June 8, 2021

Record last verified: 2021-06

Data Sharing

IPD Sharing
Will not share

Locations