Hypophosphatemia and Bronchiolitis
Hypophosphatemia In Infants With Severe Bronchiolitis: Prevalence And Risk Factors
1 other identifier
observational
400
1 country
1
Brief Summary
Bronchiolitis is a major public health problem and the leading cause of paediatric intensive care unit admission in infants. Hypophosphatemia is common in adult intensive care units and was associated with an increase of the duration of mechanical ventilation and the length of stay. Our hypothesis is that hypophosphatemia is common in bronchiolitis and could be a marker of severity.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P75+ for all trials
Started Mar 2021
Shorter than P25 for all trials
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
Study Start
First participant enrolled
March 21, 2021
CompletedFirst Submitted
Initial submission to the registry
March 22, 2021
CompletedFirst Posted
Study publicly available on registry
March 24, 2021
CompletedPrimary Completion
Last participant's last visit for primary outcome
May 1, 2021
CompletedStudy Completion
Last participant's last visit for all outcomes
June 1, 2021
CompletedMarch 24, 2021
March 1, 2021
1 month
March 22, 2021
March 22, 2021
Conditions
Keywords
Outcome Measures
Primary Outcomes (1)
hypophosphatemia occurrence in severe bronchiolitis in infants admitted in a pediatric intensive care unit
A serum phosphorus level\< 1.55mmol/L defines the hypophosphatemia.
At any time in the first 5th days after Pediatric intensive care admission
Study Arms (2)
Infants with hypophosphatemia
Infant less than 3 months with severe bronchiolitis admitted in a pediatric intensive care unit, with hypophosphatemia in the first 5th days
Infants without hypophosphatemia
Infant less than 3 months with severe bronchiolitis admitted in a pediatric intensive care unit, without hypophosphatemia
Interventions
Serum phosphorus level \< 1.55 mmol/L at any time between admission and the 5th day.
Eligibility Criteria
Infant less than 3 months with severe bronchiolitis admitted in a pediatric intensive care unit
You may qualify if:
- Age \> 7 days and \< 3 months of life
- Admission to the pediatric intensive care unit from 01/11/2016 to 31/03/2020
- With a diagnosis of moderate to severe bronchiolitis according to HAS 2019 criteria
You may not qualify if:
- Renal Failure and tubulopathy
- Previous disorder of phospho-calcium balance
- Malignant pathology
- Lenght of stay less than 24 hours
- History of cardiac, aortic or hepatic surgery
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Study Sites (1)
Hopital Femme Mere Enfant - Groupement Hospitalier Est
Bron, 69677, France
MeSH Terms
Conditions
Condition Hierarchy (Ancestors)
Central Study Contacts
Study Design
- Study Type
- observational
- Observational Model
- CASE CONTROL
- Time Perspective
- RETROSPECTIVE
- Sponsor Type
- OTHER
- Responsible Party
- SPONSOR
Study Record Dates
First Submitted
March 22, 2021
First Posted
March 24, 2021
Study Start
March 21, 2021
Primary Completion
May 1, 2021
Study Completion
June 1, 2021
Last Updated
March 24, 2021
Record last verified: 2021-03