Hyponatremia
112
6
9
68
Key Insights
Highlights
Success Rate
81% trial completion
Published Results
21 trials with published results (19%)
Research Maturity
68 completed trials (61% of total)
Clinical Risk Assessment
Based on trial outcomes
Moderate Risk
Score: 52/100
14.3%
16 terminated out of 112 trials
81.0%
-5.6% vs benchmark
32%
36 trials in Phase 3/4
31%
21 of 68 completed with results
Key Signals
Data Visualizations
Phase Distribution
Trial Status
Trial Success Rate
Benchmark: 86.5%
Based on 68 completed trials
Clinical Trials (112)
Study of Ascending Levels of Tolvaptan in Hyponatremia
Analysis of the Epidemiology, Clinical Presentation and Therapy as Well as Therapy-associated Risk of Demyelination Syndrome in Patients With Profound Hyponatremia in the Emergency Department
Hyponatremia in the Elderly: Benefit From a Change in Drug Therapy?
Hyponatremia - Complications, Prognosis, Epidemiology in Finnish Tertiary Care
Effect of Protein Supplementation and Fluid Restriction on Plasma Sodium Levels in Patients Undergoing Pituitary Surgery
Retrospective Analysis of ECG Changes and Arrhythmias in Patients With Profound Hyponatremia
Effects of the SGLT2 Inhibitor Empagliflozin in Patients With Euvolemic and Hypervolemic Hyponatremia
Regulation of Extracellular Sodium in End Stage Renal Disease Upon Volume and Electrolyte Challenges
Targeted Correction of Plasma Sodium Levels in Hospitalized Patients With Hyponatremia
Protein Supplementation in Hyponatremia Due to the Syndrome of Inappropriate Antidiuresis
Influence of Serum Sodium Levels on Bone Metabolism and Turnover in Hospitalized Patients
Systematic Use of DDAVP to Prevent Serum Sodium Overcorrection in Severe Hyponatremia
Urea Therapy for Hyponatremia in Subarachnoid Hemorrhage
Effects of Intravenous [Pyr1]Apelin-13 on Healthy Volunteers With Artificially Induced SIAD
Delirium Related to Proton Pump Inhibitors Use
Hyponatremia Volume Status Analysis by Point-of-care Ultrasound
Mortality and Neurologic Outcomes in Rapid vs. Slow Hyponatremia Correction
Hyponatremia Study (Delayed Hyponatremia After Pituitary Surgery)
Saline Infusion Test in Hyponatremia
Comparison of Isotonic Versus Hypotonic Fluids in Neonates for Maintenance Fluid Therapy After Surgery