Key Insights

Highlights

Success Rate

81% trial completion

Published Results

21 trials with published results (19%)

Research Maturity

68 completed trials (61% of total)

Clinical Risk Assessment

Based on trial outcomes

Moderate Risk

Score: 52/100

Termination Rate

14.3%

16 terminated out of 112 trials

Success Rate

81.0%

-5.6% vs benchmark

Late-Stage Pipeline

32%

36 trials in Phase 3/4

Results Transparency

31%

21 of 68 completed with results

Key Signals

21 with results81% success16 terminated

Data Visualizations

Phase Distribution

70Total
Not Applicable (25)
P 1 (4)
P 2 (5)
P 3 (25)
P 4 (11)

Trial Status

Completed68
Terminated16
Unknown13
Recruiting6
Withdrawn5
Active Not Recruiting3

Trial Success Rate

81.0%

Benchmark: 86.5%

Based on 68 completed trials

Clinical Trials (112)

Showing 20 of 20 trials
NCT00201994Phase 3CompletedPrimary

Study of Ascending Levels of Tolvaptan in Hyponatremia

NCT06781710CompletedPrimary

Analysis of the Epidemiology, Clinical Presentation and Therapy as Well as Therapy-associated Risk of Demyelination Syndrome in Patients With Profound Hyponatremia in the Emergency Department

NCT01212211Not ApplicableCompletedPrimary

Hyponatremia in the Elderly: Benefit From a Change in Drug Therapy?

NCT07430787Active Not RecruitingPrimary

Hyponatremia - Complications, Prognosis, Epidemiology in Finnish Tertiary Care

NCT07273630Not ApplicableRecruitingPrimary

Effect of Protein Supplementation and Fluid Restriction on Plasma Sodium Levels in Patients Undergoing Pituitary Surgery

NCT07255833CompletedPrimary

Retrospective Analysis of ECG Changes and Arrhythmias in Patients With Profound Hyponatremia

NCT04447911Phase 4RecruitingPrimary

Effects of the SGLT2 Inhibitor Empagliflozin in Patients With Euvolemic and Hypervolemic Hyponatremia

NCT06408077Not ApplicableRecruitingPrimary

Regulation of Extracellular Sodium in End Stage Renal Disease Upon Volume and Electrolyte Challenges

NCT03557957Not ApplicableCompletedPrimary

Targeted Correction of Plasma Sodium Levels in Hospitalized Patients With Hyponatremia

NCT06821802Not ApplicableRecruitingPrimary

Protein Supplementation in Hyponatremia Due to the Syndrome of Inappropriate Antidiuresis

NCT04227301CompletedPrimary

Influence of Serum Sodium Levels on Bone Metabolism and Turnover in Hospitalized Patients

NCT06020495Phase 3RecruitingPrimary

Systematic Use of DDAVP to Prevent Serum Sodium Overcorrection in Severe Hyponatremia

NCT04552873Not ApplicableActive Not RecruitingPrimary

Urea Therapy for Hyponatremia in Subarachnoid Hemorrhage

NCT06277336Not ApplicableCompleted

Effects of Intravenous [Pyr1]Apelin-13 on Healthy Volunteers With Artificially Induced SIAD

NCT05815550Completed

Delirium Related to Proton Pump Inhibitors Use

NCT06013800Active Not RecruitingPrimary

Hyponatremia Volume Status Analysis by Point-of-care Ultrasound

NCT06675591CompletedPrimary

Mortality and Neurologic Outcomes in Rapid vs. Slow Hyponatremia Correction

NCT03636568Not ApplicableCompletedPrimary

Hyponatremia Study (Delayed Hyponatremia After Pituitary Surgery)

NCT06498856Not Yet RecruitingPrimary

Saline Infusion Test in Hyponatremia

NCT06484608Not ApplicableCompletedPrimary

Comparison of Isotonic Versus Hypotonic Fluids in Neonates for Maintenance Fluid Therapy After Surgery

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