NCT04021147

Brief Summary

The main objective of the present study was to evaluate the effects of action observation (AO), visual mirror feedback (VMF), motor imagery (MI) combined with an orofacial exercise program in asymptomatic subjects.

Trial Health

43
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
55

participants targeted

Target at P25-P50 for not_applicable

Timeline
Completed

Started Jul 2019

Shorter than P25 for not_applicable

Geographic Reach
1 country

1 active site

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

July 8, 2019

Completed
7 days until next milestone

Study Start

First participant enrolled

July 15, 2019

Completed
1 day until next milestone

First Posted

Study publicly available on registry

July 16, 2019

Completed
25 days until next milestone

Primary Completion

Last participant's last visit for primary outcome

August 10, 2019

Completed
5 days until next milestone

Study Completion

Last participant's last visit for all outcomes

August 15, 2019

Completed
Last Updated

July 22, 2019

Status Verified

July 1, 2019

Enrollment Period

26 days

First QC Date

July 8, 2019

Last Update Submit

July 19, 2019

Conditions

Keywords

Motor ImageryAction observationVisual mirror feedbackPain pressure thresholds

Outcome Measures

Primary Outcomes (2)

  • Pain pressure thresholds (PPTs)

    PPT is defined as the minimal amount of pressure where a sense of pressure first changes to pain. The mechanical pressure algometer (Force Ten TM FDX Digital Force Gage) used in this study consisted of a round rubber disk (area, 1 cm2) attached to a pressure (force) gauge. The gauge displays values in kilograms but, because the surface of the rubber tip is 1 cm2, the readings are expressed in kg/cm2. The range of values of the pressure algometer is 0 to 10 kg, with 0.1-kg divisions. The pressure was applied at a rate of 0.31 kg/second (Chesterton et al. 2007). Chesterton et al. (2007) have shown that the reliability of pressure algometry is as high as \[ICC=0.91 (95% confidence interval, CI 0.82-0.97)\].

    Change from baseline and immediately post-intervention

  • Lingual muscle endurance

    Lingual muscle endurance was assessed using the Iowa Oral Performance Instrument (IOPI) (Adams et al. 2015). The measurement of muscular endurance was carried out by placing a plastic bulb with oblong air content on the hard palate, posterior to the central incisor teeth. The participants were asked to elevate the lingual (through anterior and posterior lingual region) to press the instrument with the maximum possible force for 3 seconds, while monitoring the force exerted, quantified in Newtons. Adams et al. (2015) found moderate to strong reliability for anterior (ICC: 0.58-0.77) and posterior (ICC 0.77-0.84) tongue strength.

    Change from baseline and immediately post-intervention

Secondary Outcomes (3)

  • Maximal mouth opening (MMO)

    Change from baseline and immediately post-intervention

  • Lingual extensibility

    Change from baseline and immediately post-intervention

  • Ability to generate mental motor images

    Change from baseline and immediately post-intervention

Study Arms (4)

Action Observation

EXPERIMENTAL
Behavioral: Exercise plus action observation

Motor Imagery

EXPERIMENTAL
Behavioral: Exercise plus motor imagery

Visual mirror feedback

EXPERIMENTAL
Behavioral: Exercise plus visual mirror feedback

Orofacial exercise

ACTIVE COMPARATOR
Behavioral: Exercise

Interventions

Orofacial exercise plus action observation (video) of the same exercise

Action Observation

Orofacial exercise plus motor imagery of the same exercise

Motor Imagery

Exercise plus visual mirror feedback

Visual mirror feedback
ExerciseBEHAVIORAL

Orofacial exercises

Orofacial exercise

Eligibility Criteria

Age18 Years - 65 Years
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • healthy individuals with no pain
  • aged between 18 and 65 years
  • subjects with correct masticatory function and labial and lingual mobility

You may not qualify if:

  • individuals who presented systemic, cardiorespiratory, central nervous system or rheumatic diseases, or those who presented any musculoskeletal or craniocervical pathology
  • underage individuals
  • individuals with orofacial pain or temporomandibular disorders at the time of the study; (d) subjects' complaint of toothache or tenderness to percussion.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

CSEU La Salle

Madrid, 28023, Spain

Location

MeSH Terms

Conditions

Motor ActivityPain

Interventions

Exercise

Condition Hierarchy (Ancestors)

BehaviorNeurologic ManifestationsSigns and SymptomsPathological Conditions, Signs and Symptoms

Intervention Hierarchy (Ancestors)

Motor ActivityMovementMusculoskeletal Physiological PhenomenaMusculoskeletal and Neural Physiological Phenomena

Central Study Contacts

Luis Suso Martí

CONTACT

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
QUADRUPLE
Who Masked
PARTICIPANT, CARE PROVIDER, INVESTIGATOR, OUTCOMES ASSESSOR
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Principal Investigator

Study Record Dates

First Submitted

July 8, 2019

First Posted

July 16, 2019

Study Start

July 15, 2019

Primary Completion

August 10, 2019

Study Completion

August 15, 2019

Last Updated

July 22, 2019

Record last verified: 2019-07

Locations